| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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71 genes differentially expressed following the CRCGN008_HEPG2_24H:B04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYCS | cytochrome c, somatic | 6.1297 |
| E2F2 | E2F transcription factor 2 | 5.7229 |
| STIMATE | STIM activating enhancer | 5.18245 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.895 |
| CBR3 | carbonyl reductase 3 | 4.7429 |
| ARL4C | ADP-ribosylation factor-like 4C | 4.41262 |
| LOC122526780 | uncharacterized LOC122526780 | 4.29165 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.81155 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 3.69391 |
| EGF | epidermal growth factor | 3.5776 |
| PNRC2 | proline-rich nuclear receptor coactivator 2 | 3.07325 |
| TBXA2R | thromboxane A2 receptor | 2.83021 |
| GPC1 | glypican 1 | 2.5038 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 2.4826 |
| GRB10 | growth factor receptor-bound protein 10 | 2.42445 |
| PRDX4 | peroxiredoxin 4 | 2.3739 |
| CLTC | clathrin, heavy chain (Hc) | 2.3566 |
| COX6C | cytochrome c oxidase subunit VIc | 2.30875 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.30373 |
| NEK4 | NIMA-related kinase 4 | 2.28615 |
| ZNF589 | zinc finger protein 589 | 2.26942 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 2.2537 |
| CDCA4 | cell division cycle associated 4 | 2.24375 |
| TPST2 | tyrosylprotein sulfotransferase 2 | 2.2383 |
| TENM4 | teneurin transmembrane protein 4 | 2.2117 |
| TMEM33 | transmembrane protein 33 | 2.20235 |
| NLGN4X | neuroligin 4, X-linked | 2.2018 |
| LCN2 | lipocalin 2 | 2.1921 |
| GLDC | glycine dehydrogenase (decarboxylating) | 2.1737 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase | 2.1431 |
| PTBP1 | polypyrimidine tract binding protein 1 | 2.14234 |
| SLC52A2 | solute carrier family 52 (riboflavin transporter), member 2 | 2.13882 |
| GCDH | glutaryl-CoA dehydrogenase | 2.0425 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | 2.03347 |
| EVL | Enah/Vasp-like | 2.03045 |
| CRYBB1 | crystallin, beta B1 | 2.0159 |
| TUBB2B | tubulin, beta 2B class IIb | 2.01575 |
| CDC34 | cell division cycle 34 | 2.013 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.0058 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -8.70725 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -6.48565 |
| UGDH | UDP-glucose 6-dehydrogenase | -5.5844 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -5.29865 |
| ADI1 | acireductone dioxygenase 1 | -5.0303 |
| PCNA | proliferating cell nuclear antigen | -5.0 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -4.85895 |
| LDHD | lactate dehydrogenase D | -4.765 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.62445 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -4.5203 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -3.98795 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | -3.64415 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -3.18055 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.13098 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.686 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -2.63605 |
| RBM34 | RNA binding motif protein 34 | -2.5474 |
| SNX11 | sorting nexin 11 | -2.52105 |
| NGRN | neugrin, neurite outgrowth associated | -2.50395 |
| SESN1 | sestrin 1 | -2.4446 |
| CDC25B | cell division cycle 25B | -2.3758 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -2.36475 |
| ARMH3 | armadillo like helical domain containing 3 | -2.27012 |
| ADH7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | -2.2367 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -2.22685 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.20785 |
| AREL1 | apoptosis resistant E3 ubiquitin protein ligase 1 | -2.1027 |
| INTS14 | integrator complex subunit 14 | -2.09975 |
| GINS3 | GINS complex subunit 3 (Psf3 homolog) | -2.08087 |
| RGS2 | regulator of G-protein signaling 2 | -2.07015 |
| CALML4 | calmodulin-like 4 | -2.04467 |
| ARL2 | ADP-ribosylation factor-like 2 | -2.0109 |
