CRCGN008_HEPG2_24H:B09 Gene Set
Genes
40 genes differentially expressed following the CRCGN008_HEPG2_24H:B09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOTCH1
|
notch 1
|
5.4495
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
5.02205
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.00455
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
4.882
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.79255
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.57295
|
|
STIMATE
|
STIM activating enhancer
|
3.86665
|
|
TBPL1
|
TBP-like 1
|
3.7636
|
|
ADO
|
2-aminoethanethiol (cysteamine) dioxygenase
|
3.58493
|
|
MAP7
|
microtubule-associated protein 7
|
3.28868
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.25205
|
|
CDCA4
|
cell division cycle associated 4
|
3.23445
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.23303
|
|
TBP
|
TATA box binding protein
|
3.1929
|
|
JADE2
|
jade family PHD finger 2
|
3.17193
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.9744
|
|
MAST2
|
microtubule associated serine/threonine kinase 2
|
2.60798
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.5668
|
|
FPGS
|
folylpolyglutamate synthase
|
2.48025
|
|
SKIC8
|
SKI8 subunit of superkiller complex
|
2.273
|
|
RSAD2
|
radical S-adenosyl methionine domain containing 2
|
2.16675
|
|
IFIT1
|
interferon-induced protein with tetratricopeptide repeats 1
|
2.1663
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-5.27735
|
|
HSPB1
|
heat shock 27kDa protein 1
|
-4.98635
|
|
LDHD
|
lactate dehydrogenase D
|
-4.93295
|
|
CCNB2
|
cyclin B2
|
-4.89435
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-4.86215
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-4.26805
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.82405
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.7671
|
|
SCAND1
|
SCAN domain containing 1
|
-3.69285
|
|
RNF167
|
ring finger protein 167
|
-3.53005
|
|
CCNB1
|
cyclin B1
|
-2.54855
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
-2.48215
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-2.19607
|
|
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1
|
-2.11545
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.08515
|
|
NDC80
|
NDC80 kinetochore complex component
|
-2.06385
|
|
SDF2
|
stromal cell-derived factor 2
|
-2.01295
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
-2.0096
|
