CRCGN008_HEPG2_24H:B10 Gene Set
Genes
43 genes differentially expressed following the CRCGN008_HEPG2_24H:B10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CCDC92
|
coiled-coil domain containing 92
|
5.39155
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.98395
|
|
CBR3
|
carbonyl reductase 3
|
4.9784
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
4.8357
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
4.3545
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.9052
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.85862
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.75135
|
|
CYCS
|
cytochrome c, somatic
|
3.4168
|
|
CHN1
|
chimerin 1
|
2.89315
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.79445
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.7257
|
|
SATB1
|
SATB homeobox 1
|
2.6156
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.49605
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.49528
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.4205
|
|
SPG21
|
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
|
2.29255
|
|
TRAPPC12
|
trafficking protein particle complex 12
|
2.28855
|
|
GPATCH8
|
G patch domain containing 8
|
2.26743
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.2195
|
|
USP6NL
|
USP6 N-terminal like
|
2.187
|
|
MTX2
|
metaxin 2
|
2.15965
|
|
HGS
|
hepatocyte growth factor-regulated tyrosine kinase substrate
|
2.098
|
|
VPS54
|
vacuolar protein sorting 54 homolog (S. cerevisiae)
|
2.01365
|
|
PFDN2
|
prefoldin subunit 2
|
2.004
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-5.1905
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.70845
|
|
CTSD
|
cathepsin D
|
-4.5615
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-3.8717
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.75303
|
|
RNF167
|
ring finger protein 167
|
-2.7455
|
|
ZNF586
|
zinc finger protein 586
|
-2.5277
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.51347
|
|
PSMD2
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
|
-2.5111
|
|
ATF5
|
activating transcription factor 5
|
-2.46143
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
-2.46065
|
|
SEC22A
|
SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
|
-2.31675
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.30635
|
|
ELF3
|
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
|
-2.17545
|
|
LRPAP1
|
low density lipoprotein receptor-related protein associated protein 1
|
-2.1453
|
|
ETFDH
|
electron-transferring-flavoprotein dehydrogenase
|
-2.05377
|
|
TGFBR3
|
transforming growth factor, beta receptor III
|
-2.03835
|
