| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2,4,5-trichlorophenoxyacetic acid 1.25 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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59 genes differentially expressed following the CRCGN008_HEPG2_24H:B12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHMP6 | charged multivesicular body protein 6 | 10.0 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 7.3441 |
| GPER1 | G protein-coupled estrogen receptor 1 | 7.0179 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.76755 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.643 |
| NOTCH1 | notch 1 | 5.1231 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.52735 |
| SFTPB | surfactant protein B | 4.23163 |
| ABHD6 | abhydrolase domain containing 6 | 4.15058 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.87612 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.7389 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 3.3568 |
| CDCA4 | cell division cycle associated 4 | 3.2872 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.1407 |
| CYBC1 | cytochrome b-245 chaperone 1 | 3.0665 |
| NMU | neuromedin U | 3.0237 |
| CHN1 | chimerin 1 | 2.7592 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 2.5446 |
| PMVK | phosphomevalonate kinase | 2.49955 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 2.40875 |
| IL33 | interleukin 33 | 2.40775 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 2.30182 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 2.274 |
| ZNF589 | zinc finger protein 589 | 2.24178 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 2.23245 |
| AHNAK2 | AHNAK nucleoprotein 2 | 2.20745 |
| HAMP | hepcidin antimicrobial peptide | 2.1268 |
| GPX3 | glutathione peroxidase 3 | 2.09285 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 2.084 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine | 2.07645 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -6.0686 |
| DSG2 | desmoglein 2 | -5.513 |
| CCNB1 | cyclin B1 | -5.18755 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.06035 |
| TRIB3 | tribbles pseudokinase 3 | -4.8087 |
| PCNA | proliferating cell nuclear antigen | -4.77245 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.5989 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -4.44735 |
| ADI1 | acireductone dioxygenase 1 | -4.34285 |
| HMG20B | high mobility group 20B | -4.2505 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -4.06945 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -3.8317 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -3.77825 |
| RBM15B | RNA binding motif protein 15B | -3.4638 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.3939 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -3.10185 |
| WASHC4 | WASH complex subunit 4 | -2.76397 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -2.6742 |
| ABHD10 | abhydrolase domain containing 10 | -2.29085 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 | -2.28355 |
| ANKRD11 | ankyrin repeat domain 11 | -2.2822 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.11333 |
| GCSH | glycine cleavage system protein H (aminomethyl carrier) | -2.07288 |
| RIC3 | RIC3 acetylcholine receptor chaperone | -2.05395 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 | -2.049 |
| RSPH10B2 | radial spoke head 10 homolog B2 (Chlamydomonas) | -2.02465 |
| POLR2J3 | polymerase (RNA) II (DNA directed) polypeptide J3 | -2.01678 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.00845 |
