CRCGN008_HEPG2_24H:B13 Gene Set
Genes
46 genes differentially expressed following the CRCGN008_HEPG2_24H:B13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
5.59545
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
5.1693
|
|
E2F2
|
E2F transcription factor 2
|
5.1417
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.69995
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.48595
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
4.3622
|
|
NOTCH1
|
notch 1
|
4.24425
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
4.2011
|
|
FZD1
|
frizzled class receptor 1
|
3.60295
|
|
CHEK2
|
checkpoint kinase 2
|
3.2794
|
|
CEP57
|
centrosomal protein 57kDa
|
3.21674
|
|
MAP7
|
microtubule-associated protein 7
|
2.94088
|
|
SCRN1
|
secernin 1
|
2.9243
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
2.90365
|
|
DNAJB2
|
DnaJ (Hsp40) homolog, subfamily B, member 2
|
2.68385
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.35445
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.33755
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
2.28185
|
|
MBOAT7
|
membrane bound O-acyltransferase domain containing 7
|
2.25215
|
|
MLH1
|
mutL homolog 1
|
2.2226
|
|
VPS51
|
vacuolar protein sorting 51 homolog (S. cerevisiae)
|
2.1826
|
|
ESRP1
|
epithelial splicing regulatory protein 1
|
2.0882
|
|
OCLN
|
occludin
|
2.03265
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-10.0
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-5.19555
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-5.1773
|
|
LDHD
|
lactate dehydrogenase D
|
-5.0219
|
|
FASTKD5
|
FAST kinase domains 5
|
-5.00835
|
|
CCNB2
|
cyclin B2
|
-4.97585
|
|
CD320
|
CD320 molecule
|
-4.9286
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-4.02485
|
|
RHEB
|
Ras homolog enriched in brain
|
-3.63118
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.2518
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-2.9698
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.76045
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.55558
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.40815
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.3116
|
|
PDK4
|
pyruvate dehydrogenase kinase, isozyme 4
|
-2.30205
|
|
MAVS
|
mitochondrial antiviral signaling protein
|
-2.2068
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
-2.12745
|
|
LRPAP1
|
low density lipoprotein receptor-related protein associated protein 1
|
-2.0809
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
-2.05685
|
|
DDRGK1
|
DDRGK domain containing 1
|
-2.0557
|
|
CCL1
|
chemokine (C-C motif) ligand 1
|
-2.03925
|
|
SNRPB
|
small nuclear ribonucleoprotein polypeptides B and B1
|
-2.0108
|
