| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | metronidazole 5.13 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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70 genes differentially expressed following the CRCGN008_HEPG2_24H:B16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADRB2 | adrenoceptor beta 2, surface | 5.64695 |
| MAMLD1 | mastermind-like domain containing 1 | 5.43065 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.58555 |
| SATB1 | SATB homeobox 1 | 4.2868 |
| ABHD6 | abhydrolase domain containing 6 | 4.23978 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 4.15877 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.93435 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.89862 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.59907 |
| RXYLT1 | ribitol xylosyltransferase 1 | 3.46615 |
| PIH1D1 | PIH1 domain containing 1 | 3.4543 |
| EGF | epidermal growth factor | 3.4152 |
| PFKL | phosphofructokinase, liver | 3.39755 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 3.17397 |
| NOSIP | nitric oxide synthase interacting protein | 3.12905 |
| CCNF | cyclin F | 3.09318 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 3.03227 |
| KIF20A | kinesin family member 20A | 2.5927 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.52875 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.51395 |
| TBP | TATA box binding protein | 2.50725 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 2.4914 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 2.46775 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 | 2.46085 |
| CYCS | cytochrome c, somatic | 2.4322 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 2.3893 |
| SOD1 | superoxide dismutase 1, soluble | 2.38445 |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) | 2.30875 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 2.2894 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 2.2133 |
| FLNB | filamin B, beta | 2.20382 |
| RBM14-RBM4 | RBM14-RBM4 readthrough | 2.1691 |
| CORO1A | coronin, actin binding protein, 1A | 2.15415 |
| ZNF26 | zinc finger protein 26 | 2.1424 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 2.11963 |
| MARK1 | MAP/microtubule affinity-regulating kinase 1 | 2.0934 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 2.088 |
| EPHA3 | EPH receptor A3 | 2.0292 |
| Symbol | Name | Standardized Value |
|---|---|---|
| OXA1L | oxidase (cytochrome c) assembly 1-like | -6.3348 |
| CDC20 | cell division cycle 20 | -5.62735 |
| LDHD | lactate dehydrogenase D | -5.0219 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -4.99945 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.88805 |
| CCNB2 | cyclin B2 | -4.7794 |
| PCNA | proliferating cell nuclear antigen | -4.77245 |
| SLC35F2 | solute carrier family 35, member F2 | -4.6393 |
| GOLT1B | golgi transport 1B | -4.59145 |
| ENOPH1 | enolase-phosphatase 1 | -4.5818 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -4.35945 |
| CCNB1 | cyclin B1 | -4.03575 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.86468 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.19235 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.87235 |
| LGMN | legumain | -2.6218 |
| TWF2 | twinfilin actin binding protein 2 | -2.49015 |
| CAB39 | calcium binding protein 39 | -2.4775 |
| PCOLCE | procollagen C-endopeptidase enhancer | -2.41295 |
| TMEM265 | transmembrane protein 265 | -2.34255 |
| DNAJA2 | DnaJ (Hsp40) homolog, subfamily A, member 2 | -2.2979 |
| CLDN11 | claudin 11 | -2.23955 |
| PGM1 | phosphoglucomutase 1 | -2.2291 |
| THEMIS2 | thymocyte selection associated family member 2 | -2.2156 |
| RBM34 | RNA binding motif protein 34 | -2.21262 |
| CHRFAM7A | CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion | -2.1631 |
| IRF6 | interferon regulatory factor 6 | -2.1462 |
| FHL2 | four and a half LIM domains 2 | -2.10365 |
| HYI | hydroxypyruvate isomerase (putative) | -2.0807 |
| GALP | galanin-like peptide | -2.0258 |
| WARS2 | tryptophanyl tRNA synthetase 2, mitochondrial | -2.01605 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.0049 |
