CRCGN008_HEPG2_24H:B20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,4-dimethoxyaniline.hcl 20.2 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

65 genes differentially expressed following the CRCGN008_HEPG2_24H:B20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
WDR7 WD repeat domain 7 5.29225
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 5.22655
EPHB2 EPH receptor B2 5.15384
ALDOC aldolase C, fructose-bisphosphate 5.0124
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 4.7753
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 4.6654
PPARG peroxisome proliferator-activated receptor gamma 4.6533
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 4.43325
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 3.45566
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 3.31652
PMM2 phosphomannomutase 2 3.30715
HLA-DRA major histocompatibility complex, class II, DR alpha 3.21345
UBE2A ubiquitin-conjugating enzyme E2A 3.11678
CHN1 chimerin 1 3.0436
EPHA3 EPH receptor A3 2.9761
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.6973
NMU neuromedin U 2.65905
SSBP2 single-stranded DNA binding protein 2 2.64003
KIF20A kinesin family member 20A 2.53035
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 2.5285
TLR4 toll-like receptor 4 2.48585
TBP TATA box binding protein 2.48305
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.4637
IFNAR1 interferon (alpha, beta and omega) receptor 1 2.3798
CHEK2 checkpoint kinase 2 2.3667
RPGR retinitis pigmentosa GTPase regulator 2.34195
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 2.33035
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 2.29895
ADSL adenylosuccinate lyase 2.26645
PES1 pescadillo ribosomal biogenesis factor 1 2.1886
CIAO3 cytosolic iron-sulfur assembly component 3 2.17715
FAM204A family with sequence similarity 204, member A 2.11
NKRF NFKB repressing factor 2.0989
MYOZ3 myozenin 3 2.08105
WDTC1 WD and tetratricopeptide repeats 1 2.05543
TENT4A terminal nucleotidyltransferase 4A 2.04305
PRR14L proline rich 14-like 2.04165
RAD54L RAD54-like (S. cerevisiae) 2.0277
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 2.0276
PITX2 paired-like homeodomain 2 2.01375
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.00887

decreased expression

Symbol Name Standardized Value
VAT1 vesicle amine transport 1 -5.85115
USP6NL USP6 N-terminal like -5.43365
TLCD3A TLC domain containing 3A -4.88235
PECR peroxisomal trans-2-enoyl-CoA reductase -4.6301
MAP7 microtubule-associated protein 7 -4.54897
LDHD lactate dehydrogenase D -4.53295
ICAM3 intercellular adhesion molecule 3 -4.09735
ARID5B AT rich interactive domain 5B (MRF1-like) -4.01055
NR2F6 nuclear receptor subfamily 2, group F, member 6 -3.6998
TOR1A torsin family 1, member A (torsin A) -3.3657
CLIC4 chloride intracellular channel 4 -3.27887
CCNB2 cyclin B2 -3.2633
RNF167 ring finger protein 167 -3.07865
MALT1 MALT1 paracaspase -2.86598
AZGP1 alpha-2-glycoprotein 1, zinc-binding -2.80785
WASHC4 WASH complex subunit 4 -2.70258
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.6244
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.6177
PRR7 proline rich 7 (synaptic) -2.4288
CCNB1 cyclin B1 -2.3345
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -2.24605
TOP6BL TOP6B like initiator of meiotic double strand breaks -2.103
CPNE3 copine III -2.0367
DDA1 DET1 and DDB1 associated 1 -2.0152