CRCGN008_HEPG2_24H:B21 Gene Set
Genes
50 genes differentially expressed following the CRCGN008_HEPG2_24H:B21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHMP6
|
charged multivesicular body protein 6
|
10.0
|
|
CBR3
|
carbonyl reductase 3
|
5.23205
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
5.054
|
|
MYLK
|
myosin light chain kinase
|
4.74385
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.5975
|
|
ABHD6
|
abhydrolase domain containing 6
|
4.42152
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.32395
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.3155
|
|
EGF
|
epidermal growth factor
|
4.01265
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
3.88742
|
|
PTK2
|
protein tyrosine kinase 2
|
3.682
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
3.3192
|
|
NMU
|
neuromedin U
|
3.2419
|
|
ZNF318
|
zinc finger protein 318
|
3.14418
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
3.09415
|
|
CCNF
|
cyclin F
|
3.04645
|
|
CHN1
|
chimerin 1
|
2.9824
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.95905
|
|
ZNF589
|
zinc finger protein 589
|
2.89277
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.8517
|
|
TBP
|
TATA box binding protein
|
2.8482
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.82333
|
|
EPHA3
|
EPH receptor A3
|
2.65175
|
|
JADE2
|
jade family PHD finger 2
|
2.59775
|
|
CREG1
|
cellular repressor of E1A-stimulated genes 1
|
2.45425
|
|
METRN
|
meteorin, glial cell differentiation regulator
|
2.2257
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
2.1468
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.07595
|
|
MUL1
|
mitochondrial E3 ubiquitin protein ligase 1
|
2.01175
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
MAPK13
|
mitogen-activated protein kinase 13
|
-7.01323
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.73505
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-5.5426
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-5.29555
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-5.13795
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.83595
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.79145
|
|
CD58
|
CD58 molecule
|
-3.69943
|
|
CCNB2
|
cyclin B2
|
-3.304
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.27577
|
|
GLOD4
|
glyoxalase domain containing 4
|
-2.8296
|
|
CCNB1
|
cyclin B1
|
-2.60505
|
|
SOAT2
|
sterol O-acyltransferase 2
|
-2.5953
|
|
DCK
|
deoxycytidine kinase
|
-2.56885
|
|
KHDC4
|
KH domain containing 4, pre-mRNA splicing factor
|
-2.3841
|
|
WASHC4
|
WASH complex subunit 4
|
-2.38082
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.32205
|
|
MRFAP1L1
|
Morf4 family associated protein 1-like 1
|
-2.1566
|
|
MAGED2
|
melanoma antigen family D2
|
-2.1456
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
-2.1013
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-2.0133
|
