CRCGN008_HEPG2_24H:B22 Gene Set
Genes
51 genes differentially expressed following the CRCGN008_HEPG2_24H:B22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
6.1841
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
5.2451
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
4.8953
|
|
UBQLN2
|
ubiquilin 2
|
4.7608
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
4.75755
|
|
HOXA10
|
homeobox A10
|
4.35252
|
|
ABHD6
|
abhydrolase domain containing 6
|
4.2713
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.09415
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
4.08715
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.9327
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
3.55502
|
|
KLHL9
|
kelch-like family member 9
|
3.0943
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
3.04365
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.92937
|
|
PMM2
|
phosphomannomutase 2
|
2.8521
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.78433
|
|
JADE2
|
jade family PHD finger 2
|
2.76743
|
|
CYCS
|
cytochrome c, somatic
|
2.70345
|
|
EPHA3
|
EPH receptor A3
|
2.60562
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.4345
|
|
ECD
|
ecdysoneless homolog (Drosophila)
|
2.2414
|
|
KLHDC2
|
kelch domain containing 2
|
2.20305
|
|
OAS2
|
2'-5'-oligoadenylate synthetase 2, 69/71kDa
|
2.1565
|
|
NFIL3
|
nuclear factor, interleukin 3 regulated
|
2.1469
|
|
NLGN4Y
|
neuroligin 4, Y-linked
|
2.12355
|
|
TLR4
|
toll-like receptor 4
|
2.1139
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
2.1053
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.1032
|
|
SCRN1
|
secernin 1
|
2.08975
|
|
OSBPL10
|
oxysterol binding protein-like 10
|
2.08295
|
|
ZNF804A
|
zinc finger protein 804A
|
2.06395
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-5.6291
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.21825
|
|
ZNF586
|
zinc finger protein 586
|
-4.82255
|
|
HAT1
|
histone acetyltransferase 1
|
-4.68715
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-4.58762
|
|
LDHD
|
lactate dehydrogenase D
|
-4.45965
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-4.4524
|
|
FASTKD5
|
FAST kinase domains 5
|
-4.36405
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-4.23107
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-4.20595
|
|
ICAM3
|
intercellular adhesion molecule 3
|
-3.58395
|
|
CCNB2
|
cyclin B2
|
-3.39845
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.89985
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.86838
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.86205
|
|
EIF4EBP1
|
eukaryotic translation initiation factor 4E binding protein 1
|
-2.4868
|
|
ATF5
|
activating transcription factor 5
|
-2.44533
|
|
ZNF134
|
zinc finger protein 134
|
-2.1452
|
|
RNF167
|
ring finger protein 167
|
-2.063
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.00815
|
