| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2,4-dimethoxyaniline.hcl 2.52 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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79 genes differentially expressed following the CRCGN008_HEPG2_24H:B23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPATCH8 | G patch domain containing 8 | 5.36587 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.17435 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 5.06575 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 5.03785 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 5.00865 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 4.97475 |
| UBQLN2 | ubiquilin 2 | 4.8443 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.6899 |
| EGF | epidermal growth factor | 4.3147 |
| GPER1 | G protein-coupled estrogen receptor 1 | 4.08855 |
| PLSCR1 | phospholipid scramblase 1 | 3.58805 |
| PRR15L | proline rich 15-like | 3.58775 |
| LPAR2 | lysophosphatidic acid receptor 2 | 3.17918 |
| MAP7 | microtubule-associated protein 7 | 3.13685 |
| LCN2 | lipocalin 2 | 2.9556 |
| TRMT61B | tRNA methyltransferase 61B | 2.68505 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 2.6308 |
| CRTAP | cartilage associated protein | 2.6284 |
| PLSCR3 | phospholipid scramblase 3 | 2.61608 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.59025 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 2.5043 |
| POMGNT1 | protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) | 2.489 |
| ECD | ecdysoneless homolog (Drosophila) | 2.3866 |
| SMIM5 | small integral membrane protein 5 | 2.37433 |
| NMU | neuromedin U | 2.36405 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.3408 |
| KAT6A | K(lysine) acetyltransferase 6A | 2.2725 |
| SNRNP27 | small nuclear ribonucleoprotein 27kDa (U4/U6.U5) | 2.21217 |
| NRTN | neurturin | 2.165 |
| HBB | hemoglobin, beta | 2.13063 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 2.11345 |
| FASTK | Fas-activated serine/threonine kinase | 2.08337 |
| SRBD1 | S1 RNA binding domain 1 | 2.07335 |
| ACE2 | angiotensin I converting enzyme 2 | 2.07052 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 | 2.0346 |
| CLIC5 | chloride intracellular channel 5 | 2.0338 |
| IFNGR1 | interferon gamma receptor 1 | 2.02878 |
| DMAP1 | DNA methyltransferase 1 associated protein 1 | 2.01765 |
| MAP3K11 | mitogen-activated protein kinase kinase kinase 11 | 2.0129 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PLK1 | polo-like kinase 1 | -10.0 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -5.58595 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.3969 |
| NRIP1 | nuclear receptor interacting protein 1 | -5.14435 |
| DNM1L | dynamin 1-like | -4.88465 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.833 |
| ZNF586 | zinc finger protein 586 | -4.5094 |
| THAP11 | THAP domain containing 11 | -4.41605 |
| MAPK13 | mitogen-activated protein kinase 13 | -4.2853 |
| CCNB2 | cyclin B2 | -3.53035 |
| TWF2 | twinfilin actin binding protein 2 | -3.4054 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -3.26175 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.10495 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -3.02905 |
| RBM15B | RNA binding motif protein 15B | -2.9209 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.83145 |
| ATF5 | activating transcription factor 5 | -2.71907 |
| RGS2 | regulator of G-protein signaling 2 | -2.6088 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.53625 |
| CENPT | centromere protein T | -2.48585 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.47125 |
| TSKU | tsukushi, small leucine rich proteoglycan | -2.4374 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -2.40235 |
| CATSPERH | catsper channel auxiliary subunit eta | -2.3404 |
| MRPL37 | mitochondrial ribosomal protein L37 | -2.30005 |
| NUTF2 | nuclear transport factor 2 | -2.25185 |
| BST2 | bone marrow stromal cell antigen 2 | -2.2426 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | -2.2374 |
| CCNF | cyclin F | -2.23255 |
| RBFA | ribosome binding factor A (putative) | -2.2133 |
| ZNF556 | zinc finger protein 556 | -2.2132 |
| FOXL2 | forkhead box L2 | -2.1926 |
| TROAP | trophinin associated protein | -2.1862 |
| ZNF227 | zinc finger protein 227 | -2.15395 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 | -2.1168 |
| PTMS | parathymosin | -2.1072 |
| RESF1 | retroelement silencing factor 1 | -2.0895 |
| DUX4 | double homeobox 4 | -2.0779 |
| HOXC8 | homeobox C8 | -2.00205 |
| DCTN5 | dynactin 5 (p25) | -2.00025 |
