CRCGN008_HEPG2_24H:C01 Gene Set
Genes
48 genes differentially expressed following the CRCGN008_HEPG2_24H:C01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
5.41925
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
5.14405
|
|
MAMLD1
|
mastermind-like domain containing 1
|
4.92095
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.84945
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.2281
|
|
EGF
|
epidermal growth factor
|
3.8422
|
|
VGLL4
|
vestigial-like family member 4
|
3.53475
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.7981
|
|
MCM3
|
minichromosome maintenance complex component 3
|
2.76055
|
|
GPATCH8
|
G patch domain containing 8
|
2.63727
|
|
PEPD
|
peptidase D
|
2.47185
|
|
PKN1
|
protein kinase N1
|
2.4349
|
|
NFIL3
|
nuclear factor, interleukin 3 regulated
|
2.4004
|
|
ALG8
|
ALG8, alpha-1,3-glucosyltransferase
|
2.34305
|
|
MAP3K2
|
mitogen-activated protein kinase kinase kinase 2
|
2.3083
|
|
PIH1D1
|
PIH1 domain containing 1
|
2.2962
|
|
SNX6
|
sorting nexin 6
|
2.2221
|
|
TLR4
|
toll-like receptor 4
|
2.0723
|
|
FIBP
|
fibroblast growth factor (acidic) intracellular binding protein
|
2.0127
|
|
UCK2
|
uridine-cytidine kinase 2
|
2.00595
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-5.871
|
|
CD320
|
CD320 molecule
|
-4.7206
|
|
CCNB2
|
cyclin B2
|
-4.70205
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.40925
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-4.3014
|
|
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1
|
-4.26145
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-4.09505
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.95445
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.1939
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.13605
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.0105
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.93728
|
|
RNF167
|
ring finger protein 167
|
-2.8556
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.7349
|
|
SNX11
|
sorting nexin 11
|
-2.69307
|
|
BDH1
|
3-hydroxybutyrate dehydrogenase, type 1
|
-2.64475
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.54598
|
|
USP6NL
|
USP6 N-terminal like
|
-2.45115
|
|
POGLUT1
|
protein O-glucosyltransferase 1
|
-2.3621
|
|
TMEM248
|
transmembrane protein 248
|
-2.2537
|
|
CLDN5
|
claudin 5
|
-2.17395
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.14345
|
|
THBD
|
thrombomodulin
|
-2.13653
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.0978
|
|
CCDC71
|
coiled-coil domain containing 71
|
-2.0805
|
|
RHOF
|
ras homolog family member F (in filopodia)
|
-2.05125
|
|
SH2B2
|
SH2B adaptor protein 2
|
-2.0207
|
