| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | benzyl-alcohol 19.8 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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76 genes differentially expressed following the CRCGN008_HEPG2_24H:C02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 8.68535 |
| CHMP6 | charged multivesicular body protein 6 | 5.502 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.3587 |
| RPL39L | ribosomal protein L39-like | 5.0533 |
| MYLK | myosin light chain kinase | 5.03895 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.98065 |
| E2F2 | E2F transcription factor 2 | 4.9582 |
| CBR3 | carbonyl reductase 3 | 4.897 |
| ADRB2 | adrenoceptor beta 2, surface | 4.87875 |
| ATP11B | ATPase, class VI, type 11B | 4.51075 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 4.01322 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.6535 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 3.61565 |
| KLHL9 | kelch-like family member 9 | 3.58218 |
| HDGFL3 | HDGF like 3 | 3.53272 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 3.3709 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.1829 |
| EGF | epidermal growth factor | 3.12415 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.9493 |
| PRR15L | proline rich 15-like | 2.892 |
| PLSCR3 | phospholipid scramblase 3 | 2.8814 |
| MAP7 | microtubule-associated protein 7 | 2.76003 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.72003 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.60423 |
| TBC1D31 | TBC1 domain family, member 31 | 2.58315 |
| ZNF217 | zinc finger protein 217 | 2.42185 |
| CYCS | cytochrome c, somatic | 2.3066 |
| TNIP1 | TNFAIP3 interacting protein 1 | 2.2876 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 2.24137 |
| S100PBP | S100P binding protein | 2.18925 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.1751 |
| NUP43 | nucleoporin 43kDa | 2.1693 |
| TBP | TATA box binding protein | 2.1433 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | 2.12965 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.1102 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 2.1078 |
| PGAM4 | phosphoglycerate mutase family member 4 | 2.04535 |
| MB | myoglobin | 2.04285 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 | 2.0305 |
| MYBPC1 | myosin binding protein C, slow type | 2.02275 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -6.4055 |
| RAI14 | retinoic acid induced 14 | -5.4591 |
| NRIP1 | nuclear receptor interacting protein 1 | -5.25275 |
| CDC20 | cell division cycle 20 | -5.0 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.9701 |
| CD320 | CD320 molecule | -4.66275 |
| FASTKD5 | FAST kinase domains 5 | -4.6077 |
| ILK | integrin-linked kinase | -4.54145 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -3.99237 |
| CCNB2 | cyclin B2 | -3.94515 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -3.91515 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.89825 |
| RBM15B | RNA binding motif protein 15B | -3.1546 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.95883 |
| CCNB1 | cyclin B1 | -2.85995 |
| RAI2 | retinoic acid induced 2 | -2.76695 |
| SNX11 | sorting nexin 11 | -2.51368 |
| HSPA4 | heat shock 70kDa protein 4 | -2.40053 |
| TTI2 | TELO2 interacting protein 2 | -2.37225 |
| KDR | kinase insert domain receptor | -2.28125 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.27852 |
| MEP1B | meprin A, beta | -2.255 |
| PGAP4 | post-GPI attachment to proteins GalNAc transferase 4 | -2.2492 |
| MMRN2 | multimerin 2 | -2.2455 |
| CCNH | cyclin H | -2.232 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.1763 |
| RBM34 | RNA binding motif protein 34 | -2.1552 |
| REG1A | regenerating islet-derived 1 alpha | -2.1522 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -2.10895 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.08882 |
| NOTCH4 | notch 4 | -2.07995 |
| BMP4 | bone morphogenetic protein 4 | -2.05 |
| CBLIF | cobalamin binding intrinsic factor | -2.03875 |
| JADE3 | jade family PHD finger 3 | -2.03575 |
| H1-2 | H1.2 linker histone, cluster member | -2.0127 |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic | -2.0083 |
