| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | benzyl-alcohol 1.24 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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52 genes differentially expressed following the CRCGN008_HEPG2_24H:C06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PEX11A | peroxisomal biogenesis factor 11 alpha | 7.81042 |
| SQOR | sulfide quinone oxidoreductase | 5.43435 |
| ADRB2 | adrenoceptor beta 2, surface | 5.1647 |
| AMDHD2 | amidohydrolase domain containing 2 | 5.10345 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 4.8692 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.86285 |
| LOC122526780 | uncharacterized LOC122526780 | 4.7811 |
| PRR15L | proline rich 15-like | 4.62485 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.40195 |
| CCL2 | chemokine (C-C motif) ligand 2 | 4.1488 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.06733 |
| EGF | epidermal growth factor | 3.64945 |
| CEP57 | centrosomal protein 57kDa | 3.49801 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.725 |
| VGLL4 | vestigial-like family member 4 | 2.60217 |
| CYCS | cytochrome c, somatic | 2.5173 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.46315 |
| PPFIA2 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 | 2.32735 |
| OMD | osteomodulin | 2.3092 |
| EPHA3 | EPH receptor A3 | 2.30415 |
| PMM2 | phosphomannomutase 2 | 2.19105 |
| CCNG1 | cyclin G1 | 2.16365 |
| ANK2 | ankyrin 2, neuronal | 2.15415 |
| TLR4 | toll-like receptor 4 | 2.14485 |
| GAS2 | growth arrest-specific 2 | 2.06855 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.0205 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.0177 |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 | 2.0097 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 2.00163 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -5.0853 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -4.9156 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.44085 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.8813 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -3.16455 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.16265 |
| IFRD2 | interferon-related developmental regulator 2 | -2.76975 |
| SPAG4 | sperm associated antigen 4 | -2.66575 |
| TXNDC9 | thioredoxin domain containing 9 | -2.6636 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.65505 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.55525 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -2.4912 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.4532 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) | -2.3972 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.38985 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -2.344 |
| CLDN1 | claudin 1 | -2.2077 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 | -2.1757 |
| MAGT1 | magnesium transporter 1 | -2.13525 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 | -2.1342 |
| KLF1 | Kruppel-like factor 1 (erythroid) | -2.1267 |
| DNASE1L2 | deoxyribonuclease I-like 2 | -2.07955 |
| APOC1 | apolipoprotein C-I | -2.07723 |