CRCGN008_HEPG2_24H:C06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzyl-alcohol 1.24 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

52 genes differentially expressed following the CRCGN008_HEPG2_24H:C06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PEX11A peroxisomal biogenesis factor 11 alpha 7.81042
SQOR sulfide quinone oxidoreductase 5.43435
ADRB2 adrenoceptor beta 2, surface 5.1647
AMDHD2 amidohydrolase domain containing 2 5.10345
BACE2 beta-site APP-cleaving enzyme 2 4.8692
PPARG peroxisome proliferator-activated receptor gamma 4.86285
LOC122526780 uncharacterized LOC122526780 4.7811
PRR15L proline rich 15-like 4.62485
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.40195
CCL2 chemokine (C-C motif) ligand 2 4.1488
SNAP25 synaptosomal-associated protein, 25kDa 4.06733
EGF epidermal growth factor 3.64945
CEP57 centrosomal protein 57kDa 3.49801
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.725
VGLL4 vestigial-like family member 4 2.60217
CYCS cytochrome c, somatic 2.5173
GSTZ1 glutathione S-transferase zeta 1 2.46315
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 2.32735
OMD osteomodulin 2.3092
EPHA3 EPH receptor A3 2.30415
PMM2 phosphomannomutase 2 2.19105
CCNG1 cyclin G1 2.16365
ANK2 ankyrin 2, neuronal 2.15415
TLR4 toll-like receptor 4 2.14485
GAS2 growth arrest-specific 2 2.06855
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 2.0205
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.0177
RABEP1 rabaptin, RAB GTPase binding effector protein 1 2.0097
SPTAN1 spectrin, alpha, non-erythrocytic 1 2.00163

decreased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -5.0853
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -4.9156
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.44085
MAPK13 mitogen-activated protein kinase 13 -3.8813
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -3.16455
OXA1L oxidase (cytochrome c) assembly 1-like -3.16265
IFRD2 interferon-related developmental regulator 2 -2.76975
SPAG4 sperm associated antigen 4 -2.66575
TXNDC9 thioredoxin domain containing 9 -2.6636
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.65505
FOS FBJ murine osteosarcoma viral oncogene homolog -2.55525
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -2.4912
CASP7 caspase 7, apoptosis-related cysteine peptidase -2.4532
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -2.3972
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.38985
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) -2.344
CLDN1 claudin 1 -2.2077
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 -2.1757
MAGT1 magnesium transporter 1 -2.13525
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 -2.1342
KLF1 Kruppel-like factor 1 (erythroid) -2.1267
DNASE1L2 deoxyribonuclease I-like 2 -2.07955
APOC1 apolipoprotein C-I -2.07723