| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | bromodichloromethane 40.2 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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41 genes differentially expressed following the CRCGN008_HEPG2_24H:C13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.96135 |
| GSTZ1 | glutathione S-transferase zeta 1 | 5.26725 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.10555 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 5.0512 |
| ADRB2 | adrenoceptor beta 2, surface | 4.8057 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.4797 |
| CDCA4 | cell division cycle associated 4 | 4.317 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 3.41312 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.1551 |
| VGLL4 | vestigial-like family member 4 | 3.06298 |
| COPS7A | COP9 signalosome subunit 7A | 2.7911 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.57525 |
| TNIP1 | TNFAIP3 interacting protein 1 | 2.3814 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.36785 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.3062 |
| CORO1A | coronin, actin binding protein, 1A | 2.26185 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 2.12985 |
| STK16 | serine/threonine kinase 16 | 2.09155 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 2.0223 |
| Symbol | Name | Standardized Value |
|---|---|---|
| OXA1L | oxidase (cytochrome c) assembly 1-like | -6.3651 |
| LOC124907782 | dual specificity protein phosphatase 22 | -5.1248 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -4.99305 |
| LDHD | lactate dehydrogenase D | -4.91325 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.60245 |
| TLCD3A | TLC domain containing 3A | -4.57355 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.90035 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.67883 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.47495 |
| MTA1 | metastasis associated 1 | -3.4532 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -3.05197 |
| HSPA8 | heat shock 70kDa protein 8 | -2.9923 |
| WASHC4 | WASH complex subunit 4 | -2.9277 |
| RGS2 | regulator of G-protein signaling 2 | -2.7584 |
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase | -2.75415 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.4465 |
| CLIC4 | chloride intracellular channel 4 | -2.43227 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.42613 |
| UFD1 | ubiquitin recognition factor in ER associated degradation 1 | -2.2112 |
| ASPA | aspartoacylase | -2.0252 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | -2.02362 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.02 |
