CRCGN008_HEPG2_24H:C14 Gene Set
Genes
49 genes differentially expressed following the CRCGN008_HEPG2_24H:C14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CBR3
|
carbonyl reductase 3
|
10.0
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
5.6696
|
|
MOK
|
MOK protein kinase
|
4.9895
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
4.89055
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.4917
|
|
FZD7
|
frizzled class receptor 7
|
4.43635
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.41792
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.3147
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.2837
|
|
PLS1
|
plastin 1
|
3.17015
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.0833
|
|
NMU
|
neuromedin U
|
2.8971
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.89155
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
2.8689
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.7846
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
2.7529
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
2.64885
|
|
EPHA3
|
EPH receptor A3
|
2.53435
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
2.3515
|
|
CYCS
|
cytochrome c, somatic
|
2.3261
|
|
TLR4
|
toll-like receptor 4
|
2.2907
|
|
METRN
|
meteorin, glial cell differentiation regulator
|
2.2854
|
|
PSIP1
|
PC4 and SFRS1 interacting protein 1
|
2.23733
|
|
TBP
|
TATA box binding protein
|
2.05655
|
|
MAPKAPK2
|
mitogen-activated protein kinase-activated protein kinase 2
|
2.05318
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
FASTKD5
|
FAST kinase domains 5
|
-5.45145
|
|
CD320
|
CD320 molecule
|
-5.3876
|
|
TUBB6
|
tubulin, beta 6 class V
|
-5.33725
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.17355
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-5.108
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.9824
|
|
LDHD
|
lactate dehydrogenase D
|
-4.7957
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
-4.2833
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-4.1323
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.93945
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.8482
|
|
CCNB2
|
cyclin B2
|
-3.73305
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.6499
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-3.61595
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.3513
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.9251
|
|
SNX11
|
sorting nexin 11
|
-2.54128
|
|
CCNB1
|
cyclin B1
|
-2.52225
|
|
ERO1A
|
endoplasmic reticulum oxidoreductase 1 alpha
|
-2.5155
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.2978
|
|
SESN1
|
sestrin 1
|
-2.28695
|
|
REEP5
|
receptor accessory protein 5
|
-2.25222
|
|
LYRM1
|
LYR motif containing 1
|
-2.1951
|
|
PIGG
|
phosphatidylinositol glycan anchor biosynthesis, class G
|
-2.1178
|
