CRCGN008_HEPG2_24H:C19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description mitoxantrone 20.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

1419 genes differentially expressed following the CRCGN008_HEPG2_24H:C19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
BPHL biphenyl hydrolase-like (serine hydrolase) 10.0
HEBP1 heme binding protein 1 9.38145
PPP1R13B protein phosphatase 1, regulatory subunit 13B 8.51985
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 8.10495
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 7.9277
TESK1 testis-specific kinase 1 7.23885
UBE2L6 ubiquitin-conjugating enzyme E2L 6 7.0831
WDR7 WD repeat domain 7 7.02255
NR1H2 nuclear receptor subfamily 1, group H, member 2 6.6647
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 6.6255
MSRA methionine sulfoxide reductase A 6.5366
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 6.53085
TRAPPC6A trafficking protein particle complex 6A 6.4463
TMEM109 transmembrane protein 109 6.2334
FAIM Fas apoptotic inhibitory molecule 6.2047
GHR growth hormone receptor 5.9683
BAD BCL2-associated agonist of cell death 5.86028
ANO1 anoctamin 1, calcium activated chloride channel 5.74935
CAPN1 calpain 1, (mu/I) large subunit 5.675
SRC SRC proto-oncogene, non-receptor tyrosine kinase 5.65492
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 5.65067
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 5.6186
LPAR2 lysophosphatidic acid receptor 2 5.58047
TIMP2 TIMP metallopeptidase inhibitor 2 5.4256
UBQLN2 ubiquilin 2 5.4089
IFNAR1 interferon (alpha, beta and omega) receptor 1 5.33005
RTL8A retrotransposon Gag like 8A 5.2536
NPDC1 neural proliferation, differentiation and control, 1 5.2443
EPN2 epsin 2 5.16447
MCOLN1 mucolipin 1 5.12155
TSEN2 TSEN2 tRNA splicing endonuclease subunit 5.11845
CIAO3 cytosolic iron-sulfur assembly component 3 5.0858
IL1B interleukin 1, beta 5.02803
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 5.0239
ARL4C ADP-ribosylation factor-like 4C 5.00608
HTRA1 HtrA serine peptidase 1 4.9824
CHN1 chimerin 1 4.93925
ABHD4 abhydrolase domain containing 4 4.92475
NVL nuclear VCP-like 4.89645
EDN1 endothelin 1 4.8883
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 4.87575
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 4.687
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 4.66815
PGAP4 post-GPI attachment to proteins GalNAc transferase 4 4.6427
GPC1 glypican 1 4.64007
CORO1A coronin, actin binding protein, 1A 4.63525
CTSD cathepsin D 4.61385
PSENEN presenilin enhancer gamma secretase subunit 4.6121
LYN LYN proto-oncogene, Src family tyrosine kinase 4.61062
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 4.57545
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 4.57305
SMIM40 small integral membrane protein 40 4.5451
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 4.54405
DPH2 DPH2 homolog (S. cerevisiae) 4.5002
PTK2 protein tyrosine kinase 2 4.46985
CBR3 carbonyl reductase 3 4.46785
NOTCH1 notch 1 4.4596
TERT telomerase reverse transcriptase 4.45225
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 4.4285
SHB Src homology 2 domain containing adaptor protein B 4.4232
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 4.41875
SLITRK2 SLIT and NTRK-like family, member 2 4.32465
TMEM160 transmembrane protein 160 4.29425
RIPPLY2-CYB5R4 RIPPLY2-CYB5R4 readthrough 4.2922
PPARG peroxisome proliferator-activated receptor gamma 4.2893
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 4.2503
PRKX protein kinase, X-linked 4.2073
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 4.18915
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 4.16355
HLA-DMA major histocompatibility complex, class II, DM alpha 4.14785
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 4.13872
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 4.1145
SLC35B1 solute carrier family 35, member B1 4.1137
NGRN neugrin, neurite outgrowth associated 4.06435
GPR45 G protein-coupled receptor 45 4.042
VAC14 Vac14 homolog (S. cerevisiae) 4.03955
ACO1 aconitase 1, soluble 4.03805
GRIK4 glutamate receptor, ionotropic, kainate 4 4.01355
SH3D19 SH3 domain containing 19 4.01122
PPDPF pancreatic progenitor cell differentiation and proliferation factor 4.00685
CCDC85B coiled-coil domain containing 85B 4.0045
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 3.97725
MSANTD3-TMEFF1 MSANTD3-TMEFF1 readthrough 3.93547
ZNF219 zinc finger protein 219 3.90845
GDAP2 ganglioside induced differentiation associated protein 2 3.9058
GAA glucosidase, alpha; acid 3.89335
SLC17A4 solute carrier family 17, member 4 3.8716
RSU1 Ras suppressor protein 1 3.84825
AFAP1 actin filament associated protein 1 3.8422
TMEM212 transmembrane protein 212 3.83715
GFOD1 glucose-fructose oxidoreductase domain containing 1 3.8353
FAM204A family with sequence similarity 204, member A 3.8344
IFT54 intraflagellar transport 54 3.82145
FABP6 fatty acid binding protein 6, ileal 3.82
OTUD7B OTU deubiquitinase 7B 3.7957
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 3.7914
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 3.7632
EML3 echinoderm microtubule associated protein like 3 3.7621
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 3.7619
PRR15L proline rich 15-like 3.76105
ECH1 enoyl CoA hydratase 1, peroxisomal 3.75055
PLA2G2F phospholipase A2, group IIF 3.7401
NCS1 neuronal calcium sensor 1 3.74005
RAB21 RAB21, member RAS oncogene family 3.73855
ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough 3.72385
ARL2 ADP-ribosylation factor-like 2 3.70905
LSR lipolysis stimulated lipoprotein receptor 3.6854
SORCS3 sortilin-related VPS10 domain containing receptor 3 3.674
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 3.66885
CNGA1 cyclic nucleotide gated channel alpha 1 3.6647
SIX3 SIX homeobox 3 3.66215
PCLO piccolo presynaptic cytomatrix protein 3.6609
CEP162 centrosomal protein 162kDa 3.65933
NOSIP nitric oxide synthase interacting protein 3.6575
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 3.6453
NKAIN1 Na+/K+ transporting ATPase interacting 1 3.63435
RPGRIP1L RPGRIP1-like 3.63025
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) 3.6273
ADGRG1 adhesion G protein-coupled receptor G1 3.61795
MAGIX MAGI family member, X-linked 3.61585
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 3.6141
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28 3.6128
CIAO2B cytosolic iron-sulfur assembly component 2B 3.6079
MYLK myosin light chain kinase 3.60135
RIDA reactive intermediate imine deaminase A homolog 3.58365
FLT4 fms-related tyrosine kinase 4 3.57665
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 3.57193
ERI3 ERI1 exoribonuclease family member 3 3.56845
FGFR2 fibroblast growth factor receptor 2 3.56114
MMP2 matrix metallopeptidase 2 3.56
IMPACT impact RWD domain protein 3.5532
DLK2 delta-like 2 homolog (Drosophila) 3.54925
KIAA0408 KIAA0408 3.5409
PAX2 paired box 2 3.53725
SCRN3 secernin 3 3.5355
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 3.53431
ARL3 ADP-ribosylation factor-like 3 3.53315
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 3.5294
SLC26A4 solute carrier family 26 (anion exchanger), member 4 3.5287
PLCH2 phospholipase C, eta 2 3.52665
SQOR sulfide quinone oxidoreductase 3.5261
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 3.52273
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 3.51855
SYN3 synapsin III 3.51705
FGD1 FYVE, RhoGEF and PH domain containing 1 3.5123
CD40 CD40 molecule, TNF receptor superfamily member 5 3.5083
RAI14 retinoic acid induced 14 3.5077
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6 3.50165
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 3.4931
IFT74 intraflagellar transport 74 3.49085
VAMP7 vesicle-associated membrane protein 7 3.48865
IGFBP3 insulin-like growth factor binding protein 3 3.48775
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 3.487
MMP15 matrix metallopeptidase 15 (membrane-inserted) 3.48565
PLAAT1 phospholipase A and acyltransferase 1 3.48475
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 3.4755
NMU neuromedin U 3.4709
PHKA1 phosphorylase kinase, alpha 1 (muscle) 3.4683
PSME3IP1 proteasome activator subunit 3 interacting protein 1 3.46825
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 3.46493
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 3.4585
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 3.45847
EFR3B EFR3 homolog B (S. cerevisiae) 3.45805
CIB2 calcium and integrin binding family member 2 3.45775
PAX8 paired box 8 3.44814
SULF1 sulfatase 1 3.44053
GRHL2 grainyhead-like 2 (Drosophila) 3.43595
FAM246A family with sequence similarity 246 member A 3.4339
LUZP2 leucine zipper protein 2 3.42985
RIC3 RIC3 acetylcholine receptor chaperone 3.41675
HPSE heparanase 3.412
THOC6 THO complex 6 3.4061
TSPAN12 tetraspanin 12 3.4023
MYH15 myosin, heavy chain 15 3.39315
PAQR5 progestin and adipoQ receptor family member V 3.3864
DNAH6 dynein, axonemal, heavy chain 6 3.3816
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 3.37815
TNIP1 TNFAIP3 interacting protein 1 3.3768
IQCK IQ motif containing K 3.37595
CHAD chondroadherin 3.37215
GUCA2B guanylate cyclase activator 2B (uroguanylin) 3.3667
ADRA2C adrenoceptor alpha 2C 3.3664
RNLS renalase, FAD-dependent amine oxidase 3.362
KIAA0930 KIAA0930 3.3563
CAPN5 calpain 5 3.35105
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 3.34983
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 3.3431
PLAAT2 phospholipase A and acyltransferase 2 3.3429
FBXO7 F-box protein 7 3.3389
STMN3 stathmin-like 3 3.33725
MTNR1A melatonin receptor 1A 3.33485
LRRC19 leucine rich repeat containing 19 3.33425
DAPL1 death associated protein-like 1 3.33135
EFCAB6 EF-hand calcium binding domain 6 3.33055
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 3.32926
RGCC regulator of cell cycle 3.32775
METTL8 methyltransferase like 8 3.31655
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 3.31635
ZNF804A zinc finger protein 804A 3.3154
ICAM5 intercellular adhesion molecule 5, telencephalin 3.3131
GPR50 G protein-coupled receptor 50 3.3099
RIN1 Ras and Rab interactor 1 3.3082
GRM5 glutamate receptor, metabotropic 5 3.30605
MTIF2 mitochondrial translational initiation factor 2 3.3022
NR2F6 nuclear receptor subfamily 2, group F, member 6 3.302
CNTNAP3B contactin associated protein-like 3B 3.29475
DGCR6L DiGeorge syndrome critical region gene 6-like 3.29445
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 3.2941
KIAA1549L KIAA1549-like 3.2907
DNAI4 dynein axonemal intermediate chain 4 3.29035
SYNPO synaptopodin 3.2865
NUCB1 nucleobindin 1 3.27242
DPYSL3 dihydropyrimidinase-like 3 3.27017
CCL2 chemokine (C-C motif) ligand 2 3.26915
ADTRP androgen-dependent TFPI-regulating protein 3.26895
NQO2 NAD(P)H dehydrogenase, quinone 2 3.2677
ALG3 ALG3, alpha-1,3- mannosyltransferase 3.267
GAS6 growth arrest-specific 6 3.2606
RIMS1 regulating synaptic membrane exocytosis 1 3.25965
ACKR2 atypical chemokine receptor 2 3.2578
TMEM158 transmembrane protein 158 (gene/pseudogene) 3.25645
RGL4 ral guanine nucleotide dissociation stimulator-like 4 3.2476
GRM7 glutamate receptor, metabotropic 7 3.24388
TEX13A testis expressed 13A 3.243
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 3.24065
PCOLCE2 procollagen C-endopeptidase enhancer 2 3.23145
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 3.22985
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 3.22787
CYCS cytochrome c, somatic 3.2249
NPHP1 nephronophthisis 1 (juvenile) 3.22345
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 3.2176
PTK2B protein tyrosine kinase 2 beta 3.20825
DGAT1 diacylglycerol O-acyltransferase 1 3.20465
FEZF2 FEZ family zinc finger 2 3.2027
ZIC4 Zic family member 4 3.1974
TKTL1 transketolase-like 1 3.1965
COL7A1 collagen, type VII, alpha 1 3.19543
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 3.1949
CTNND1 catenin (cadherin-associated protein), delta 1 3.19405
SCN4A sodium channel, voltage gated, type IV alpha subunit 3.1902
ATP11B ATPase, class VI, type 11B 3.1893
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 3.1884
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 3.18795
TMEM156 transmembrane protein 156 3.1874
NIPAL3 NIPA-like domain containing 3 3.18677
MEP1B meprin A, beta 3.1861
EPHA3 EPH receptor A3 3.18568
KCNIP1 Kv channel interacting protein 1 3.1812
TSC22D3 TSC22 domain family, member 3 3.17855
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 3.17707
MMRN2 multimerin 2 3.1703
PBOV1 prostate and breast cancer overexpressed 1 3.16735
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) 3.1611
WASHC5 WASH complex subunit 5 3.16075
TRDMT1 tRNA aspartic acid methyltransferase 1 3.1604
BRINP1 bone morphogenetic protein/retinoic acid inducible neural-specific 1 3.1562
DAPK2 death-associated protein kinase 2 3.1518
TBX6 T-box 6 3.1518
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) 3.15025
MECR mitochondrial trans-2-enoyl-CoA reductase 3.1491
RND3 Rho family GTPase 3 3.14775
NSD1 nuclear receptor binding SET domain protein 1 3.14725
ATOH1 atonal homolog 1 (Drosophila) 3.1461
FGF23 fibroblast growth factor 23 3.14455
HSF1 heat shock transcription factor 1 3.14407
TBC1D30 TBC1 domain family, member 30 3.14247
LPAR3 lysophosphatidic acid receptor 3 3.1422
CAB39L calcium binding protein 39-like 3.1414
TMEM40 transmembrane protein 40 3.1399
ACVRL1 activin A receptor type II-like 1 3.135
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 3.13435
ISYNA1 inositol-3-phosphate synthase 1 3.1315
FABP2 fatty acid binding protein 2, intestinal 3.1291
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 3.1256
CTSO cathepsin O 3.12375
ZNF682 zinc finger protein 682 3.12325
HOXC10 homeobox C10 3.11975
SHARPIN SHANK-associated RH domain interactor 3.11745
CLDN14 claudin 14 3.117
RAB43 RAB43, member RAS oncogene family 3.11592
PSG4 pregnancy specific beta-1-glycoprotein 4 3.11586
EXT1 exostosin glycosyltransferase 1 3.11083
POU6F1 POU class 6 homeobox 1 3.10998
WDTC1 WD and tetratricopeptide repeats 1 3.1089
TRADD TNFRSF1A-associated via death domain 3.10547
RRAGA Ras-related GTP binding A 3.104
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 3.1029
YPEL5 yippee-like 5 (Drosophila) 3.10235
TLR3 toll-like receptor 3 3.10185
IFT22 intraflagellar transport 22 3.1018
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 3.10035
GPR85 G protein-coupled receptor 85 3.10015
CUBN cubilin (intrinsic factor-cobalamin receptor) 3.0966
MTFR1 mitochondrial fission regulator 1 3.0926
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 3.09215
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 3.0901
KIF26B kinesin family member 26B 3.0891
TAS2R4 taste receptor, type 2, member 4 3.08545
MOCS1 molybdenum cofactor synthesis 1 3.0845
CAV2 caveolin 2 3.08257
HSPB3 heat shock 27kDa protein 3 3.08205
SDF4 stromal cell derived factor 4 3.08017
STYK1 serine/threonine/tyrosine kinase 1 3.07872
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17 3.0785
DSCC1 DNA replication and sister chromatid cohesion 1 3.07705
CUEDC1 CUE domain containing 1 3.0751
HSPB1 heat shock 27kDa protein 1 3.07375
CTBP2 C-terminal binding protein 2 3.07195
STX4 syntaxin 4 3.07185
PTPRK protein tyrosine phosphatase, receptor type, K 3.07075
CLPTM1 cleft lip and palate associated transmembrane protein 1 3.069
PEX7 peroxisomal biogenesis factor 7 3.0687
CSPG4 chondroitin sulfate proteoglycan 4 3.06865
CMC4 C-x(9)-C motif containing 4 3.0678
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 3.06625
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 3.0659
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 3.0658
ARL2BP ADP-ribosylation factor-like 2 binding protein 3.0649
OR1A1 olfactory receptor, family 1, subfamily A, member 1 3.064
KLF8 Kruppel-like factor 8 3.0634
RNF44 ring finger protein 44 3.06185
GDAP1 ganglioside induced differentiation associated protein 1 3.06075
TMLHE trimethyllysine hydroxylase, epsilon 3.05855
PRDM9 PR domain containing 9 3.0565
ZNF132 zinc finger protein 132 3.05645
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 3.0492
SDC3 syndecan 3 3.04735
DUOX1 dual oxidase 1 3.0468
NCAN neurocan 3.0451
CA10 carbonic anhydrase X 3.03785
SNX7 sorting nexin 7 3.03665
ERCC5 excision repair cross-complementation group 5 3.0348
GSTA1 glutathione S-transferase alpha 1 3.02765
GET1 guided entry of tail-anchored proteins factor 1 3.02745
CALB2 calbindin 2 3.02135
PRH1-TAS2R14 PRH1-TAS2R14 readthrough 3.01865
METTL2A methyltransferase like 2A 3.01547
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase) 3.0147
CES2 carboxylesterase 2 3.01393
ITM2C integral membrane protein 2C 3.0112
CA4 carbonic anhydrase IV 3.0104
PDE5A phosphodiesterase 5A, cGMP-specific 3.0092
SCN3B sodium channel, voltage gated, type III beta subunit 3.00845
CENPI centromere protein I 3.00837
H2BC21 H2B clustered histone 21 3.0076
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) 3.00695
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 3.00593
BNC1 basonuclin 1 3.0059
UST uronyl-2-sulfotransferase 3.00472
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 2.99955
PSIP1 PC4 and SFRS1 interacting protein 1 2.99618
SOX2 SRY (sex determining region Y)-box 2 2.99455
SEPTIN5 septin 5 2.9935
MEGF6 multiple EGF-like-domains 6 2.99285
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 2.99245
COXFA4L2 cytochrome c oxidase hypoxia associated subunit FA4L2 2.99235
DOCK3 dedicator of cytokinesis 3 2.9856
VIM vimentin 2.9848
MOSPD3 motile sperm domain containing 3 2.9844
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.98242
EXOSC5 exosome component 5 2.9804
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) 2.97985
ISOC1 isochorismatase domain containing 1 2.97985
FOXH1 forkhead box H1 2.97855
TFDP3 transcription factor Dp family, member 3 2.97435
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 2.97392
FIG4 FIG4 phosphoinositide 5-phosphatase 2.9728
TRPV5 transient receptor potential cation channel, subfamily V, member 5 2.9726
ANO2 anoctamin 2, calcium activated chloride channel 2.97085
INA internexin neuronal intermediate filament protein, alpha 2.97065
KDM4D lysine (K)-specific demethylase 4D 2.96825
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 2.9642
BEST2 bestrophin 2 2.96
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 2.95715
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 2.95653
AP1G2 adaptor-related protein complex 1, gamma 2 subunit 2.95552
PRKN parkin RBR E3 ubiquitin protein ligase 2.9547
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 2.95145
KRTAP5-3 keratin associated protein 5-3 2.9504
RAMP2 receptor (G protein-coupled) activity modifying protein 2 2.9484
MAP6D1 MAP6 domain containing 1 2.94625
OR7C2 olfactory receptor, family 7, subfamily C, member 2 2.94305
ACTL6B actin-like 6B 2.93855
TMEM14B transmembrane protein 14B 2.9376
SH2D3A SH2 domain containing 3A 2.93757
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 2.93745
CD44 CD44 molecule (Indian blood group) 2.93581
IFNA6 interferon, alpha 6 2.9358
SOX12 SRY (sex determining region Y)-box 12 2.9356
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 2.9339
ASXL3 additional sex combs like transcriptional regulator 3 2.93165
MYO1D myosin ID 2.93115
DNAH7 dynein, axonemal, heavy chain 7 2.9304
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.9293
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 2.92395
TMEM132A transmembrane protein 132A 2.9238
CYB5R3 cytochrome b5 reductase 3 2.92145
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.91703
CREG1 cellular repressor of E1A-stimulated genes 1 2.91685
TRIM46 tripartite motif containing 46 2.9149
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) 2.9145
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 2.9144
TOMM34 translocase of outer mitochondrial membrane 34 2.91425
SAMD14 sterile alpha motif domain containing 14 2.9126
CCDC106 coiled-coil domain containing 106 2.91075
SIPA1L3 signal-induced proliferation-associated 1 like 3 2.91035
COTL1 coactosin-like F-actin binding protein 1 2.9099
LRRTM4 leucine rich repeat transmembrane neuronal 4 2.90885
FLT1 fms-related tyrosine kinase 1 2.90693
RTN2 reticulon 2 2.90627
EN1 engrailed homeobox 1 2.90275
BAG1 BCL2-associated athanogene 2.90177
RARG retinoic acid receptor, gamma 2.90055
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25 2.8987
NBEA neurobeachin 2.89715
CD200R1 CD200 receptor 1 2.8959
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 2.89475
NUCB2 nucleobindin 2 2.8918
GJA8 gap junction protein, alpha 8, 50kDa 2.888
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 2.88755
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 2.88625
RMC1 regulator of MON1-CCZ1 2.8851
HOXA2 homeobox A2 2.88405
ZNF532 zinc finger protein 532 2.88035
TLN2 talin 2 2.8778
SLC35F6 solute carrier family 35, member F6 2.8769
GRTP1 growth hormone regulated TBC protein 1 2.87645
RFX3 regulatory factor X, 3 (influences HLA class II expression) 2.8744
RBKS ribokinase 2.87227
PNPLA2 patatin-like phospholipase domain containing 2 2.8717
OXCT1 3-oxoacid CoA transferase 1 2.8699
DHRS7B dehydrogenase/reductase (SDR family) member 7B 2.8688
DPF1 D4, zinc and double PHD fingers family 1 2.8654
BMP8B bone morphogenetic protein 8b 2.8642
PLA2R1 phospholipase A2 receptor 1, 180kDa 2.86175
GTF2A1 general transcription factor IIA, 1, 19/37kDa 2.8617
EPS8L1 EPS8-like 1 2.85931
MOB3B MOB kinase activator 3B 2.85575
CCL7 chemokine (C-C motif) ligand 7 2.8545
ANGPTL2 angiopoietin-like 2 2.85333
SOX18 SRY (sex determining region Y)-box 18 2.85325
OLIG2 oligodendrocyte lineage transcription factor 2 2.84928
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35 2.8459
CLEC4M C-type lectin domain family 4, member M 2.84402
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 2.84245
POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3 2.84188
IPO13 importin 13 2.8418
UNC13A unc-13 homolog A (C. elegans) 2.8416
FRRS1L ferric-chelate reductase 1-like 2.8407
DOCK5 dedicator of cytokinesis 5 2.84005
KCNK10 potassium channel, two pore domain subfamily K, member 10 2.8393
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 2.839
SCARF1 scavenger receptor class F, member 1 2.8338
SLC2A4RG SLC2A4 regulator 2.83305
TBX1 T-box 1 2.82957
CDH12 cadherin 12, type 2 (N-cadherin 2) 2.82865
ST7L suppression of tumorigenicity 7 like 2.8282
SCAP SREBF chaperone 2.82545
IMPG1 interphotoreceptor matrix proteoglycan 1 2.82465
IFNA5 interferon, alpha 5 2.8242
AP3B2 adaptor-related protein complex 3, beta 2 subunit 2.82405
BABAM2 BRISC and BRCA1 A complex member 2 2.82403
MARK4 MAP/microtubule affinity-regulating kinase 4 2.8237
ANGPTL3 angiopoietin-like 3 2.82235
TDRD3 tudor domain containing 3 2.8221
ACOT13 acyl-CoA thioesterase 13 2.822
ZNF234 zinc finger protein 234 2.822
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 2.8218
ACVR2A activin A receptor, type IIA 2.821
CCDC25 coiled-coil domain containing 25 2.8192
LRRK1 leucine-rich repeat kinase 1 2.81905
WNT7B wingless-type MMTV integration site family, member 7B 2.8177
LRRC8E leucine rich repeat containing 8 family, member E 2.8156
SIRT5 sirtuin 5 2.8153
LOXL1 lysyl oxidase-like 1 2.81415
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa 2.81352
KATNB1 katanin p80 (WD repeat containing) subunit B 1 2.81327
MLF2 myeloid leukemia factor 2 2.81165
CPLX2 complexin 2 2.811
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) 2.8093
GPM6A glycoprotein M6A 2.80585
FSHR follicle stimulating hormone receptor 2.8058
MFF mitochondrial fission factor 2.8046
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 2.8046
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 2.80235
GALNS galactosamine (N-acetyl)-6-sulfatase 2.80165
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.8014
OSBPL1A oxysterol binding protein-like 1A 2.8002
VASP vasodilator-stimulated phosphoprotein 2.8002
IKZF4 IKAROS family zinc finger 4 (Eos) 2.79995
GRM8 glutamate receptor, metabotropic 8 2.79827
LOC128966622 putative protein N-methyltransferase FAM86B2 2.7977
WNT8B wingless-type MMTV integration site family, member 8B 2.79655
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1 2.79615
EPN3 epsin 3 2.79415
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 2.7903
DGKI diacylglycerol kinase, iota 2.79005
NNAT neuronatin 2.79
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 2.78885
FMNL3 formin-like 3 2.78875
LTB lymphotoxin beta (TNF superfamily, member 3) 2.7882
HAO2 hydroxyacid oxidase 2 (long chain) 2.7878
BZW2 basic leucine zipper and W2 domains 2 2.78735
PTMS parathymosin 2.7873
CREB3L2 cAMP responsive element binding protein 3-like 2 2.7872
SYNC syncoilin, intermediate filament protein 2.7866
ACAD10 acyl-CoA dehydrogenase family, member 10 2.78625
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 2.7854
ADI1 acireductone dioxygenase 1 2.7851
GJA4 gap junction protein, alpha 4, 37kDa 2.7847
H1-5 H1.5 linker histone, cluster member 2.7838
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 2.7833
RASL11B RAS-like, family 11, member B 2.7828
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11 2.78185
RRAGB Ras-related GTP binding B 2.78165
CDHR5 cadherin-related family member 5 2.77838
MAGEB3 melanoma antigen family B3 2.7776
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 2.77635
GDF7 growth differentiation factor 7 2.77615
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 2.77535
SRI sorcin 2.77528
CLCA1 chloride channel accessory 1 2.7708
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 2.77025
GSTZ1 glutathione S-transferase zeta 1 2.76845
ARAF A-Raf proto-oncogene, serine/threonine kinase 2.76745
MARK1 MAP/microtubule affinity-regulating kinase 1 2.7651
GPC5 glypican 5 2.76505
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 2.76495
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 2.7642
TAS2R9 taste receptor, type 2, member 9 2.7611
ITSN1 intersectin 1 (SH3 domain protein) 2.76046
PLCE1 phospholipase C, epsilon 1 2.76008
JCAD junctional cadherin 5 associated 2.75845
ANTKMT adenine nucleotide translocase lysine methyltransferase 2.7583
CNTN5 contactin 5 2.7573
WDR25 WD repeat domain 25 2.75405
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 2.7526
MSMB microseminoprotein, beta- 2.7525
IL3RA interleukin 3 receptor, alpha (low affinity) 2.75225
DACH1 dachshund family transcription factor 1 2.75215
NIPSNAP3B nipsnap homolog 3B (C. elegans) 2.752
SIM1 single-minded family bHLH transcription factor 1 2.7509
FGFR4 fibroblast growth factor receptor 4 2.74865
GLP2R glucagon-like peptide 2 receptor 2.7457
PRKG2 protein kinase, cGMP-dependent, type II 2.7455
CD5L CD5 molecule-like 2.7427
CAPN9 calpain 9 2.73892
CDH10 cadherin 10, type 2 (T2-cadherin) 2.7387
MAMLD1 mastermind-like domain containing 1 2.73795
NPVF neuropeptide VF precursor 2.73775
AMDHD2 amidohydrolase domain containing 2 2.7323
EML1 echinoderm microtubule associated protein like 1 2.73185
TPP2 tripeptidyl peptidase II 2.73177
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 2.7308
ARMH3 armadillo like helical domain containing 3 2.72992
MARCHF2 membrane associated ring-CH-type finger 2 2.729
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor 2.72785
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 2.72685
HNF4G hepatocyte nuclear factor 4, gamma 2.72645
ZNF157 zinc finger protein 157 2.72635
TAS2R7 taste receptor, type 2, member 7 2.7263
MGAT4C MGAT4 family, member C 2.72595
CNGB3 cyclic nucleotide gated channel beta 3 2.72515
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 2.7235
TNR tenascin R 2.72275
TPMT thiopurine S-methyltransferase 2.72248
SLC22A17 solute carrier family 22, member 17 2.7218
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 2.72135
ZNF395 zinc finger protein 395 2.72053
RPA3 replication protein A3, 14kDa 2.71985
RTL8C retrotransposon Gag like 8C 2.7197
LHCGR luteinizing hormone/choriogonadotropin receptor 2.71955
TENM3 teneurin transmembrane protein 3 2.71875
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 2.71865
TEDC2 tubulin epsilon and delta complex 2 2.71775
HPCAL1 hippocalcin-like 1 2.71732
PBX1 pre-B-cell leukemia homeobox 1 2.71593
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 2.7156
PTPRS protein tyrosine phosphatase, receptor type, S 2.71415
FANCG Fanconi anemia, complementation group G 2.71405
ARHGAP28 Rho GTPase activating protein 28 2.7139
F8A2 coagulation factor VIII-associated 2 2.71205
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 2.71168
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 2.71035
FAM153A family with sequence similarity 153, member A 2.70803
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 2.70705
DNM2 dynamin 2 2.7063
FOXD2 forkhead box D2 2.70605
ZNF358 zinc finger protein 358 2.7031
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough 2.7012
GTF3A general transcription factor IIIA 2.7005
SMIM41 small integral membrane protein 41 2.7
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 2.69913
TMEM35A transmembrane protein 35A 2.6978
PSG11 pregnancy specific beta-1-glycoprotein 11 2.6932
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 2.69225
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 2.6919
RBMS2 RNA binding motif, single stranded interacting protein 2 2.69147
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 2.68725
ETHE1 ethylmalonic encephalopathy 1 2.68585
GRB7 growth factor receptor-bound protein 7 2.6857
GPR137 G protein-coupled receptor 137 2.682
EDN2 endothelin 2 2.68195
PSG2 pregnancy specific beta-1-glycoprotein 2 2.68155
COLEC10 collectin sub-family member 10 (C-type lectin) 2.6809
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 2.6802
MAPK10 mitogen-activated protein kinase 10 2.68
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 2.6768
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 2.67645
AQP7 aquaporin 7 2.6757
AMELX amelogenin, X-linked 2.6756
MRAS muscle RAS oncogene homolog 2.67475
GBX2 gastrulation brain homeobox 2 2.67425
POU6F2 POU class 6 homeobox 2 2.67345
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 2.67345
ZFR2 zinc finger RNA binding protein 2 2.6706
TMEM39B transmembrane protein 39B 2.66925
STON1 stonin 1 2.66765
LGALS12 lectin, galactoside-binding, soluble, 12 2.6676
P3H2 prolyl 3-hydroxylase 2 2.6672
RAD21L1 RAD21-like 1 (S. pombe) 2.6644
S1PR2 sphingosine-1-phosphate receptor 2 2.6633
ITFG1 integrin alpha FG-GAP repeat containing 1 2.6625
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa 2.66175
HRAS Harvey rat sarcoma viral oncogene homolog 2.66055
RPGR retinitis pigmentosa GTPase regulator 2.66005
ASTN2 astrotactin 2 2.65855
KRTAP9-9 keratin associated protein 9-9 2.6575
PERP PERP, TP53 apoptosis effector 2.6523
TCEA2 transcription elongation factor A (SII), 2 2.65225
CGRRF1 cell growth regulator with ring finger domain 1 2.64935
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 2.64405
FBXO40 F-box protein 40 2.6438
GNAT3 guanine nucleotide binding protein, alpha transducing 3 2.64315
RIMBP2 RIMS binding protein 2 2.64315
TJP3 tight junction protein 3 2.64155
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus 2.6415
TES testin LIM domain protein 2.6406
ZBTB7C zinc finger and BTB domain containing 7C 2.6403
PROCR protein C receptor, endothelial 2.6384
TRAPPC9 trafficking protein particle complex 9 2.63677
TXNL4A thioredoxin-like 4A 2.6356
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 2.63412
PRKCI protein kinase C, iota 2.6327
ARHGAP8 Rho GTPase activating protein 8 2.63242
LINC02854 long intergenic non-protein coding RNA 2854 2.632
ECM2 extracellular matrix protein 2, female organ and adipocyte specific 2.63185
OLFML1 olfactomedin-like 1 2.63015
DCX doublecortin 2.62948
SHISAL1 shisa like 1 2.6254
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 2.62463
LRRC15 leucine rich repeat containing 15 2.6244
BTC betacellulin 2.62365
ESRP2 epithelial splicing regulatory protein 2 2.62365
ELAC1 elaC ribonuclease Z 1 2.62315
BAMBI BMP and activin membrane-bound inhibitor 2.6213
CDK4 cyclin-dependent kinase 4 2.61715
TAS2R16 taste receptor, type 2, member 16 2.6109
FGF5 fibroblast growth factor 5 2.60887
KNL1 kinetochore scaffold 1 2.60855
TPD52-MRPS28 TPD52-MRPS28 readthrough 2.60518
NHLRC2 NHL repeat containing 2 2.60515
FGF12 fibroblast growth factor 12 2.60407
MCM3 minichromosome maintenance complex component 3 2.6035
NELL1 NEL-like 1 (chicken) 2.6031
LDOC1 leucine zipper, down-regulated in cancer 1 2.60295
MAOA monoamine oxidase A 2.60262
NMBR neuromedin B receptor 2.6026
STK10 serine/threonine kinase 10 2.60192
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 2.6019
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 2.6012
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 2.60045
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.60025
CCDC121 coiled-coil domain containing 121 2.59875
GJD2 gap junction protein, delta 2, 36kDa 2.59865
YIPF4 Yip1 domain family, member 4 2.59765
RASAL2 RAS protein activator like 2 2.5971
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 2.59705
BICRA BRD4 interacting chromatin remodeling complex associated protein 2.5947
GPRASP1 G protein-coupled receptor associated sorting protein 1 2.59425
NHLH2 nescient helix loop helix 2 2.59397
ZNF260 zinc finger protein 260 2.59278
PGAP6 post-GPI attachment to proteins 6 2.591
PFN2 profilin 2 2.59095
PHC1 polyhomeotic homolog 1 (Drosophila) 2.59025
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20 2.58835
SLC6A16 solute carrier family 6, member 16 2.58575
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) 2.5853
TNNT3 troponin T type 3 (skeletal, fast) 2.58475
PNOC prepronociceptin 2.58235
EYA3 EYA transcriptional coactivator and phosphatase 3 2.5821
CEP72 centrosomal protein 72kDa 2.58115
GFUS GDP-L-fucose synthase 2.58098
PRDM14 PR domain containing 14 2.57955
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.57935
SPIDR scaffolding protein involved in DNA repair 2.5791
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 2.57893
KRT3 keratin 3, type II 2.5778
AGK acylglycerol kinase 2.57615
PILRA paired immunoglobin-like type 2 receptor alpha 2.57592
REG1B regenerating islet-derived 1 beta 2.5757
OR2B2 olfactory receptor, family 2, subfamily B, member 2 2.57455
SNX13 sorting nexin 13 2.5736
TRIM39-RPP21 TRIM39-RPP21 readthrough 2.57325
CYSLTR1 cysteinyl leukotriene receptor 1 2.5724
HHLA2 HERV-H LTR-associating 2 2.5719
GPR153 G protein-coupled receptor 153 2.57167
CLXN calaxin 2.57115
LRFN3 leucine rich repeat and fibronectin type III domain containing 3 2.5695
SYNJ2BP synaptojanin 2 binding protein 2.5687
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 2.5677
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 2.56638
ZNF362 zinc finger protein 362 2.5647
LGMN legumain 2.56255
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 2.56215
CAMKMT calmodulin-lysine N-methyltransferase 2.5617
H1-10 H1.10 linker histone 2.5617
CTIF CBP80/20-dependent translation initiation factor 2.5587
IFT57 intraflagellar transport 57 2.5586
FAM13A family with sequence similarity 13, member A 2.55858
EMD emerin 2.55855
DUSP4 dual specificity phosphatase 4 2.55815
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.5576
PDE12 phosphodiesterase 12 2.5572
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5 2.55635
BANF1 barrier to autointegration factor 1 2.55615
NOL10 nucleolar protein 10 2.5552
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 2.55502
BMP5 bone morphogenetic protein 5 2.5549
G6PC2 glucose-6-phosphatase, catalytic, 2 2.55485
CNOT3 CCR4-NOT transcription complex, subunit 3 2.55352
UPK2 uroplakin 2 2.553
RECQL4 RecQ protein-like 4 2.5519
KCNIP2 Kv channel interacting protein 2 2.55095
ADIPOQ adiponectin, C1Q and collagen domain containing 2.5505
HSFX2 heat shock transcription factor family, X linked 2 2.5502
TAS2R8 taste receptor, type 2, member 8 2.5502
CDC37 cell division cycle 37 2.54995
CCNH cyclin H 2.5492
IRF2BP1 interferon regulatory factor 2 binding protein 1 2.54865
IGSF6 immunoglobulin superfamily, member 6 2.5475
ECHDC3 enoyl CoA hydratase domain containing 3 2.54685
PCDHA2 protocadherin alpha 2 2.54685
GPRIN2 G protein regulated inducer of neurite outgrowth 2 2.54675
TOP6BL TOP6B like initiator of meiotic double strand breaks 2.54505
NPTX2 neuronal pentraxin II 2.54415
CFAP298 cilia and flagella associated protein 298 2.5441
STRN4 striatin, calmodulin binding protein 4 2.5435
GMIP GEM interacting protein 2.54325
ACOXL acyl-CoA oxidase-like 2.543
MAP7 microtubule-associated protein 7 2.54297
MTMR1 myotubularin related protein 1 2.54198
NOX3 NADPH oxidase 3 2.5414
COL8A2 collagen, type VIII, alpha 2 2.54113
SUSD4 sushi domain containing 4 2.541
GRIA1 glutamate receptor, ionotropic, AMPA 1 2.54098
EFNA5 ephrin-A5 2.54098
SOCS2 suppressor of cytokine signaling 2 2.54077
RHOQ ras homolog family member Q 2.53931
TEX12 testis expressed 12 2.5392
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase 2.539
ZC3H3 zinc finger CCCH-type containing 3 2.53895
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha 2.5389
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 2.5386
MYF5 myogenic factor 5 2.53795
DIO2 deiodinase, iodothyronine, type II 2.53737
PBLD phenazine biosynthesis-like protein domain containing 2.5373
CLIC5 chloride intracellular channel 5 2.5372
H1-2 H1.2 linker histone, cluster member 2.53535
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 2.53275
ONECUT1 one cut homeobox 1 2.5317
ITGA8 integrin, alpha 8 2.5316
AXL AXL receptor tyrosine kinase 2.52895
PRSS16 protease, serine, 16 (thymus) 2.52875
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 2.52822
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 2.52735
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa 2.5272
CHD9NB CHD9 neighbor 2.52695
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 2.52673
ULBP1 UL16 binding protein 1 2.52605
PTH1R parathyroid hormone 1 receptor 2.52555
AP3S1 adaptor-related protein complex 3, sigma 1 subunit 2.5246
CLCN4 chloride channel, voltage-sensitive 4 2.52354
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 2.52285
NSDHL NAD(P) dependent steroid dehydrogenase-like 2.52277
ULK2 unc-51 like autophagy activating kinase 2 2.52215
INSRR insulin receptor-related receptor 2.5217
NEUROG2 neurogenin 2 2.5201
TTC21B tetratricopeptide repeat domain 21B 2.52005
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 2.51982
GSTA3 glutathione S-transferase alpha 3 2.519
TSPO translocator protein (18kDa) 2.5188
NLGN3 neuroligin 3 2.5179
UBE2M ubiquitin-conjugating enzyme E2M 2.51675
ZNF749 zinc finger protein 749 2.51375
ALOXE3 arachidonate lipoxygenase 3 2.51195
HRH4 histamine receptor H4 2.51035
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 2.51
CFAP43 cilia and flagella associated protein 43 2.5098
SLC7A10 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 2.5098
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 2.50975
ESR2 estrogen receptor 2 (ER beta) 2.50826
NPY2R neuropeptide Y receptor Y2 2.50675
OR5I1 olfactory receptor, family 5, subfamily I, member 1 2.5066
CMKLR1 chemerin chemokine-like receptor 1 2.50457
EPB41L1 erythrocyte membrane protein band 4.1-like 1 2.50392
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa 2.50253
LAGE3 L antigen family, member 3 2.5017
DENND1A DENN/MADD domain containing 1A 2.50135
LITAF lipopolysaccharide-induced TNF factor 2.50135
CEP70 centrosomal protein 70kDa 2.5011
NAXD NAD(P)HX dehydratase 2.49965
ATP1B4 ATPase, Na+/K+ transporting, beta 4 polypeptide 2.4992
MUC2 mucin 2, oligomeric mucus/gel-forming 2.4989
ATP13A1 ATPase type 13A1 2.49765
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 2.49525
TRPC4 transient receptor potential cation channel, subfamily C, member 4 2.4927
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa 2.49085
WFDC1 WAP four-disulfide core domain 1 2.48895
DRC3 dynein regulatory complex subunit 3 2.48865
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 2.48782
SACK1E scaffolding CK1 anchoring protein E 2.4872
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 2.48703
TRO trophinin 2.48672
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 2.48655
PDE10A phosphodiesterase 10A 2.48612
GLT8D2 glycosyltransferase 8 domain containing 2 2.4858
ARF3 ADP-ribosylation factor 3 2.48563
CYB561 cytochrome b561 2.48494
RITA1 RBPJ interacting and tubulin associated 1 2.48467
KANSL1L KAT8 regulatory NSL complex subunit 1-like 2.48395
LMAN1L lectin, mannose-binding, 1 like 2.4834
IFNA8 interferon, alpha 8 2.4833
PHF14 PHD finger protein 14 2.48315
ALPL alkaline phosphatase, liver/bone/kidney 2.48285
KDR kinase insert domain receptor 2.48285
ACKR5 atypical chemokine receptor 5 2.4823
PDAP1 PDGFA associated protein 1 2.48205
PCDHA9 protocadherin alpha 9 2.48085
TLX1 T-cell leukemia homeobox 1 2.4801
TLX2 T-cell leukemia homeobox 2 2.48002
MID2 midline 2 2.4799
ZNF440 zinc finger protein 440 2.4799
APOOL apolipoprotein O-like 2.47967
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 2.47915
IFNA13 interferon, alpha 13 2.47845
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 2.47835
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic 2.47795
BTK Bruton agammaglobulinemia tyrosine kinase 2.4756
CRMP1 collapsin response mediator protein 1 2.47465
WWC2 WW and C2 domain containing 2 2.4741
EMILIN1 elastin microfibril interfacer 1 2.47325
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 2.47315
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 2.47285
NUAK2 NUAK family, SNF1-like kinase, 2 2.4719
HTATSF1 HIV-1 Tat specific factor 1 2.47167
ASIC1 acid sensing (proton gated) ion channel 1 2.47092
DAD1 defender against cell death 1 2.47005
CORT cortistatin 2.46815
PCDHB6 protocadherin beta 6 2.4675
RNF186 ring finger protein 186 2.4674
DGKB diacylglycerol kinase, beta 90kDa 2.4647
SUSD5 sushi domain containing 5 2.4646
MED25 mediator complex subunit 25 2.46443
VGLL3 vestigial-like family member 3 2.4637
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 2.46365
IFNW1 interferon, omega 1 2.46255
COL4A6 collagen, type IV, alpha 6 2.4617
HABP2 hyaluronan binding protein 2 2.461
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 2.45987
RBM8A RNA binding motif protein 8A 2.45981
GDI1 GDP dissociation inhibitor 1 2.45975
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 2.45955
KALRN kalirin, RhoGEF kinase 2.45905
LOC107985101 uncharacterized LOC107985101 2.45825
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8 2.45765
TMEM120B transmembrane protein 120B 2.4575
MYO1B myosin IB 2.45707
FKBP4 FK506 binding protein 4, 59kDa 2.45425
ARMCX4 armadillo repeat containing, X-linked 4 2.45365
AVPR2 arginine vasopressin receptor 2 2.45298
CBLN1 cerebellin 1 precursor 2.45255
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) 2.45135
PARP8 poly (ADP-ribose) polymerase family, member 8 2.45095
RAB1B RAB1B, member RAS oncogene family 2.45075
FAM90A1 family with sequence similarity 90, member A1 2.45065
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 2.45045
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 2.4478
TBX10 T-box 10 2.44767
KIFC3 kinesin family member C3 2.4473
PFKL phosphofructokinase, liver 2.44717
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 2.4453
SPINK4 serine peptidase inhibitor, Kazal type 4 2.4451
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 2.4448
TSPAN4 tetraspanin 4 2.44458
GADD45A growth arrest and DNA-damage-inducible, alpha 2.43965
H2AJ H2A.J histone 2.43815
BOP1 block of proliferation 1 2.43695
LPA lipoprotein, Lp(a) 2.4368
RDH8 retinol dehydrogenase 8 (all-trans) 2.4367
MUC5B mucin 5B, oligomeric mucus/gel-forming 2.43647
MYL9 myosin, light chain 9, regulatory 2.43645
GUF1 GUF1 GTPase homolog (S. cerevisiae) 2.43615
HUNK hormonally up-regulated Neu-associated kinase 2.43565
FFAR3 free fatty acid receptor 3 2.43505
DLL3 delta-like 3 (Drosophila) 2.4347
GUCA1ANB-GUCA1A GUCA1ANB-GUCA1A readthrough 2.43453
PCDHGA11 protocadherin gamma subfamily A, 11 2.4327
GUCY1A2 guanylate cyclase 1, soluble, alpha 2 2.4326
RALYL RALY RNA binding protein-like 2.43245
ZSCAN26 zinc finger and SCAN domain containing 26 2.4322
EHMT2 euchromatic histone-lysine N-methyltransferase 2 2.43217
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 2.431
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12 2.431
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 2.4304
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 2.42947
PHF24 PHD finger protein 24 2.42882
ZDHHC13 zinc finger, DHHC-type containing 13 2.4264
PCDHA6 protocadherin alpha 6 2.4264
LRRC8B leucine rich repeat containing 8 family, member B 2.42565
ALDOB aldolase B, fructose-bisphosphate 2.42561
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.4251
EPB41L3 erythrocyte membrane protein band 4.1-like 3 2.425
BTG3 BTG family, member 3 2.42487
HIF3A hypoxia inducible factor 3, alpha subunit 2.42367
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like 2.42325
S100A5 S100 calcium binding protein A5 2.42315
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.42075
ARHGAP33 Rho GTPase activating protein 33 2.42015
RAB31 RAB31, member RAS oncogene family 2.42013
PLXNA2 plexin A2 2.4197
ZNF248 zinc finger protein 248 2.419
FBXW10B F-box and WD repeat domain containing 10B 2.419
PTPRU protein tyrosine phosphatase, receptor type, U 2.41865
CYSLTR2 cysteinyl leukotriene receptor 2 2.41725
ROGDI rogdi homolog (Drosophila) 2.41685
SARM1 sterile alpha and TIR motif containing 1 2.4167
CEP41 centrosomal protein 41kDa 2.4148
ATP10B ATPase, class V, type 10B 2.41393
HOXD9 homeobox D9 2.4124
RUFY1 RUN and FYVE domain containing 1 2.41235
ZFP69B ZFP69 zinc finger protein B 2.4121
SLC30A3 solute carrier family 30 (zinc transporter), member 3 2.41175
CALCR calcitonin receptor 2.4099
CD320 CD320 molecule 2.40965
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 2.40855
BRS3 bombesin-like receptor 3 2.40725
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 2.40615
FCHO1 FCH domain only 1 2.4056
LRRN2 leucine rich repeat neuronal 2 2.40515
PRIM2 primase, DNA, polypeptide 2 (58kDa) 2.39987
ACOT7 acyl-CoA thioesterase 7 2.39978
DUOX2 dual oxidase 2 2.39865
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 2.3981
BBS9 Bardet-Biedl syndrome 9 2.39794
BICDL1 BICD family like cargo adaptor 1 2.3955
CXCR6 chemokine (C-X-C motif) receptor 6 2.39528
VSX1 visual system homeobox 1 2.3952
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 2.39495
PPP5C protein phosphatase 5, catalytic subunit 2.3945
BLNK B-cell linker 2.3929
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 2.39287
EVL Enah/Vasp-like 2.3925
MAPKAP1 mitogen-activated protein kinase associated protein 1 2.39185
APOBR apolipoprotein B receptor 2.3916
E2F1 E2F transcription factor 1 2.3912
RTN4 reticulon 4 2.39112
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 2.39075
CABP5 calcium binding protein 5 2.3905
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 2.38975
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) 2.38895
RUSC2 RUN and SH3 domain containing 2 2.38885
DGKA diacylglycerol kinase, alpha 80kDa 2.38718
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 2.3866
TCEANC2 transcription elongation factor A (SII) N-terminal and central domain containing 2 2.38635
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 2.38595
EML2 echinoderm microtubule associated protein like 2 2.3859
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 2.38425
PBX3 pre-B-cell leukemia homeobox 3 2.3823
TPM2 tropomyosin 2 (beta) 2.38223
SPRYD7 SPRY domain containing 7 2.38185
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.38157
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa 2.3811
TUBGCP2 tubulin, gamma complex associated protein 2 2.3807
HIP1R huntingtin interacting protein 1 related 2.38045
PPP1R17 protein phosphatase 1, regulatory subunit 17 2.3801
TMEM214 transmembrane protein 214 2.38005
KLK13 kallikrein-related peptidase 13 2.37948
KIAA0319 KIAA0319 2.3781
VEGFB vascular endothelial growth factor B 2.37795
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B 2.3775
ZNF235 zinc finger protein 235 2.3773
CFAP69 cilia and flagella associated protein 69 2.37715
CNKSR1 connector enhancer of kinase suppressor of Ras 1 2.3769
ZNF81 zinc finger protein 81 2.37655
KDM4C lysine (K)-specific demethylase 4C 2.37628
GJD3 gap junction protein, delta 3, 31.9kDa 2.3753
ADAM18 ADAM metallopeptidase domain 18 2.3732
ALDH1B1 aldehyde dehydrogenase 1 family, member B1 2.3731
KCTD5 potassium channel tetramerization domain containing 5 2.37255

decreased expression

Symbol Name Standardized Value
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -10.0
IER3 immediate early response 3 -10.0
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -10.0
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -10.0
MYC v-myc avian myelocytomatosis viral oncogene homolog -10.0
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -9.5899
KHDC4 KH domain containing 4, pre-mRNA splicing factor -9.4709
CDK7 cyclin-dependent kinase 7 -9.4415
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -9.39365
DDIT4 DNA-damage-inducible transcript 4 -9.13645
ZW10 zw10 kinetochore protein -8.9518
TRIB1 tribbles pseudokinase 1 -8.7264
NCK1 NCK adaptor protein 1 -8.42537
PCNA proliferating cell nuclear antigen -8.0862
TXLNA taxilin alpha -7.96355
CCNB2 cyclin B2 -7.92055
DUSP6 dual specificity phosphatase 6 -7.66095
KEAP1 kelch-like ECH-associated protein 1 -7.5326
FASTKD5 FAST kinase domains 5 -7.49355
MELK maternal embryonic leucine zipper kinase -7.48345
TWF2 twinfilin actin binding protein 2 -7.3873
RFC2 replication factor C (activator 1) 2, 40kDa -7.25772
RPP38 ribonuclease P/MRP 38kDa subunit -7.20005
CASP3 caspase 3, apoptosis-related cysteine peptidase -7.1585
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -6.5663
HEATR1 HEAT repeat containing 1 -6.4137
KLHL21 kelch-like family member 21 -6.3997
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -6.35843
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -6.26237
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -6.2393
SPAG4 sperm associated antigen 4 -6.07325
CCNB1 cyclin B1 -6.06405
ZBTB35 zinc finger and BTB domain containing 35 -6.04583
AKAP8 A kinase (PRKA) anchor protein 8 -6.02313
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -6.0021
TXNRD1 thioredoxin reductase 1 -5.9624
TOP2A topoisomerase (DNA) II alpha 170kDa -5.8977
ZDHHC6 zinc finger, DHHC-type containing 6 -5.81105
C5 complement component 5 -5.7435
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -5.709
JMJD6 jumonji domain containing 6 -5.68087
NUP85 nucleoporin 85kDa -5.66835
RBM15B RNA binding motif protein 15B -5.4895
C2CD5 C2 calcium-dependent domain containing 5 -5.4426
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -5.41115
EAPP E2F-associated phosphoprotein -5.33315
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -5.3053
PUF60 poly-U binding splicing factor 60KDa -5.2706
TOMM70 translocase of outer mitochondrial membrane 70 -5.16975
ANKRD10 ankyrin repeat domain 10 -5.10125
HSPA1A heat shock 70kDa protein 1A -4.9878
NUP62 nucleoporin 62kDa -4.94565
DCK deoxycytidine kinase -4.899
MAT2A methionine adenosyltransferase II, alpha -4.83155
TBPL1 TBP-like 1 -4.81925
TRIB3 tribbles pseudokinase 3 -4.8129
NRIP1 nuclear receptor interacting protein 1 -4.78818
ZMIZ1 zinc finger, MIZ-type containing 1 -4.67635
CDC20 cell division cycle 20 -4.66275
RNMT RNA (guanine-7-) methyltransferase -4.65475
HOXA5 homeobox A5 -4.64045
INPP1 inositol polyphosphate-1-phosphatase -4.60285
CDK1 cyclin-dependent kinase 1 -4.58433
RGS2 regulator of G-protein signaling 2 -4.57995
GLOD4 glyoxalase domain containing 4 -4.5489
ARID4B AT rich interactive domain 4B (RBP1-like) -4.54145
PPP1R8 protein phosphatase 1, regulatory subunit 8 -4.5265
ADO 2-aminoethanethiol (cysteamine) dioxygenase -4.51225
EGR1 early growth response 1 -4.498
VAT1 vesicle amine transport 1 -4.4614
TATDN2 TatD DNase domain containing 2 -4.43075
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -4.36968
SNUPN snurportin 1 -4.33785
THAP11 THAP domain containing 11 -4.2299
FAT1 FAT atypical cadherin 1 -4.2198
CCNA2 cyclin A2 -4.17597
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -4.16955
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -4.10595
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -4.1013
BCL10 B-cell CLL/lymphoma 10 -4.0595
VGLL4 vestigial-like family member 4 -3.9795
ATMIN ATM interactor -3.93923
SMG8 SMG8 nonsense mediated mRNA decay factor -3.93525
ZBTB11 zinc finger and BTB domain containing 11 -3.8822
ZCCHC8 zinc finger, CCHC domain containing 8 -3.84665
KDM3A lysine (K)-specific demethylase 3A -3.8399
INTS3 integrator complex subunit 3 -3.8361
SUZ12 SUZ12 polycomb repressive complex 2 subunit -3.83547
SPPL2A signal peptide peptidase like 2A -3.8139
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.80607
CYTH1 cytohesin 1 -3.7924
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -3.778
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.7419
TUBB6 tubulin, beta 6 class V -3.7232
PELO pelota homolog (Drosophila) -3.65855
NPTN neuroplastin -3.63705
SYNGAP1 synaptic Ras GTPase activating protein 1 -3.61503
RNASE7 ribonuclease, RNase A family, 7 -3.60422
GOLT1B golgi transport 1B -3.5884
TMEM186 transmembrane protein 186 -3.5701
LBR lamin B receptor -3.56535
ZNF443 zinc finger protein 443 -3.56055
WDR82 WD repeat domain 82 -3.48525
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -3.46277
MRPL46 mitochondrial ribosomal protein L46 -3.45965
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -3.4579
ZNF263 zinc finger protein 263 -3.4456
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -3.4261
GGNBP2 gametogenetin binding protein 2 -3.41405
B4GAT1 beta-1,4-glucuronyltransferase 1 -3.41165
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -3.3917
NFE2L2 nuclear factor, erythroid 2-like 2 -3.3852
GOLPH3 golgi phosphoprotein 3 (coat-protein) -3.38215
WDR37 WD repeat domain 37 -3.3764
TCERG1 transcription elongation regulator 1 -3.3757
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -3.33905
ZZZ3 zinc finger, ZZ-type containing 3 -3.29335
SETD5 SET domain containing 5 -3.28895
COPB1 coatomer protein complex, subunit beta 1 -3.27857
PRPF4 pre-mRNA processing factor 4 -3.2664
MUL1 mitochondrial E3 ubiquitin protein ligase 1 -3.25455
BMP4 bone morphogenetic protein 4 -3.2394
CEP76 centrosomal protein 76kDa -3.22945
NRBF2 nuclear receptor binding factor 2 -3.20825
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -3.1933
IST1 increased sodium tolerance 1 homolog (yeast) -3.19255
ZNF518A zinc finger protein 518A -3.1758
TENT5A terminal nucleotidyltransferase 5A -3.1755
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) -3.15505
PRPF38B pre-mRNA processing factor 38B -3.15007
GOLPH3L golgi phosphoprotein 3-like -3.14065
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -3.1323
PSRC1 proline/serine-rich coiled-coil 1 -3.1311
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -3.1271
GABPB1 GA binding protein transcription factor, beta subunit 1 -3.10917
RNF111 ring finger protein 111 -3.0928
TASOR2 transcription activation suppressor family member 2 -3.08735
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) -3.08255
MFAP1 microfibrillar-associated protein 1 -3.0803
LTF lactotransferrin -3.0791
LRP10 low density lipoprotein receptor-related protein 10 -3.0683
CASC3 cancer susceptibility candidate 3 -3.06815
FZD7 frizzled class receptor 7 -3.0672
FBXO34 F-box protein 34 -3.0667
FOSL1 FOS-like antigen 1 -3.0634
ARGLU1 arginine and glutamate rich 1 -3.05345
OTUD3 OTU deubiquitinase 3 -3.0331
CD58 CD58 molecule -3.02338
AARS1 alanyl-tRNA synthetase 1 -3.00625
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -3.00325
SCAF8 SR-related CTD-associated factor 8 -2.9991
ZC3H11B zinc finger CCCH-type containing 11B pseudogene -2.99738
RBM7 RNA binding motif protein 7 -2.9859
DENND4B DENN/MADD domain containing 4B -2.9596
SLC25A44 solute carrier family 25, member 44 -2.95948
CHSY1 chondroitin sulfate synthase 1 -2.9436
SIRAL2 SIR2 antiphage like 2 -2.93895
CREB1 cAMP responsive element binding protein 1 -2.93349
HMGXB4 HMG box domain containing 4 -2.9278
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -2.91575
TEFM transcription elongation factor, mitochondrial -2.91185
SMNDC1 survival motor neuron domain containing 1 -2.90585
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -2.90225
CRK v-crk avian sarcoma virus CT10 oncogene homolog -2.88805
GPC3 glypican 3 -2.88155
CRBN cereblon -2.8735
KMT5B lysine methyltransferase 5B -2.8496
CLTC clathrin, heavy chain (Hc) -2.8475
BFAR bifunctional apoptosis regulator -2.8435
SUCO SUN domain containing ossification factor -2.8377
HOMER1 homer scaffolding protein 1 -2.8299
RPL36AL ribosomal protein L36a-like -2.8259
MACF1 microtubule-actin crosslinking factor 1 -2.82459
PUM2 pumilio RNA-binding family member 2 -2.8233
NEK7 NIMA-related kinase 7 -2.8173
TM9SF3 transmembrane 9 superfamily member 3 -2.81465
EMC8 ER membrane protein complex subunit 8 -2.80815
THUMPD1 THUMP domain containing 1 -2.8024
KAT6A K(lysine) acetyltransferase 6A -2.79583
MAK16 MAK16 homolog (S. cerevisiae) -2.78765
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -2.7817
CTSH cathepsin H -2.7763
FNBP4 formin binding protein 4 -2.76775
SIAH2 siah E3 ubiquitin protein ligase 2 -2.76435
PUM1 pumilio RNA-binding family member 1 -2.7638
TTC4 tetratricopeptide repeat domain 4 -2.7596
RBM6 RNA binding motif protein 6 -2.74685
PEX12 peroxisomal biogenesis factor 12 -2.7451
NOL11 nucleolar protein 11 -2.7355
SEC24B SEC24 family member B -2.71625
SPOP speckle-type POZ protein -2.71242
DKK1 dickkopf WNT signaling pathway inhibitor 1 -2.70105
LASP1 LIM and SH3 protein 1 -2.679
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 -2.6718
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -2.66728
SRSF2 serine/arginine-rich splicing factor 2 -2.66722
IER2 immediate early response 2 -2.66395
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -2.6604
ZNF267 zinc finger protein 267 -2.65535
CDKN2A cyclin-dependent kinase inhibitor 2A -2.64497
LIF leukemia inhibitory factor -2.64325
RBM15 RNA binding motif protein 15 -2.64113
KIF14 kinesin family member 14 -2.6361
LARP4 La ribonucleoprotein domain family, member 4 -2.62715
AK6 adenylate kinase 6 -2.623
NMI N-myc (and STAT) interactor -2.61915
DNM1L dynamin 1-like -2.61535
TMEM97 transmembrane protein 97 -2.61388
AHSG alpha-2-HS-glycoprotein -2.61062
SDF2 stromal cell-derived factor 2 -2.58575
IER5 immediate early response 5 -2.58205
PMPCA peptidase (mitochondrial processing) alpha -2.5791
SLC38A2 solute carrier family 38, member 2 -2.5785
CTR9 CTR9, Paf1/RNA polymerase II complex component -2.5756
RESF1 retroelement silencing factor 1 -2.5736
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -2.5678
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -2.55605
IL4R interleukin 4 receptor -2.5532
NCOA3 nuclear receptor coactivator 3 -2.55282
SACS sacsin molecular chaperone -2.54795
BAG3 BCL2-associated athanogene 3 -2.5476
RLF rearranged L-myc fusion -2.53935
DCPH1 damage control phosphatase 1 -2.53775
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) -2.53565
RBMX2 RNA binding motif protein, X-linked 2 -2.53482
QTRT2 queuine tRNA-ribosyltransferase accessory subunit 2 -2.53155
AFG3L2 AFG3-like AAA ATPase 2 -2.52195
TCTN1 tectonic family member 1 -2.50785
WDR43 WD repeat domain 43 -2.5024
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 -2.5012
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.4942
MRM3 mitochondrial rRNA methyltransferase 3 -2.49305
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 -2.4797
MSH6 mutS homolog 6 -2.47825
FBXO5 F-box protein 5 -2.47515
RPL29 ribosomal protein L29 -2.46788
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.4672
CEMIP2 cell migration inducing hyaluronidase 2 -2.46605
IQGAP2 IQ motif containing GTPase activating protein 2 -2.46015
LCMT2 leucine carboxyl methyltransferase 2 -2.45955
UCK2 uridine-cytidine kinase 2 -2.45665
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -2.45445
PPID peptidylprolyl isomerase D -2.44553
SASH3 SAM and SH3 domain containing 3 -2.4437
IGHMBP2 immunoglobulin mu binding protein 2 -2.43718
PRRC1 proline-rich coiled-coil 1 -2.43235
MGA MGA, MAX dimerization protein -2.4317
YY1AP1 YY1 associated protein 1 -2.4213
RSRP1 arginine/serine-rich protein 1 -2.41027
ASCC3 activating signal cointegrator 1 complex subunit 3 -2.40525
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -2.40305
BATF3 basic leucine zipper transcription factor, ATF-like 3 -2.3985
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.39742
NENF neudesin neurotrophic factor -2.3905
MIS12 MIS12 kinetochore complex component -2.38755
FEM1B fem-1 homolog b (C. elegans) -2.3865
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.38645
TTI2 TELO2 interacting protein 2 -2.3823
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -2.3816
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -2.3813
PLK2 polo-like kinase 2 -2.38095
DUSP13A dual specificity phosphatase 13A -2.3752
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 -2.3742
ADAM10 ADAM metallopeptidase domain 10 -2.37307
BTBD3 BTB (POZ) domain containing 3 -2.36675
TBC1D3G TBC1 domain family member 3G -2.36605
CHTOP chromatin target of PRMT1 -2.36528
APOA1 apolipoprotein A-I -2.3643
SETD1B SET domain containing 1B -2.36315
RNF113A ring finger protein 113A -2.36175
APOA2 apolipoprotein A-II -2.3563
TRAPPC4 trafficking protein particle complex 4 -2.35035
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa -2.3492
RBM14-RBM4 RBM14-RBM4 readthrough -2.3491
NPY neuropeptide Y -2.34815
REEP5 receptor accessory protein 5 -2.34637
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 -2.3423
POLR1D polymerase (RNA) I polypeptide D, 16kDa -2.3422
RSBN1 round spermatid basic protein 1 -2.3419
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 -2.3282
TXNDC9 thioredoxin domain containing 9 -2.32263
OXSM 3-oxoacyl-ACP synthase, mitochondrial -2.3225
MGST2 microsomal glutathione S-transferase 2 -2.31915
RHOF ras homolog family member F (in filopodia) -2.31845
MMP7 matrix metallopeptidase 7 -2.3171
TMEM115 transmembrane protein 115 -2.31635
CEP192 centrosomal protein 192kDa -2.3154
GALK1 galactokinase 1 -2.31505
CHKA choline kinase alpha -2.31442
BCOR BCL6 corepressor -2.313
ZDHHC7 zinc finger, DHHC-type containing 7 -2.30965
GOLGA3 golgin A3 -2.3071
CNIH1 cornichon family AMPA receptor auxiliary protein 1 -2.3066
CDKN2AIP CDKN2A interacting protein -2.30605
MANF mesencephalic astrocyte-derived neurotrophic factor -2.29985
BAZ1A bromodomain adjacent to zinc finger domain, 1A -2.29732
ZNF146 zinc finger protein 146 -2.29385
PPCDC phosphopantothenoylcysteine decarboxylase -2.2937
MARCHF7 membrane associated ring-CH-type finger 7 -2.29285
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -2.28925
SKIC2 SKI2 subunit of superkiller complex -2.2874
TIPIN TIMELESS interacting protein -2.28735
S100PBP S100P binding protein -2.27885
UNC50 unc-50 homolog (C. elegans) -2.27845
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -2.2783
PNN pinin, desmosome associated protein -2.2764
QPRT quinolinate phosphoribosyltransferase -2.2714
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -2.2675
LIPT1 lipoyltransferase 1 -2.26645
ZBTB38 zinc finger and BTB domain containing 38 -2.26015
DPY19L1 dpy-19-like 1 (C. elegans) -2.255
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.25335
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 -2.2518
RIOK2 RIO kinase 2 -2.25125
MRPL17 mitochondrial ribosomal protein L17 -2.2393
DYNLL1 dynein, light chain, LC8-type 1 -2.23695
SRP54 signal recognition particle 54kDa -2.2298
PAQR6 progestin and adipoQ receptor family member VI -2.2292
RPP25 ribonuclease P/MRP 25kDa subunit -2.2279
SSUH2 ssu-2 homolog (C. elegans) -2.22715
AAR2 AAR2 splicing factor homolog (S. cerevisiae) -2.22695
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.22253
CX3CR1 chemokine (C-X3-C motif) receptor 1 -2.2191
URGCP upregulator of cell proliferation -2.2165
BTN2A1 butyrophilin, subfamily 2, member A1 -2.21617
XPO1 exportin 1 -2.20985
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing -2.2077
RBM5 RNA binding motif protein 5 -2.2061
MBIP MAP3K12 binding inhibitory protein 1 -2.2061
MLEC malectin -2.20565
SPDL1 spindle apparatus coiled-coil protein 1 -2.2048
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -2.2045
MSX1 msh homeobox 1 -2.20395
EXOSC10 exosome component 10 -2.2035
AGO2 argonaute RISC catalytic component 2 -2.20305
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) -2.20275
THAP12 THAP domain containing 12 -2.20085
E2F6 E2F transcription factor 6 -2.2007
TMEM39A transmembrane protein 39A -2.19505
GMFB glia maturation factor, beta -2.18712
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 -2.1869
TBC1D4 TBC1 domain family, member 4 -2.17947
MAD2L1BP MAD2L1 binding protein -2.1718
SEC24A SEC24 family member A -2.16587
FAM216A family with sequence similarity 216, member A -2.1645
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 -2.1641
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 -2.16375
DHRS2 dehydrogenase/reductase (SDR family) member 2 -2.1621
UGCG UDP-glucose ceramide glucosyltransferase -2.15427
BANP BTG3 associated nuclear protein -2.15305
HDAC4 histone deacetylase 4 -2.1517
MRFAP1L1 Morf4 family associated protein 1-like 1 -2.15035
NPY5R neuropeptide Y receptor Y5 -2.14925
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -2.1487
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) -2.14805
HELZ helicase with zinc finger -2.1441
NISCH nischarin -2.14335
UBE3C ubiquitin protein ligase E3C -2.14295
VCPKMT valosin containing protein lysine (K) methyltransferase -2.1391
PLA2G15 phospholipase A2, group XV -2.1371
ZNF217 zinc finger protein 217 -2.13145
RAB22A RAB22A, member RAS oncogene family -2.13002
HSPA8 heat shock 70kDa protein 8 -2.12892
NOP16 NOP16 nucleolar protein -2.12065
SEC16A SEC16 homolog A (S. cerevisiae) -2.1142
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -2.1136
CDC123 cell division cycle 123 -2.1135
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A -2.11173
GTF2H2C GTF2H2 family member C -2.11067
SPTSSA serine palmitoyltransferase, small subunit A -2.10868
DCP2 decapping mRNA 2 -2.1085
CDC25B cell division cycle 25B -2.10765
UTP11 UTP11 small subunit processome component -2.1075
FOS FBJ murine osteosarcoma viral oncogene homolog -2.10745
ARID5B AT rich interactive domain 5B (MRF1-like) -2.107
ADNP activity-dependent neuroprotector homeobox -2.10695
ANKRD17 ankyrin repeat domain 17 -2.10295
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa -2.1029
HHEX hematopoietically expressed homeobox -2.10195
VTA1 vesicle (multivesicular body) trafficking 1 -2.10075
COLGALT2 collagen beta(1-O)galactosyltransferase 2 -2.0981
TBCC tubulin folding cofactor C -2.09705
PCF11 PCF11 cleavage and polyadenylation factor subunit -2.09695
CDKN3 cyclin-dependent kinase inhibitor 3 -2.09235
MED17 mediator complex subunit 17 -2.09215
MNT MAX network transcriptional repressor -2.08775
SYNGR3 synaptogyrin 3 -2.08695
LMO2 LIM domain only 2 (rhombotin-like 1) -2.0851
TMEM185B transmembrane protein 185B -2.0748
ZNF281 zinc finger protein 281 -2.07475
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -2.07435
GRWD1 glutamate-rich WD repeat containing 1 -2.0732
CNPY3 canopy FGF signaling regulator 3 -2.06895
TMEM267 transmembrane protein 267 -2.0663
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 -2.0615
ATG101 autophagy related 101 -2.0604
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) -2.05955
PRPF3 pre-mRNA processing factor 3 -2.05825
SREK1 splicing regulatory glutamine/lysine-rich protein 1 -2.05385
REXO2 RNA exonuclease 2 -2.0528
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.0516
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -2.04795
ZNF318 zinc finger protein 318 -2.04562
MAVS mitochondrial antiviral signaling protein -2.04295
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -2.0412
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 -2.0403
TMPRSS11E transmembrane protease, serine 11E -2.0361
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 -2.0332
CCNE1 cyclin E1 -2.02695
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 -2.0182
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 -2.01568
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -2.01315
ZNF106 zinc finger protein 106 -2.01235
PPY pancreatic polypeptide -2.01227
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -2.01204
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa -2.00358
HTD2 hydroxyacyl-thioester dehydratase type 2 -2.0018
DCLRE1B DNA cross-link repair 1B -2.0006
FGL1 fibrinogen-like 1 -2.00005