CRCGN008_HEPG2_24H:D03 Gene Set
Genes
41 genes differentially expressed following the CRCGN008_HEPG2_24H:D03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
E2F2
|
E2F transcription factor 2
|
10.0
|
|
NMU
|
neuromedin U
|
5.5719
|
|
UBQLN2
|
ubiquilin 2
|
4.86525
|
|
RPL39L
|
ribosomal protein L39-like
|
4.8061
|
|
RRAGA
|
Ras-related GTP binding A
|
4.0252
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.86275
|
|
IDE
|
insulin-degrading enzyme
|
3.69663
|
|
RAB11FIP2
|
RAB11 family interacting protein 2 (class I)
|
3.60545
|
|
H2BC12
|
H2B clustered histone 12
|
3.20005
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.11255
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
3.05855
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.8153
|
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
2.52235
|
|
ARFIP2
|
ADP-ribosylation factor interacting protein 2
|
2.4232
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.34855
|
|
STXBP2
|
syntaxin binding protein 2
|
2.33115
|
|
PSIP1
|
PC4 and SFRS1 interacting protein 1
|
2.32318
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.2766
|
|
LCN2
|
lipocalin 2
|
2.2498
|
|
EVL
|
Enah/Vasp-like
|
2.22285
|
|
MMAB
|
methylmalonic aciduria (cobalamin deficiency) cblB type
|
2.209
|
|
EPHA3
|
EPH receptor A3
|
2.16973
|
|
LRRC47
|
leucine rich repeat containing 47
|
2.15225
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
2.03592
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.00893
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC35F2
|
solute carrier family 35, member F2
|
-8.68025
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.95075
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.9253
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.83225
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.81465
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.7417
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-4.72095
|
|
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1
|
-4.08065
|
|
CSNK1E
|
casein kinase 1, epsilon
|
-3.04642
|
|
RNF167
|
ring finger protein 167
|
-3.01985
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.6159
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.6036
|
|
PARM1
|
prostate androgen-regulated mucin-like protein 1
|
-2.196
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.14035
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.1237
|
|
C1GALT1C1
|
C1GALT1-specific chaperone 1
|
-2.0666
|
