| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tetrakis(hydroxymethyl)phosphonium sulfate 1.26 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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84 genes differentially expressed following the CRCGN008_HEPG2_24H:D06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBQLN2 | ubiquilin 2 | 10.0 |
| LCN2 | lipocalin 2 | 6.44685 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 5.1701 |
| CCDC92 | coiled-coil domain containing 92 | 4.9542 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.91745 |
| CBR3 | carbonyl reductase 3 | 4.6311 |
| CHMP6 | charged multivesicular body protein 6 | 4.58845 |
| EPHA3 | EPH receptor A3 | 4.4606 |
| LOC122526780 | uncharacterized LOC122526780 | 4.45185 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 4.17637 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 4.073 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.59155 |
| EPN2 | epsin 2 | 3.52853 |
| ZNF589 | zinc finger protein 589 | 3.45403 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.39755 |
| EVL | Enah/Vasp-like | 3.3833 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 3.23588 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.89507 |
| FPGS | folylpolyglutamate synthase | 2.8814 |
| NMU | neuromedin U | 2.74325 |
| MAP7 | microtubule-associated protein 7 | 2.71317 |
| CHEK2 | checkpoint kinase 2 | 2.6869 |
| CCNF | cyclin F | 2.59628 |
| TRIM36 | tripartite motif containing 36 | 2.5431 |
| HOMER1 | homer scaffolding protein 1 | 2.52945 |
| USP6NL | USP6 N-terminal like | 2.4518 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.4504 |
| COMMD3 | COMM domain containing 3 | 2.4175 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 2.3844 |
| PRDX4 | peroxiredoxin 4 | 2.3827 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.38258 |
| RFK | riboflavin kinase | 2.35418 |
| H2BC12 | H2B clustered histone 12 | 2.33622 |
| CYCS | cytochrome c, somatic | 2.26165 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.2437 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) | 2.1912 |
| SLC6A1 | solute carrier family 6 (neurotransmitter transporter), member 1 | 2.18645 |
| CNN1 | calponin 1, basic, smooth muscle | 2.1684 |
| SPIN2B | spindlin family, member 2B | 2.1621 |
| RTN3 | reticulon 3 | 2.15015 |
| TBPL1 | TBP-like 1 | 2.1484 |
| PCYOX1 | prenylcysteine oxidase 1 | 2.08255 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | 2.01608 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.0054 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -6.5594 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -5.3068 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -5.1905 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -5.1554 |
| PCNA | proliferating cell nuclear antigen | -5.0 |
| CDC20 | cell division cycle 20 | -4.6933 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -4.67305 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -4.52435 |
| HEATR1 | HEAT repeat containing 1 | -3.77887 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | -3.74542 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.5415 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.40505 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.19115 |
| SCAND1 | SCAN domain containing 1 | -2.8727 |
| CD79B | CD79b molecule, immunoglobulin-associated beta | -2.6425 |
| SNX11 | sorting nexin 11 | -2.60675 |
| CD19 | CD19 molecule | -2.5898 |
| E4F1 | E4F transcription factor 1 | -2.46205 |
| ROPN1B | rhophilin associated tail protein 1B | -2.3952 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -2.371 |
| POMT2 | protein-O-mannosyltransferase 2 | -2.34675 |
| PDHX | pyruvate dehydrogenase complex, component X | -2.28058 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) | -2.27565 |
| SLC6A15 | solute carrier family 6 (neutral amino acid transporter), member 15 | -2.23365 |
| LMO1 | LIM domain only 1 (rhombotin 1) | -2.2139 |
| CD72 | CD72 molecule | -2.1828 |
| FKBPL | FK506 binding protein like | -2.17425 |
| PSG7 | pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) | -2.16685 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 | -2.1646 |
| ALX1 | ALX homeobox 1 | -2.15235 |
| RAB13 | RAB13, member RAS oncogene family | -2.1483 |
| FAM50B | family with sequence similarity 50, member B | -2.12 |
| TOPBP1 | topoisomerase (DNA) II binding protein 1 | -2.0761 |
| P3H1 | prolyl 3-hydroxylase 1 | -2.0631 |
| PFKM | phosphofructokinase, muscle | -2.06005 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | -2.06 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 | -2.04395 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | -2.03745 |
| CYP11A1 | cytochrome P450, family 11, subfamily A, polypeptide 1 | -2.03025 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -2.0262 |
