| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2-ethyl-2-hexenal 4.95 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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64 genes differentially expressed following the CRCGN008_HEPG2_24H:D10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBQLN2 | ubiquilin 2 | 5.19635 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.15475 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.66275 |
| STK10 | serine/threonine kinase 10 | 4.4714 |
| ABHD6 | abhydrolase domain containing 6 | 4.35443 |
| PRR15L | proline rich 15-like | 3.905 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.60665 |
| EGF | epidermal growth factor | 3.5861 |
| VGLL4 | vestigial-like family member 4 | 3.13962 |
| HEBP1 | heme binding protein 1 | 3.07925 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 3.0279 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.99148 |
| MAP7 | microtubule-associated protein 7 | 2.891 |
| CHEK2 | checkpoint kinase 2 | 2.86888 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.5012 |
| TNIP1 | TNFAIP3 interacting protein 1 | 2.4854 |
| TBP | TATA box binding protein | 2.42145 |
| RELN | reelin | 2.4021 |
| STXBP2 | syntaxin binding protein 2 | 2.3651 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.34577 |
| CEP57 | centrosomal protein 57kDa | 2.28652 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.27998 |
| GATA2 | GATA binding protein 2 | 2.25598 |
| USP6NL | USP6 N-terminal like | 2.24795 |
| NPC1L1 | NPC1-like 1 | 2.2385 |
| RBL2 | retinoblastoma-like 2 | 2.23128 |
| CD33 | CD33 molecule | 2.18735 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 2.18695 |
| KLHL9 | kelch-like family member 9 | 2.18112 |
| SHB | Src homology 2 domain containing adaptor protein B | 2.17162 |
| TEC | tec protein tyrosine kinase | 2.07635 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 | 2.0637 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.06183 |
| CDCA4 | cell division cycle associated 4 | 2.03455 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -7.81525 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -6.07385 |
| NCK1 | NCK adaptor protein 1 | -5.4031 |
| WASHC4 | WASH complex subunit 4 | -5.14303 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -5.128 |
| LDHD | lactate dehydrogenase D | -4.96705 |
| VAT1 | vesicle amine transport 1 | -4.9402 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.75375 |
| ZNF586 | zinc finger protein 586 | -4.7017 |
| TCERG1 | transcription elongation regulator 1 | -4.6031 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.85815 |
| CCNB2 | cyclin B2 | -3.7932 |
| CAB39 | calcium binding protein 39 | -3.03825 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -3.0252 |
| CCNB1 | cyclin B1 | -2.9929 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.84662 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.72625 |
| CLCA4 | chloride channel accessory 4 | -2.6734 |
| TLR3 | toll-like receptor 3 | -2.66435 |
| EXT1 | exostosin glycosyltransferase 1 | -2.39705 |
| CCP110 | centriolar coiled coil protein 110kDa | -2.3491 |
| FER | fer (fps/fes related) tyrosine kinase | -2.34315 |
| RBM34 | RNA binding motif protein 34 | -2.26925 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | -2.26333 |
| PDLIM1 | PDZ and LIM domain 1 | -2.2479 |
| BMP4 | bone morphogenetic protein 4 | -2.2091 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -2.1765 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.17078 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -2.1703 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent | -2.1637 |
