CRCGN008_HEPG2_24H:D14 Gene Set
Genes
56 genes differentially expressed following the CRCGN008_HEPG2_24H:D14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
VGLL4
|
vestigial-like family member 4
|
7.03632
|
|
PIH1D1
|
PIH1 domain containing 1
|
5.20155
|
|
ARL4C
|
ADP-ribosylation factor-like 4C
|
4.88925
|
|
NMU
|
neuromedin U
|
4.66275
|
|
MOK
|
MOK protein kinase
|
4.65645
|
|
MYLK
|
myosin light chain kinase
|
4.56035
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
4.33845
|
|
CBR3
|
carbonyl reductase 3
|
4.31015
|
|
PIP4K2B
|
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
|
3.74032
|
|
TBPL1
|
TBP-like 1
|
3.4949
|
|
CHN1
|
chimerin 1
|
3.4553
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.34958
|
|
PSMB3
|
proteasome (prosome, macropain) subunit, beta type, 3
|
2.82035
|
|
CRTAP
|
cartilage associated protein
|
2.81585
|
|
KIF5C
|
kinesin family member 5C
|
2.78268
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.73175
|
|
ECD
|
ecdysoneless homolog (Drosophila)
|
2.7048
|
|
CWC25
|
CWC25 spliceosome-associated protein homolog (S. cerevisiae)
|
2.5109
|
|
KLHL9
|
kelch-like family member 9
|
2.4548
|
|
POLR2K
|
polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
|
2.38888
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.2037
|
|
NAE1
|
NEDD8 activating enzyme E1 subunit 1
|
2.1982
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
2.1961
|
|
DNAJA2
|
DnaJ (Hsp40) homolog, subfamily A, member 2
|
2.146
|
|
UFD1
|
ubiquitin recognition factor in ER associated degradation 1
|
2.10625
|
|
PCGF2
|
polycomb group ring finger 2
|
2.07226
|
|
IRF2BP1
|
interferon regulatory factor 2 binding protein 1
|
2.0674
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
2.0395
|
|
TCF20
|
transcription factor 20 (AR1)
|
2.02295
|
|
FASTK
|
Fas-activated serine/threonine kinase
|
2.02113
|
|
HMG20A
|
high mobility group 20A
|
2.0106
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-9.21395
|
|
DNM1L
|
dynamin 1-like
|
-5.22515
|
|
TIMM9
|
translocase of inner mitochondrial membrane 9 homolog (yeast)
|
-5.0
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.0
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.75985
|
|
NUP85
|
nucleoporin 85kDa
|
-4.7592
|
|
ZNF586
|
zinc finger protein 586
|
-4.58185
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-4.20398
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.87865
|
|
HEATR1
|
HEAT repeat containing 1
|
-3.8013
|
|
GNAS
|
GNAS complex locus
|
-3.73569
|
|
TES
|
testin LIM domain protein
|
-3.20362
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.54265
|
|
ACOX1
|
acyl-CoA oxidase 1, palmitoyl
|
-2.28592
|
|
HSD17B1
|
hydroxysteroid (17-beta) dehydrogenase 1
|
-2.25955
|
|
ATF5
|
activating transcription factor 5
|
-2.23742
|
|
MRPL58
|
mitochondrial ribosomal protein L58
|
-2.13755
|
|
CDK3
|
cyclin-dependent kinase 3
|
-2.1369
|
|
MAP2K1
|
mitogen-activated protein kinase kinase 1
|
-2.1097
|
|
FAU
|
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
|
-2.10355
|
|
ZNF671
|
zinc finger protein 671
|
-2.07075
|
|
SLC7A9
|
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
|
-2.05665
|
|
PLCL1
|
phospholipase C-like 1
|
-2.0402
|
|
PLBD1
|
phospholipase B domain containing 1
|
-2.03995
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.00635
|
