CRCGN008_HEPG2_24H:D16 Gene Set
Genes
40 genes differentially expressed following the CRCGN008_HEPG2_24H:D16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PRR15L
|
proline rich 15-like
|
7.47
|
|
E2F2
|
E2F transcription factor 2
|
5.1389
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.8057
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.7154
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.66275
|
|
MAMLD1
|
mastermind-like domain containing 1
|
4.339
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
4.0166
|
|
HEBP1
|
heme binding protein 1
|
3.6117
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
3.09032
|
|
CCNF
|
cyclin F
|
2.92357
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
2.84445
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.79542
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
2.4525
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.43188
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.23375
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.13675
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
2.12855
|
|
DDX10
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
|
2.0624
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
2.0444
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-7.8115
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-5.40532
|
|
VAT1
|
vesicle amine transport 1
|
-5.1291
|
|
LDHD
|
lactate dehydrogenase D
|
-4.57485
|
|
PSMD2
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
|
-3.68785
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-3.0514
|
|
SCAND1
|
SCAN domain containing 1
|
-2.9351
|
|
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1
|
-2.9184
|
|
CDC25B
|
cell division cycle 25B
|
-2.8032
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.71643
|
|
ZNF304
|
zinc finger protein 304
|
-2.5666
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.44745
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.345
|
|
ZNF551
|
zinc finger protein 551
|
-2.2094
|
|
BMP4
|
bone morphogenetic protein 4
|
-2.15225
|
|
ZNF587B
|
zinc finger protein 587B
|
-2.091
|
|
NLRP4
|
NLR family, pyrin domain containing 4
|
-2.07055
|
|
AP2M1
|
adaptor-related protein complex 2, mu 1 subunit
|
-2.02005
|
|
ZNF813
|
zinc finger protein 813
|
-2.01725
|
|
ZNF134
|
zinc finger protein 134
|
-2.0153
|
|
ZNF84
|
zinc finger protein 84
|
-2.00055
|