CRCGN008_HEPG2_24H:D19 Gene Set
Genes
41 genes differentially expressed following the CRCGN008_HEPG2_24H:D19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CYCS
|
cytochrome c, somatic
|
6.1221
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
5.3051
|
|
HEBP1
|
heme binding protein 1
|
5.24915
|
|
CBR3
|
carbonyl reductase 3
|
4.74435
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
4.2397
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.94567
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.75245
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.59167
|
|
CDCA4
|
cell division cycle associated 4
|
3.3663
|
|
CHN1
|
chimerin 1
|
3.2036
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
3.12898
|
|
JADE2
|
jade family PHD finger 2
|
3.0283
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.02577
|
|
EGF
|
epidermal growth factor
|
2.95595
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.86942
|
|
ZNF589
|
zinc finger protein 589
|
2.64685
|
|
RAB21
|
RAB21, member RAS oncogene family
|
2.59835
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.44068
|
|
SFTPB
|
surfactant protein B
|
2.2393
|
|
APBB2
|
amyloid beta (A4) precursor protein-binding, family B, member 2
|
2.18835
|
|
FBXO46
|
F-box protein 46
|
2.139
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
2.0685
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.04895
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DSG2
|
desmoglein 2
|
-5.2377
|
|
LDHD
|
lactate dehydrogenase D
|
-5.0547
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.72685
|
|
VAT1
|
vesicle amine transport 1
|
-4.1272
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.0924
|
|
CCNB2
|
cyclin B2
|
-3.52615
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.3243
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.2414
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.66552
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.5794
|
|
CDC25B
|
cell division cycle 25B
|
-2.48995
|
|
MAP2K5
|
mitogen-activated protein kinase kinase 5
|
-2.39223
|
|
CHIC2
|
cysteine-rich hydrophobic domain 2
|
-2.36165
|
|
WASHC4
|
WASH complex subunit 4
|
-2.35505
|
|
RBM34
|
RNA binding motif protein 34
|
-2.21567
|
|
VPS33B
|
vacuolar protein sorting 33 homolog B (yeast)
|
-2.0707
|
|
GLOD4
|
glyoxalase domain containing 4
|
-2.07055
|
|
KRT7
|
keratin 7, type II
|
-2.05675
|
