CRCGN008_HEPG2_24H:D20 Gene Set
Genes
61 genes differentially expressed following the CRCGN008_HEPG2_24H:D20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
RAB21
|
RAB21, member RAS oncogene family
|
6.30995
|
|
PMM2
|
phosphomannomutase 2
|
5.86345
|
|
LAGE3
|
L antigen family, member 3
|
5.5794
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
5.4969
|
|
JADE2
|
jade family PHD finger 2
|
5.47235
|
|
CBR3
|
carbonyl reductase 3
|
5.3403
|
|
TAC4
|
tachykinin 4 (hemokinin)
|
5.0
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
4.76
|
|
MYLK
|
myosin light chain kinase
|
4.72205
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.59855
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
4.5263
|
|
EPN2
|
epsin 2
|
4.07155
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
4.0533
|
|
STIMATE
|
STIM activating enhancer
|
3.7008
|
|
CHN1
|
chimerin 1
|
3.31225
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.91715
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.90223
|
|
CCNF
|
cyclin F
|
2.7685
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.64715
|
|
CDK19
|
cyclin-dependent kinase 19
|
2.61047
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.43878
|
|
GPATCH8
|
G patch domain containing 8
|
2.33272
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.2665
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
2.24915
|
|
NLRP2B
|
NLR family pyrin domain containing 2B
|
2.24265
|
|
ECD
|
ecdysoneless homolog (Drosophila)
|
2.18065
|
|
FAM174C
|
family with sequence similarity 174 member C
|
2.15845
|
|
ZNF589
|
zinc finger protein 589
|
2.1561
|
|
HAT1
|
histone acetyltransferase 1
|
2.153
|
|
MTFR1
|
mitochondrial fission regulator 1
|
2.14477
|
|
TBP
|
TATA box binding protein
|
2.14215
|
|
CEP57
|
centrosomal protein 57kDa
|
2.09017
|
|
ACP3
|
acid phosphatase 3
|
2.08295
|
|
NMU
|
neuromedin U
|
2.04585
|
|
EPHA3
|
EPH receptor A3
|
2.03543
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
INPP1
|
inositol polyphosphate-1-phosphatase
|
-5.907
|
|
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1
|
-5.42655
|
|
USP6NL
|
USP6 N-terminal like
|
-5.2817
|
|
DSG2
|
desmoglein 2
|
-5.10445
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.8018
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.77245
|
|
CCNB2
|
cyclin B2
|
-4.6831
|
|
CCNB1
|
cyclin B1
|
-4.46165
|
|
CDC20
|
cell division cycle 20
|
-4.3123
|
|
GNAS
|
GNAS complex locus
|
-3.90679
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.6404
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-3.37623
|
|
CDC25B
|
cell division cycle 25B
|
-2.7919
|
|
ATF5
|
activating transcription factor 5
|
-2.6864
|
|
SPAG4
|
sperm associated antigen 4
|
-2.61465
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.50055
|
|
SCCPDH
|
saccharopine dehydrogenase (putative)
|
-2.4168
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.41155
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
-2.353
|
|
STXBP1
|
syntaxin binding protein 1
|
-2.27085
|
|
PIGZ
|
phosphatidylinositol glycan anchor biosynthesis, class Z
|
-2.21775
|
|
CBLN1
|
cerebellin 1 precursor
|
-2.18155
|
|
CSRNP3
|
cysteine-serine-rich nuclear protein 3
|
-2.156
|
|
MACROH2A2
|
macroH2A.2 histone
|
-2.0815
|
|
NGFR
|
nerve growth factor receptor
|
-2.00265
|
