CRCGN008_HEPG2_24H:D21 Gene Set
Genes
56 genes differentially expressed following the CRCGN008_HEPG2_24H:D21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
KIFBP
|
kinesin family binding protein
|
4.8692
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.8328
|
|
PRR15L
|
proline rich 15-like
|
4.5236
|
|
E2F2
|
E2F transcription factor 2
|
4.3563
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
4.0995
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.92467
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
3.61545
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
3.4507
|
|
HEBP1
|
heme binding protein 1
|
3.4112
|
|
DEAF1
|
DEAF1 transcription factor
|
3.32545
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.27397
|
|
ECD
|
ecdysoneless homolog (Drosophila)
|
3.02595
|
|
CTSL
|
cathepsin L
|
3.0004
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.9872
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.8063
|
|
CCNF
|
cyclin F
|
2.78327
|
|
CDK19
|
cyclin-dependent kinase 19
|
2.75142
|
|
RRAGA
|
Ras-related GTP binding A
|
2.65955
|
|
NMU
|
neuromedin U
|
2.6384
|
|
SIRT3
|
sirtuin 3
|
2.58157
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.51618
|
|
TBP
|
TATA box binding protein
|
2.4055
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.2983
|
|
MTERF3
|
mitochondrial transcription termination factor 3
|
2.26955
|
|
SFTPB
|
surfactant protein B
|
2.24227
|
|
JADE2
|
jade family PHD finger 2
|
2.2104
|
|
AXIN1
|
axin 1
|
2.20635
|
|
PIH1D1
|
PIH1 domain containing 1
|
2.1426
|
|
RIC8A
|
RIC8 guanine nucleotide exchange factor A
|
2.0503
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-6.22125
|
|
ZNF586
|
zinc finger protein 586
|
-5.21965
|
|
CCNB2
|
cyclin B2
|
-5.05
|
|
LDHD
|
lactate dehydrogenase D
|
-4.6794
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-4.06203
|
|
GNAS
|
GNAS complex locus
|
-4.03646
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-3.97075
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
-3.8614
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.50755
|
|
TWF2
|
twinfilin actin binding protein 2
|
-3.4512
|
|
CIAPIN1
|
cytokine induced apoptosis inhibitor 1
|
-3.0538
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.86955
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-2.78877
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.78445
|
|
SNX11
|
sorting nexin 11
|
-2.7622
|
|
CCNB1
|
cyclin B1
|
-2.7368
|
|
RNF167
|
ring finger protein 167
|
-2.708
|
|
ATF5
|
activating transcription factor 5
|
-2.6623
|
|
LRPAP1
|
low density lipoprotein receptor-related protein associated protein 1
|
-2.6057
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.55325
|
|
CHEK1
|
checkpoint kinase 1
|
-2.50848
|
|
HOXB7
|
homeobox B7
|
-2.30385
|
|
CNKSR3
|
CNKSR family member 3
|
-2.2477
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.2199
|
|
SCAND1
|
SCAN domain containing 1
|
-2.17755
|
|
AKAP8
|
A kinase (PRKA) anchor protein 8
|
-2.06912
|
|
AUP1
|
ancient ubiquitous protein 1
|
-2.0097
|
