CRCGN008_HEPG2_24H:D23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description citral 2.54 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

58 genes differentially expressed following the CRCGN008_HEPG2_24H:D23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 10.0
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 5.30115
PPP1R13B protein phosphatase 1, regulatory subunit 13B 5.13775
CHMP6 charged multivesicular body protein 6 5.06125
LCN2 lipocalin 2 4.66275
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 4.66275
PPARG peroxisome proliferator-activated receptor gamma 4.03945
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 3.81272
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 3.7087
CCNA1 cyclin A1 3.5132
ZFP36 ZFP36 ring finger protein 3.50315
TIAM1 T-cell lymphoma invasion and metastasis 1 3.471
GPER1 G protein-coupled estrogen receptor 1 3.40975
ADAT1 adenosine deaminase, tRNA-specific 1 2.8852
JADE2 jade family PHD finger 2 2.79857
PTK2 protein tyrosine kinase 2 2.69203
KIF20A kinesin family member 20A 2.64785
HLA-DRA major histocompatibility complex, class II, DR alpha 2.6382
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.5279
RPA3 replication protein A3, 14kDa 2.524
GPATCH8 G patch domain containing 8 2.43202
NMU neuromedin U 2.4159
KLHL9 kelch-like family member 9 2.35358
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 2.3444
CYCS cytochrome c, somatic 2.30545
AXIN1 axin 1 2.25595
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.25215
SCYL3 SCY1-like 3 (S. cerevisiae) 2.23493
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 2.2319
CDC45 cell division cycle 45 2.1643
EPHA3 EPH receptor A3 2.15672
TLR4 toll-like receptor 4 2.1178
JCAD junctional cadherin 5 associated 2.05615
CRTAP cartilage associated protein 2.03165
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.00658

decreased expression

Symbol Name Standardized Value
TSPAN4 tetraspanin 4 -4.8598
SLC35F2 solute carrier family 35, member F2 -4.82755
CCNB2 cyclin B2 -4.6831
HLA-DMA major histocompatibility complex, class II, DM alpha -4.54785
FASTKD5 FAST kinase domains 5 -4.5224
GNAS GNAS complex locus -4.11658
TLCD3A TLC domain containing 3A -3.4185
FBXL12 F-box and leucine-rich repeat protein 12 -3.27985
RNF167 ring finger protein 167 -3.12265
MAPK13 mitogen-activated protein kinase 13 -3.06305
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -3.01645
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -2.81378
OXA1L oxidase (cytochrome c) assembly 1-like -2.7556
PDZD2 PDZ domain containing 2 -2.609
PLA2G15 phospholipase A2, group XV -2.56135
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.4303
REEP5 receptor accessory protein 5 -2.3954
FUCA1 fucosidase, alpha-L- 1, tissue -2.2798
IER3 immediate early response 3 -2.23325
CDC25B cell division cycle 25B -2.08495
BMP4 bone morphogenetic protein 4 -2.08125
VCP valosin containing protein -2.03655
DCK deoxycytidine kinase -2.0029