| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | citral 1.27 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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79 genes differentially expressed following the CRCGN008_HEPG2_24H:D24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| C2CD2 | C2 calcium-dependent domain containing 2 | 5.1537 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 5.0258 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.98155 |
| ATP11B | ATPase, class VI, type 11B | 4.9768 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.80495 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.74945 |
| E2F2 | E2F transcription factor 2 | 4.735 |
| CBR3 | carbonyl reductase 3 | 4.43005 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.2417 |
| CHN1 | chimerin 1 | 3.70145 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.43295 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.2817 |
| TESK1 | testis-specific kinase 1 | 3.2616 |
| CYCS | cytochrome c, somatic | 3.1377 |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 | 3.09055 |
| TBP | TATA box binding protein | 2.9836 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.7097 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.68375 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.6469 |
| CEP57 | centrosomal protein 57kDa | 2.61583 |
| STK10 | serine/threonine kinase 10 | 2.59328 |
| AXIN1 | axin 1 | 2.5828 |
| CCNF | cyclin F | 2.5695 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.5597 |
| HSF4 | heat shock transcription factor 4 | 2.5402 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.52362 |
| EPHA3 | EPH receptor A3 | 2.52012 |
| NPHS1 | nephrosis 1, congenital, Finnish type (nephrin) | 2.4421 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) | 2.4086 |
| LFNG | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.16505 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.08437 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 | 2.08365 |
| MGAM | maltase-glucoamylase | 2.0797 |
| FAM110D | family with sequence similarity 110, member D | 2.078 |
| TAOK3 | TAO kinase 3 | 2.0743 |
| JADE2 | jade family PHD finger 2 | 2.07117 |
| PDLIM3 | PDZ and LIM domain 3 | 2.0629 |
| TCF15 | transcription factor 15 (basic helix-loop-helix) | 2.05855 |
| SOX12 | SRY (sex determining region Y)-box 12 | 2.0375 |
| PMS2 | PMS2 postmeiotic segregation increased 2 (S. cerevisiae) | 2.03285 |
| PRLH | prolactin releasing hormone | 2.0082 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HAT1 | histone acetyltransferase 1 | -5.5688 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -5.504 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -5.24385 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -5.23925 |
| LDHD | lactate dehydrogenase D | -5.20925 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -4.978 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -4.67845 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.62445 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -4.54975 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.5107 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -4.47242 |
| HEATR1 | HEAT repeat containing 1 | -3.9858 |
| CCNB1 | cyclin B1 | -3.7706 |
| CCP110 | centriolar coiled coil protein 110kDa | -3.32595 |
| HSPA8 | heat shock 70kDa protein 8 | -3.26342 |
| CAPNS1 | calpain, small subunit 1 | -3.24125 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.1229 |
| RNF167 | ring finger protein 167 | -3.07175 |
| SLC35F2 | solute carrier family 35, member F2 | -3.0051 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -2.9044 |
| TBCB | tubulin folding cofactor B | -2.83263 |
| SNX11 | sorting nexin 11 | -2.76333 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | -2.64805 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.62365 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.59755 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -2.57045 |
| ZNF146 | zinc finger protein 146 | -2.45535 |
| TXNDC9 | thioredoxin domain containing 9 | -2.32585 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain | -2.32435 |
| RBM42 | RNA binding motif protein 42 | -2.26245 |
| TNFSF12-TNFSF13 | TNFSF12-TNFSF13 readthrough | -2.22787 |
| SLC25A12 | solute carrier family 25 (aspartate/glutamate carrier), member 12 | -2.12205 |
| LNPEP | leucyl/cystinyl aminopeptidase | -2.12075 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | -2.1172 |
| ASL | argininosuccinate lyase | -2.0965 |
| PSENEN | presenilin enhancer gamma secretase subunit | -2.03545 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -2.02335 |
| CYB5R1 | cytochrome b5 reductase 1 | -2.01505 |