| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | [(phosphonomethyl)amino]acetic acid compound with 2-propanamine (1:1) 20.45 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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66 genes differentially expressed following the CRCGN008_HEPG2_24H:E01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABHD6 | abhydrolase domain containing 6 | 8.27592 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 6.12932 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 6.0676 |
| UBQLN2 | ubiquilin 2 | 5.14695 |
| ALDOC | aldolase C, fructose-bisphosphate | 4.96855 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.9127 |
| NOTCH1 | notch 1 | 4.87515 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.85615 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.5024 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.16885 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 4.15475 |
| PRR15L | proline rich 15-like | 4.14495 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 3.88525 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.82203 |
| NNT | nicotinamide nucleotide transhydrogenase | 3.76862 |
| CBR3 | carbonyl reductase 3 | 3.7535 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.72727 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 3.69675 |
| MOK | MOK protein kinase | 3.6764 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 3.02645 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.9108 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B | 2.63225 |
| TBPL1 | TBP-like 1 | 2.62845 |
| USP6NL | USP6 N-terminal like | 2.5599 |
| SFTPB | surfactant protein B | 2.49623 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.49612 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.49327 |
| ITM2A | integral membrane protein 2A | 2.47183 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.46215 |
| HEBP1 | heme binding protein 1 | 2.26825 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 2.17425 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.15605 |
| METRN | meteorin, glial cell differentiation regulator | 2.12235 |
| KDSR | 3-ketodihydrosphingosine reductase | 2.1152 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 2.0604 |
| CDC45 | cell division cycle 45 | 2.01675 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -6.45895 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -5.35235 |
| CCDC86 | coiled-coil domain containing 86 | -5.03985 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.83225 |
| LDHD | lactate dehydrogenase D | -4.706 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -4.64225 |
| FGFR4 | fibroblast growth factor receptor 4 | -4.0268 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.35355 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -3.26863 |
| RNF167 | ring finger protein 167 | -3.1583 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -3.1251 |
| FBXO7 | F-box protein 7 | -3.0528 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.0252 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.8569 |
| TOR1A | torsin family 1, member A (torsin A) | -2.76567 |
| SPAG4 | sperm associated antigen 4 | -2.6372 |
| PRPF4 | pre-mRNA processing factor 4 | -2.55325 |
| WNT7A | wingless-type MMTV integration site family, member 7A | -2.35495 |
| TES | testin LIM domain protein | -2.31537 |
| CLIC4 | chloride intracellular channel 4 | -2.28418 |
| TUFM | Tu translation elongation factor, mitochondrial | -2.20145 |
| SART1 | squamous cell carcinoma antigen recognized by T cells | -2.18685 |
| CRYM | crystallin, mu | -2.18645 |
| PLA2G15 | phospholipase A2, group XV | -2.1682 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate | -2.16295 |
| CGREF1 | cell growth regulator with EF-hand domain 1 | -2.10375 |
| FHL2 | four and a half LIM domains 2 | -2.0979 |
| FIBP | fibroblast growth factor (acidic) intracellular binding protein | -2.06025 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -2.03675 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -2.02505 |
