| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | [(phosphonomethyl)amino]acetic acid compound with 2-propanamine (1:1) 5.11 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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69 genes differentially expressed following the CRCGN008_HEPG2_24H:E03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHN1 | chimerin 1 | 6.984 |
| BZW2 | basic leucine zipper and W2 domains 2 | 5.23265 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 5.2198 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 5.08495 |
| HOXA10 | homeobox A10 | 4.62735 |
| GRWD1 | glutamate-rich WD repeat containing 1 | 4.4886 |
| RPL39L | ribosomal protein L39-like | 4.4749 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.90365 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 3.62044 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 3.3184 |
| GPATCH8 | G patch domain containing 8 | 3.0457 |
| METRN | meteorin, glial cell differentiation regulator | 3.0116 |
| RAB31 | RAB31, member RAS oncogene family | 2.88803 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.81445 |
| HEBP1 | heme binding protein 1 | 2.6848 |
| JADE2 | jade family PHD finger 2 | 2.64768 |
| TNIP1 | TNFAIP3 interacting protein 1 | 2.56405 |
| ALG3 | ALG3, alpha-1,3- mannosyltransferase | 2.4376 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 2.4249 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.41535 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.38863 |
| SCRN1 | secernin 1 | 2.38205 |
| TAC4 | tachykinin 4 (hemokinin) | 2.3162 |
| STXBP2 | syntaxin binding protein 2 | 2.2769 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 2.2065 |
| TXNL4B | thioredoxin-like 4B | 2.1973 |
| SKIC2 | SKI2 subunit of superkiller complex | 2.1215 |
| INSIG2 | insulin induced gene 2 | 2.1066 |
| NAA10 | N(alpha)-acetyltransferase 10, NatA catalytic subunit | 2.0407 |
| TDO2 | tryptophan 2,3-dioxygenase | 2.0231 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 2.0093 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| MAPK13 | mitogen-activated protein kinase 13 | -8.09743 |
| NUP85 | nucleoporin 85kDa | -5.1071 |
| GDF15 | growth differentiation factor 15 | -5.0 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -5.0 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.4457 |
| FASTKD5 | FAST kinase domains 5 | -4.25375 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -3.77378 |
| CCNB2 | cyclin B2 | -3.32695 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -3.29795 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -2.88738 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.8343 |
| ELMO3 | engulfment and cell motility 3 | -2.55825 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -2.53825 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.48683 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.4199 |
| TRIP6 | thyroid hormone receptor interactor 6 | -2.3913 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.3812 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -2.36345 |
| RASA4B | RAS p21 protein activator 4B | -2.3324 |
| TSKU | tsukushi, small leucine rich proteoglycan | -2.33145 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 | -2.32875 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -2.3266 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -2.3196 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 | -2.31945 |
| PRPF4 | pre-mRNA processing factor 4 | -2.29343 |
| CASKIN2 | CASK interacting protein 2 | -2.25275 |
| MRPS7 | mitochondrial ribosomal protein S7 | -2.1352 |
| CD58 | CD58 molecule | -2.12813 |
| TMEM94 | transmembrane protein 94 | -2.1052 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.07555 |
| ACAD8 | acyl-CoA dehydrogenase family, member 8 | -2.07405 |
| ZSCAN16 | zinc finger and SCAN domain containing 16 | -2.06025 |
| ACOX1 | acyl-CoA oxidase 1, palmitoyl | -2.0504 |
| MAPK4 | mitogen-activated protein kinase 4 | -2.0393 |
| FTSJ3 | FtsJ homolog 3 (E. coli) | -2.0376 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -2.029 |
| CEP131 | centrosomal protein 131kDa | -2.00115 |
