| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tin (ii) chloride 19.8 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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185 genes differentially expressed following the CRCGN008_HEPG2_24H:E08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYCS | cytochrome c, somatic | 6.1144 |
| TESK1 | testis-specific kinase 1 | 5.40005 |
| ALDOC | aldolase C, fructose-bisphosphate | 5.196 |
| CYB561 | cytochrome b561 | 4.35391 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 4.31385 |
| KIF5C | kinesin family member 5C | 4.2697 |
| MYLK | myosin light chain kinase | 4.207 |
| MOK | MOK protein kinase | 4.09685 |
| SSBP2 | single-stranded DNA binding protein 2 | 4.09032 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.95795 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 3.95423 |
| CNPY3 | canopy FGF signaling regulator 3 | 3.88345 |
| ZFP36 | ZFP36 ring finger protein | 3.7194 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 3.7152 |
| PRKCH | protein kinase C, eta | 3.7062 |
| LCN2 | lipocalin 2 | 3.3248 |
| E2F2 | E2F transcription factor 2 | 3.30425 |
| FAIM | Fas apoptotic inhibitory molecule | 3.2329 |
| CCNF | cyclin F | 3.23123 |
| RPIA | ribose 5-phosphate isomerase A | 3.1357 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.1178 |
| OXCT1 | 3-oxoacid CoA transferase 1 | 3.0729 |
| CBR3 | carbonyl reductase 3 | 2.8981 |
| FAAP100 | FA core complex associated protein 100 | 2.7973 |
| WASF3 | WAS protein family, member 3 | 2.79605 |
| MAP7 | microtubule-associated protein 7 | 2.79122 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) | 2.7684 |
| HEBP1 | heme binding protein 1 | 2.75435 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.69385 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.64335 |
| NMU | neuromedin U | 2.637 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide | 2.62045 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 2.6109 |
| FAM107A | family with sequence similarity 107, member A | 2.59882 |
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 2.5918 |
| RBM34 | RNA binding motif protein 34 | 2.56525 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.54695 |
| ZNF354A | zinc finger protein 354A | 2.52735 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 2.4652 |
| RNF44 | ring finger protein 44 | 2.4513 |
| GID8 | GID complex subunit 8 | 2.4441 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 2.42965 |
| TBPL1 | TBP-like 1 | 2.4045 |
| FCHO1 | FCH domain only 1 | 2.39695 |
| HIRA | histone cell cycle regulator | 2.38775 |
| NACAD | NAC alpha domain containing | 2.38205 |
| KIF20A | kinesin family member 20A | 2.377 |
| NLRP4 | NLR family, pyrin domain containing 4 | 2.3707 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.3572 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.3417 |
| TXNRD1 | thioredoxin reductase 1 | 2.33305 |
| CREB3L4 | cAMP responsive element binding protein 3-like 4 | 2.3241 |
| PRPSAP1 | phosphoribosyl pyrophosphate synthetase-associated protein 1 | 2.3223 |
| TMBIM4 | transmembrane BAX inhibitor motif containing 4 | 2.31805 |
| RGPD1 | RANBP2-like and GRIP domain containing 1 | 2.3032 |
| CT55 | cancer/testis antigen 55 | 2.2981 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 2.27315 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.27215 |
| PGBD5 | piggyBac transposable element derived 5 | 2.22232 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | 2.2196 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 2.21788 |
| ZIM3 | zinc finger, imprinted 3 | 2.2142 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.20947 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 2.19718 |
| CCDC91 | coiled-coil domain containing 91 | 2.1828 |
| CXCR2 | chemokine (C-X-C motif) receptor 2 | 2.1815 |
| STXBP1 | syntaxin binding protein 1 | 2.15055 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | 2.1414 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 | 2.13445 |
| UBE2Q1 | ubiquitin-conjugating enzyme E2Q family member 1 | 2.13295 |
| LRP10 | low density lipoprotein receptor-related protein 10 | 2.1315 |
| PLSCR1 | phospholipid scramblase 1 | 2.1268 |
| BAG3 | BCL2-associated athanogene 3 | 2.12105 |
| ADSS2 | adenylosuccinate synthase 2 | 2.12085 |
| NUCB2 | nucleobindin 2 | 2.1157 |
| CAPN1 | calpain 1, (mu/I) large subunit | 2.11475 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.08768 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 2.087 |
| PRKX | protein kinase, X-linked | 2.07868 |
| ZNF215 | zinc finger protein 215 | 2.0736 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | 2.04626 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 | 2.04555 |
| FAM193B | family with sequence similarity 193, member B | 2.033 |
| ZNRF2 | zinc and ring finger 2, E3 ubiquitin protein ligase | 2.0288 |
| CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 | 2.01275 |
| FES | FES proto-oncogene, tyrosine kinase | 2.0081 |
| EXOC3 | exocyst complex component 3 | 2.00485 |
| SLC25A44 | solute carrier family 25, member 44 | 2.00485 |
| TMEM132A | transmembrane protein 132A | 2.0047 |
| USP11 | ubiquitin specific peptidase 11 | 2.0025 |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter), member 3 | 2.00195 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 2.00025 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -10.0 |
| TLCD3A | TLC domain containing 3A | -4.83605 |
| SPAG4 | sperm associated antigen 4 | -4.82675 |
| ADI1 | acireductone dioxygenase 1 | -4.69665 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -4.60365 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.60245 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -4.52435 |
| CCNB2 | cyclin B2 | -4.46875 |
| CDC20 | cell division cycle 20 | -4.3123 |
| PCNA | proliferating cell nuclear antigen | -4.2674 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | -3.78065 |
| IFRD2 | interferon-related developmental regulator 2 | -3.5317 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -3.5194 |
| HEATR1 | HEAT repeat containing 1 | -3.51483 |
| LOC124907782 | dual specificity protein phosphatase 22 | -3.47075 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -3.3925 |
| SH3D19 | SH3 domain containing 19 | -3.33543 |
| NGRN | neugrin, neurite outgrowth associated | -3.2374 |
| RGS2 | regulator of G-protein signaling 2 | -3.1196 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | -3.005 |
| FHL2 | four and a half LIM domains 2 | -2.79045 |
| SNX11 | sorting nexin 11 | -2.7072 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.6895 |
| PRKG2 | protein kinase, cGMP-dependent, type II | -2.64415 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -2.6067 |
| WASHC4 | WASH complex subunit 4 | -2.57735 |
| TOR1A | torsin family 1, member A (torsin A) | -2.5676 |
| CD58 | CD58 molecule | -2.53528 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.53518 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -2.52185 |
| BZW2 | basic leucine zipper and W2 domains 2 | -2.4451 |
| LGMN | legumain | -2.4171 |
| NAT10 | N-acetyltransferase 10 (GCN5-related) | -2.40005 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | -2.39805 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.3798 |
| DOK2 | docking protein 2, 56kDa | -2.3721 |
| HOXA5 | homeobox A5 | -2.3624 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -2.359 |
| CYB561D2 | cytochrome b561 family, member D2 | -2.3497 |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) | -2.29945 |
| SLAMF1 | signaling lymphocytic activation molecule family member 1 | -2.29855 |
| BCL7B | B-cell CLL/lymphoma 7B | -2.2904 |
| ADGRA2 | adhesion G protein-coupled receptor A2 | -2.2778 |
| EIF2D | eukaryotic translation initiation factor 2D | -2.27765 |
| ATP8B4 | ATPase, class I, type 8B, member 4 | -2.2402 |
| CDC73 | cell division cycle 73 | -2.2221 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -2.2107 |
| TMEM14B | transmembrane protein 14B | -2.20675 |
| XPO4 | exportin 4 | -2.2054 |
| COG2 | component of oligomeric golgi complex 2 | -2.20015 |
| CTSG | cathepsin G | -2.1925 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.19175 |
| MYL11 | myosin light chain 11 | -2.18755 |
| LTA | lymphotoxin alpha | -2.18745 |
| TNNC2 | troponin C type 2 (fast) | -2.1814 |
| HNMT | histamine N-methyltransferase | -2.17382 |
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A | -2.1735 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -2.17055 |
| MYOZ1 | myozenin 1 | -2.16015 |
| KLHL21 | kelch-like family member 21 | -2.1591 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | -2.1526 |
| POGLUT2 | protein O-glucosyltransferase 2 | -2.14785 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -2.14555 |
| TNNI2 | troponin I type 2 (skeletal, fast) | -2.1383 |
| RFX7 | regulatory factor X, 7 | -2.13365 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C | -2.12615 |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | -2.1025 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -2.0925 |
| TEX10 | testis expressed 10 | -2.0879 |
| RYK | receptor-like tyrosine kinase | -2.08752 |
| EPS8L3 | EPS8-like 3 | -2.08705 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -2.08365 |
| COL5A2 | collagen, type V, alpha 2 | -2.08092 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -2.0768 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -2.07623 |
| CCDC7 | coiled-coil domain containing 7 | -2.0729 |
| INTS14 | integrator complex subunit 14 | -2.06575 |
| SFRP1 | secreted frizzled-related protein 1 | -2.0652 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -2.055 |
| RNF167 | ring finger protein 167 | -2.049 |
| ITGAV | integrin, alpha V | -2.04395 |
| MOXD1 | monooxygenase, DBH-like 1 | -2.03525 |
| PARG | poly (ADP-ribose) glycohydrolase | -2.03055 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 | -2.0298 |
| COA3 | cytochrome c oxidase assembly factor 3 | -2.02855 |
| FBRS | fibrosin | -2.02745 |
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 | -2.0266 |
| NKRF | NFKB repressing factor | -2.026 |
| TCTN1 | tectonic family member 1 | -2.02415 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -2.01413 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -2.01315 |
| CISH | cytokine inducible SH2-containing protein | -2.00435 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 | -2.00325 |
