| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tin (ii) chloride 9.9 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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91 genes differentially expressed following the CRCGN008_HEPG2_24H:E09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHN1 | chimerin 1 | 6.933 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.6972 |
| CHMP6 | charged multivesicular body protein 6 | 5.53895 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 5.45925 |
| STAP2 | signal transducing adaptor family member 2 | 5.3992 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.99135 |
| ATP11B | ATPase, class VI, type 11B | 4.93095 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.8795 |
| STK10 | serine/threonine kinase 10 | 4.86823 |
| ARL4C | ADP-ribosylation factor-like 4C | 4.84182 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 4.49655 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 4.2601 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 4.2213 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 4.21967 |
| CYCS | cytochrome c, somatic | 4.0004 |
| EGF | epidermal growth factor | 3.936 |
| LCN2 | lipocalin 2 | 3.78325 |
| ALDOC | aldolase C, fructose-bisphosphate | 3.7202 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.43543 |
| MDM4 | MDM4, p53 regulator | 3.4211 |
| RRAGA | Ras-related GTP binding A | 3.1183 |
| PRR15L | proline rich 15-like | 3.1073 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.92037 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 2.8677 |
| CORO1A | coronin, actin binding protein, 1A | 2.75235 |
| EPHA3 | EPH receptor A3 | 2.61193 |
| TXNL4B | thioredoxin-like 4B | 2.53945 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.46585 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 2.4498 |
| GPATCH8 | G patch domain containing 8 | 2.4164 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 2.39845 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 | 2.39155 |
| WDR19 | WD repeat domain 19 | 2.2675 |
| TAPT1 | transmembrane anterior posterior transformation 1 | 2.22385 |
| NMU | neuromedin U | 2.1411 |
| ADRA2A | adrenoceptor alpha 2A | 2.13525 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.12928 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | 2.112 |
| TOP6BL | TOP6B like initiator of meiotic double strand breaks | 2.09585 |
| LAMB3 | laminin, beta 3 | 2.08565 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.07825 |
| RNF139 | ring finger protein 139 | 2.06195 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 2.0386 |
| OXCT1 | 3-oxoacid CoA transferase 1 | 2.02655 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -7.7078 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -6.6932 |
| ISOC1 | isochorismatase domain containing 1 | -5.6684 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -5.28385 |
| CCDC86 | coiled-coil domain containing 86 | -5.2111 |
| LDHD | lactate dehydrogenase D | -5.1498 |
| GDF15 | growth differentiation factor 15 | -5.0 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -4.80695 |
| CCNB2 | cyclin B2 | -4.7794 |
| PCNA | proliferating cell nuclear antigen | -4.77245 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.5633 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -4.5622 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -4.5619 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -4.05035 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -4.02082 |
| RGS2 | regulator of G-protein signaling 2 | -3.433 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.42585 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | -3.07655 |
| TOR1A | torsin family 1, member A (torsin A) | -2.90633 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.8521 |
| WASHC4 | WASH complex subunit 4 | -2.80445 |
| ACTMAP | actin maturation protease | -2.7711 |
| SULT1C4 | sulfotransferase family, cytosolic, 1C, member 4 | -2.68925 |
| HSPA8 | heat shock 70kDa protein 8 | -2.64942 |
| RNF167 | ring finger protein 167 | -2.6484 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.35535 |
| MYL6B | myosin, light chain 6B, alkali, smooth muscle and non-muscle | -2.35135 |
| GAL3ST1 | galactose-3-O-sulfotransferase 1 | -2.3117 |
| TAOK3 | TAO kinase 3 | -2.30925 |
| CHEK1 | checkpoint kinase 1 | -2.27912 |
| COMMD9 | COMM domain containing 9 | -2.27845 |
| RANGRF | RAN guanine nucleotide release factor | -2.261 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -2.25807 |
| SCRG1 | stimulator of chondrogenesis 1 | -2.2577 |
| TRIM8 | tripartite motif containing 8 | -2.2429 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | -2.24155 |
| REEP5 | receptor accessory protein 5 | -2.20093 |
| RBM34 | RNA binding motif protein 34 | -2.18507 |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa | -2.15135 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.12902 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -2.10775 |
| SAC3D1 | SAC3 domain containing 1 | -2.1064 |
| PRPF19 | pre-mRNA processing factor 19 | -2.10375 |
| TGFB3 | transforming growth factor, beta 3 | -2.0787 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.0776 |
| TM6SF1 | transmembrane 6 superfamily member 1 | -2.0253 |
| TMEM186 | transmembrane protein 186 | -2.00025 |
