| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tin (ii) chloride 4.95 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
240 genes differentially expressed following the CRCGN008_HEPG2_24H:E10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 10.0 |
| PPARG | peroxisome proliferator-activated receptor gamma | 10.0 |
| SMIM40 | small integral membrane protein 40 | 8.0501 |
| SSBP2 | single-stranded DNA binding protein 2 | 7.4717 |
| TBPL1 | TBP-like 1 | 6.6367 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 5.7989 |
| CCNF | cyclin F | 5.5639 |
| LPAR2 | lysophosphatidic acid receptor 2 | 5.50805 |
| EPHA3 | EPH receptor A3 | 5.15397 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 4.82363 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 4.7728 |
| GRWD1 | glutamate-rich WD repeat containing 1 | 4.5781 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.3442 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 3.843 |
| PRKX | protein kinase, X-linked | 3.74825 |
| BAMBI | BMP and activin membrane-bound inhibitor | 3.5055 |
| ECD | ecdysoneless homolog (Drosophila) | 3.3444 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 3.2568 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 3.107 |
| CREB1 | cAMP responsive element binding protein 1 | 3.08515 |
| MANSC1 | MANSC domain containing 1 | 3.0309 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.9582 |
| CRTAP | cartilage associated protein | 2.951 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 2.8766 |
| KAT2B | K(lysine) acetyltransferase 2B | 2.8763 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | 2.8749 |
| SOD3 | superoxide dismutase 3, extracellular | 2.6945 |
| PTK2 | protein tyrosine kinase 2 | 2.68065 |
| AGBL5 | ATP/GTP binding protein-like 5 | 2.6806 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 2.6694 |
| ZAP70 | zeta-chain (TCR) associated protein kinase 70kDa | 2.6466 |
| PLAC1 | placenta-specific 1 | 2.5789 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | 2.5475 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.5469 |
| RABGAP1L | RAB GTPase activating protein 1-like | 2.5236 |
| CTSE | cathepsin E | 2.4764 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 2.4674 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 2.4603 |
| CARTPT | CART prepropeptide | 2.4402 |
| SOX5 | SRY (sex determining region Y)-box 5 | 2.4342 |
| ST8SIA1 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 | 2.4265 |
| RIT2 | Ras-like without CAAX 2 | 2.4247 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | 2.4191 |
| TBC1D19 | TBC1 domain family, member 19 | 2.4041 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D | 2.4027 |
| AMZ2 | archaelysin family metallopeptidase 2 | 2.3973 |
| CXCR2 | chemokine (C-X-C motif) receptor 2 | 2.3896 |
| PLPP1 | phospholipid phosphatase 1 | 2.3707 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | 2.3628 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 2.3622 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | 2.3591 |
| HSPA1A | heat shock 70kDa protein 1A | 2.3536 |
| NSG2 | neuronal vesicle trafficking associated 2 | 2.3312 |
| CD247 | CD247 molecule | 2.3238 |
| RGS4 | regulator of G-protein signaling 4 | 2.31617 |
| NAP1L3 | nucleosome assembly protein 1-like 3 | 2.294 |
| TMX2 | thioredoxin-related transmembrane protein 2 | 2.2675 |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 | 2.26635 |
| IPO13 | importin 13 | 2.2648 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | 2.2644 |
| CMTR1 | cap methyltransferase 1 | 2.2633 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 2.2535 |
| PIGK | phosphatidylinositol glycan anchor biosynthesis, class K | 2.2352 |
| DDX25 | DEAD (Asp-Glu-Ala-Asp) box helicase 25 | 2.2294 |
| ADCYAP1 | adenylate cyclase activating polypeptide 1 (pituitary) | 2.2294 |
| OGN | osteoglycin | 2.217 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 2.2121 |
| CEP63 | centrosomal protein 63kDa | 2.20725 |
| GARS1 | glycyl-tRNA synthetase 1 | 2.2024 |
| SCRG1 | stimulator of chondrogenesis 1 | 2.2019 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 2.20075 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.1964 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | 2.1902 |
| SPAG16 | sperm associated antigen 16 | 2.185 |
| COL9A1 | collagen, type IX, alpha 1 | 2.1833 |
| PVRIG | poliovirus receptor related immunoglobulin domain containing | 2.1814 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) | 2.1732 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 2.1714 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 2.16777 |
| SCN1A | sodium channel, voltage gated, type I alpha subunit | 2.1676 |
| PLCB4 | phospholipase C, beta 4 | 2.1651 |
| CCDC47 | coiled-coil domain containing 47 | 2.1571 |
| RAB23 | RAB23, member RAS oncogene family | 2.1556 |
| MTMR4 | myotubularin related protein 4 | 2.14365 |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 | 2.1284 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 2.1277 |
| DUOX2 | dual oxidase 2 | 2.113 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 2.1093 |
| CAPRIN2 | caprin family member 2 | 2.1022 |
| ANK2 | ankyrin 2, neuronal | 2.10115 |
| INSM1 | insulinoma-associated 1 | 2.0866 |
| KIR3DL1 | killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 | 2.08585 |
| CCDC85B | coiled-coil domain containing 85B | 2.0833 |
| PCDHGC3 | protocadherin gamma subfamily C, 3 | 2.07235 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 | 2.071 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 2.0675 |
| EEF1E1 | eukaryotic translation elongation factor 1 epsilon 1 | 2.0652 |
| NCALD | neurocalcin delta | 2.0652 |
| C1R | complement component 1, r subcomponent | 2.0562 |
| TRMT61B | tRNA methyltransferase 61B | 2.0531 |
| CD96 | CD96 molecule | 2.0479 |
| LPXN | leupaxin | 2.0474 |
| THBS4 | thrombospondin 4 | 2.0374 |
| MCM3 | minichromosome maintenance complex component 3 | 2.0362 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 2.036 |
| PRUNE2 | prune homolog 2 (Drosophila) | 2.03395 |
| ZNF440 | zinc finger protein 440 | 2.0276 |
| GDAP1 | ganglioside induced differentiation associated protein 1 | 2.0203 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | 2.0164 |
| F2RL2 | coagulation factor II (thrombin) receptor-like 2 | 2.0153 |
| PSME3 | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) | 2.01273 |
| THOC7 | THO complex 7 | 2.0086 |
| SYT13 | synaptotagmin XIII | 2.0071 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 2.0056 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | 2.0034 |
| GNAT3 | guanine nucleotide binding protein, alpha transducing 3 | 2.0032 |
| CRIPTO3 | cripto, EGF-CFC family member 3 | 2.0012 |
| TRIM23 | tripartite motif containing 23 | 2.00027 |
| Symbol | Name | Standardized Value |
|---|---|---|
| THAP11 | THAP domain containing 11 | -10.0 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -9.8737 |
| SLC35F2 | solute carrier family 35, member F2 | -7.2497 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -7.143 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -6.5744 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -5.9782 |
| WASHC4 | WASH complex subunit 4 | -5.4329 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -5.126 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.9972 |
| GLOD4 | glyoxalase domain containing 4 | -3.8354 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.769 |
| SETD1B | SET domain containing 1B | -3.6003 |
| APOE | apolipoprotein E | -3.5162 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -3.2829 |
| SEMA6C | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C | -3.0672 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -2.9575 |
| CIC | capicua transcriptional repressor | -2.8879 |
| GPR27 | G protein-coupled receptor 27 | -2.8544 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | -2.796 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -2.7909 |
| EMC6 | ER membrane protein complex subunit 6 | -2.789 |
| TMED1 | transmembrane emp24 protein transport domain containing 1 | -2.7709 |
| ZC3H4 | zinc finger CCCH-type containing 4 | -2.6925 |
| MGA | MGA, MAX dimerization protein | -2.685 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -2.6637 |
| DHRS4 | dehydrogenase/reductase (SDR family) member 4 | -2.657 |
| INO80D | INO80 complex subunit D | -2.6328 |
| PKD2L1 | polycystic kidney disease 2-like 1 | -2.6147 |
| CHSY1 | chondroitin sulfate synthase 1 | -2.5912 |
| APH1A | APH1A gamma secretase subunit | -2.5674 |
| SLC17A9 | solute carrier family 17 (vesicular nucleotide transporter), member 9 | -2.5655 |
| ABITRAM | actin binding transcription modulator | -2.5548 |
| FES | FES proto-oncogene, tyrosine kinase | -2.5161 |
| PRPF8 | pre-mRNA processing factor 8 | -2.5143 |
| ECE1 | endothelin converting enzyme 1 | -2.48515 |
| ZNF516 | zinc finger protein 516 | -2.4727 |
| BMP4 | bone morphogenetic protein 4 | -2.4571 |
| CDH22 | cadherin 22, type 2 | -2.4542 |
| MED9 | mediator complex subunit 9 | -2.4422 |
| LINS1 | lines homolog 1 | -2.4358 |
| FADD | Fas (TNFRSF6)-associated via death domain | -2.4302 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -2.3861 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 | -2.384 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | -2.3818 |
| TSC1 | tuberous sclerosis 1 | -2.3781 |
| CRY2 | cryptochrome circadian clock 2 | -2.3724 |
| DPY19L4 | dpy-19-like 4 (C. elegans) | -2.3714 |
| HMGCL | 3-hydroxymethyl-3-methylglutaryl-CoA lyase | -2.3699 |
| CCDC85C | coiled-coil domain containing 85C | -2.3332 |
| FOXC1 | forkhead box C1 | -2.3315 |
| ALKBH1 | alkB, alkylation repair homolog 1 (E. coli) | -2.329 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | -2.3261 |
| HOXA5 | homeobox A5 | -2.3154 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -2.299 |
| STRA6 | stimulated by retinoic acid 6 | -2.2888 |
| PRPF3 | pre-mRNA processing factor 3 | -2.2836 |
| ENOX2 | ecto-NOX disulfide-thiol exchanger 2 | -2.28357 |
| STIL | SCL/TAL1 interrupting locus | -2.2818 |
| ATXN2 | ataxin 2 | -2.2764 |
| ZNF629 | zinc finger protein 629 | -2.2756 |
| SPAG7 | sperm associated antigen 7 | -2.2699 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | -2.2644 |
| ANKRD46 | ankyrin repeat domain 46 | -2.2504 |
| MSX1 | msh homeobox 1 | -2.2365 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -2.2358 |
| CACNA1S | calcium channel, voltage-dependent, L type, alpha 1S subunit | -2.2287 |
| SETD3 | SET domain containing 3 | -2.2243 |
| SAA4 | serum amyloid A4, constitutive | -2.2219 |
| MRM3 | mitochondrial rRNA methyltransferase 3 | -2.2189 |
| HMGB3 | high mobility group box 3 | -2.2052 |
| FBRS | fibrosin | -2.1789 |
| GTPBP6 | GTP binding protein 6 (putative) | -2.1786 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 | -2.1665 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 | -2.1554 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 | -2.1547 |
| ASB13 | ankyrin repeat and SOCS box containing 13 | -2.151 |
| WFDC2 | WAP four-disulfide core domain 2 | -2.1468 |
| PCBP1 | poly(rC) binding protein 1 | -2.1458 |
| DDN | dendrin | -2.1404 |
| TMEM11 | transmembrane protein 11 | -2.1351 |
| SREBF1 | sterol regulatory element binding transcription factor 1 | -2.1243 |
| PUM1 | pumilio RNA-binding family member 1 | -2.1239 |
| RPIA | ribose 5-phosphate isomerase A | -2.1219 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -2.11793 |
| EIF4EBP3 | eukaryotic translation initiation factor 4E binding protein 3 | -2.1168 |
| GLRX5 | glutaredoxin 5 | -2.1135 |
| KCNC3 | potassium channel, voltage gated Shaw related subfamily C, member 3 | -2.1075 |
| PER1 | period circadian clock 1 | -2.10305 |
| CYP21A2 | cytochrome P450, family 21, subfamily A, polypeptide 2 | -2.1029 |
| ZNF79 | zinc finger protein 79 | -2.1003 |
| DHRS7B | dehydrogenase/reductase (SDR family) member 7B | -2.0976 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -2.0951 |
| NBPF19 | neuroblastoma breakpoint family, member 19 | -2.0944 |
| SAMD14 | sterile alpha motif domain containing 14 | -2.0923 |
| A4GALT | alpha 1,4-galactosyltransferase | -2.0894 |
| ENTREP1 | endosomal transmembrane epsin interactor 1 | -2.0892 |
| GLI3 | GLI family zinc finger 3 | -2.0859 |
| SHARPIN | SHANK-associated RH domain interactor | -2.0842 |
| ZNF189 | zinc finger protein 189 | -2.0826 |
| FXR2 | fragile X mental retardation, autosomal homolog 2 | -2.07415 |
| RPS9 | ribosomal protein S9 | -2.07375 |
| ATF5 | activating transcription factor 5 | -2.07165 |
| FANCC | Fanconi anemia, complementation group C | -2.0706 |
| ABRAXAS2 | abraxas 2, BRISC complex subunit | -2.06865 |
| BORCS6 | BLOC-1 related complex subunit 6 | -2.0681 |
| NAA35 | N(alpha)-acetyltransferase 35, NatC auxiliary subunit | -2.0629 |
| CNGB3 | cyclic nucleotide gated channel beta 3 | -2.0621 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | -2.0579 |
| ATF4 | activating transcription factor 4 | -2.0573 |
| PTCH2 | patched 2 | -2.0444 |
| STARD8 | StAR-related lipid transfer (START) domain containing 8 | -2.0412 |
| LIN7A | lin-7 homolog A (C. elegans) | -2.0373 |
| ST20-MTHFS | ST20-MTHFS readthrough | -2.0358 |
| NECAP2 | NECAP endocytosis associated 2 | -2.0348 |
| ADGRE1 | adhesion G protein-coupled receptor E1 | -2.0297 |
| F7 | coagulation factor VII (serum prothrombin conversion accelerator) | -2.0243 |
| ATP8B4 | ATPase, class I, type 8B, member 4 | -2.0222 |
| SLC13A2 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 | -2.0157 |
| VWA8 | von Willebrand factor A domain containing 8 | -2.01015 |
| MERTK | MER proto-oncogene, tyrosine kinase | -2.009 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -2.0078 |
| MICA | MHC class I polypeptide-related sequence A | -2.0029 |
