| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tin (ii) chloride 2.48 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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82 genes differentially expressed following the CRCGN008_HEPG2_24H:E11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYCS | cytochrome c, somatic | 6.3151 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 6.14865 |
| ADRB2 | adrenoceptor beta 2, surface | 6.12245 |
| E2F2 | E2F transcription factor 2 | 5.74585 |
| STAP2 | signal transducing adaptor family member 2 | 5.6795 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.60115 |
| KLHL21 | kelch-like family member 21 | 5.56815 |
| AMDHD2 | amidohydrolase domain containing 2 | 5.26525 |
| PMM2 | phosphomannomutase 2 | 4.65025 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.6363 |
| ABHD6 | abhydrolase domain containing 6 | 3.70203 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.67062 |
| HSPA1A | heat shock 70kDa protein 1A | 3.4852 |
| SHB | Src homology 2 domain containing adaptor protein B | 3.4224 |
| TBPL1 | TBP-like 1 | 3.3299 |
| GPC1 | glypican 1 | 3.2853 |
| NNT | nicotinamide nucleotide transhydrogenase | 3.20213 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 3.1049 |
| MAP7 | microtubule-associated protein 7 | 2.9952 |
| MEST | mesoderm specific transcript | 2.9658 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 2.6753 |
| USP6NL | USP6 N-terminal like | 2.62025 |
| IL17B | interleukin 17B | 2.61085 |
| TBP | TATA box binding protein | 2.59705 |
| FPGS | folylpolyglutamate synthase | 2.5941 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.51382 |
| PEX6 | peroxisomal biogenesis factor 6 | 2.4233 |
| KCNQ4 | potassium channel, voltage gated KQT-like subfamily Q, member 4 | 2.4021 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 2.33858 |
| MAPK4 | mitogen-activated protein kinase 4 | 2.3341 |
| TRIM13 | tripartite motif containing 13 | 2.20845 |
| PITX1 | paired-like homeodomain 1 | 2.19385 |
| COL11A2 | collagen, type XI, alpha 2 | 2.17045 |
| TNP1 | transition protein 1 (during histone to protamine replacement) | 2.17045 |
| INAVA | innate immunity activator | 2.15835 |
| RGS1 | regulator of G-protein signaling 1 | 2.1431 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 2.11973 |
| LOC124900388 | uncharacterized LOC124900388 | 2.0962 |
| HS6ST1 | heparan sulfate 6-O-sulfotransferase 1 | 2.07265 |
| MPC1 | mitochondrial pyruvate carrier 1 | 2.06535 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 2.0534 |
| SELENOW | selenoprotein W | 2.04065 |
| EFNA1 | ephrin-A1 | 2.0011 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC35F2 | solute carrier family 35, member F2 | -8.7758 |
| ZNF586 | zinc finger protein 586 | -8.2587 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -5.45595 |
| TRIB3 | tribbles pseudokinase 3 | -5.37315 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -5.33725 |
| FASTKD5 | FAST kinase domains 5 | -4.9221 |
| CCDC86 | coiled-coil domain containing 86 | -4.66275 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.6087 |
| SPAG4 | sperm associated antigen 4 | -4.5682 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -4.4646 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -4.22643 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -3.80975 |
| SCCPDH | saccharopine dehydrogenase (putative) | -3.63313 |
| RNF167 | ring finger protein 167 | -3.30295 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | -3.0177 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.00425 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.7906 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -2.7877 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.75275 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -2.7112 |
| ZNF134 | zinc finger protein 134 | -2.62305 |
| CCNB1 | cyclin B1 | -2.60485 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.58105 |
| SETD5 | SET domain containing 5 | -2.56905 |
| SCAND1 | SCAN domain containing 1 | -2.5518 |
| TXNDC9 | thioredoxin domain containing 9 | -2.52732 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.5024 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.45802 |
| HSPA8 | heat shock 70kDa protein 8 | -2.35807 |
| ZRSR2 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 | -2.3011 |
| CCNH | cyclin H | -2.2299 |
| ADRM1 | adhesion regulating molecule 1 | -2.18945 |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase | -2.17815 |
| CD1B | CD1b molecule | -2.1128 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.04542 |
| DCK | deoxycytidine kinase | -2.0394 |
| PSME3IP1 | proteasome activator subunit 3 interacting protein 1 | -2.0266 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -2.02 |
| BCL9 | B-cell CLL/lymphoma 9 | -2.0069 |
