| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tin (ii) chloride 1.24 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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65 genes differentially expressed following the CRCGN008_HEPG2_24H:E12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ATP11B | ATPase, class VI, type 11B | 5.1658 |
| NOSIP | nitric oxide synthase interacting protein | 4.865 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.6386 |
| LSR | lipolysis stimulated lipoprotein receptor | 4.46655 |
| ABHD6 | abhydrolase domain containing 6 | 4.35668 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 4.0464 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.64028 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.14913 |
| CYCS | cytochrome c, somatic | 3.10825 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.10685 |
| MAP7 | microtubule-associated protein 7 | 2.95593 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.88147 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.85475 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.7072 |
| PLSCR1 | phospholipid scramblase 1 | 2.6651 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) | 2.5104 |
| KIF20A | kinesin family member 20A | 2.5031 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 2.32415 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.27485 |
| CDCA4 | cell division cycle associated 4 | 2.25235 |
| STX1A | syntaxin 1A (brain) | 2.1542 |
| GRB10 | growth factor receptor-bound protein 10 | 2.0793 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.04253 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.0299 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 2.02735 |
| PRODH | proline dehydrogenase (oxidase) 1 | 2.01675 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.0031 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UGDH | UDP-glucose 6-dehydrogenase | -5.13795 |
| CCDC86 | coiled-coil domain containing 86 | -5.0946 |
| SLC35F2 | solute carrier family 35, member F2 | -5.08 |
| GNAS | GNAS complex locus | -5.05261 |
| PCNA | proliferating cell nuclear antigen | -5.0 |
| LDHD | lactate dehydrogenase D | -4.97675 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -4.8245 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.3935 |
| FASTKD5 | FAST kinase domains 5 | -4.24815 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -4.105 |
| GDF15 | growth differentiation factor 15 | -3.9785 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -3.8893 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | -3.71225 |
| HMG20B | high mobility group 20B | -3.60882 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.5516 |
| RGS2 | regulator of G-protein signaling 2 | -3.08005 |
| TLCD3A | TLC domain containing 3A | -3.0669 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.9444 |
| TES | testin LIM domain protein | -2.72705 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.6827 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -2.5998 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -2.56505 |
| ICAM3 | intercellular adhesion molecule 3 | -2.5649 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -2.52212 |
| WASHC4 | WASH complex subunit 4 | -2.42198 |
| ASTN1 | astrotactin 1 | -2.30595 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | -2.28865 |
| RPE65 | retinal pigment epithelium-specific protein 65kDa | -2.1863 |
| CD58 | CD58 molecule | -2.14952 |
| SNTG1 | syntrophin, gamma 1 | -2.1385 |
| CNPY3-GNMT | CNPY3-GNMT readthrough | -2.1282 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -2.1042 |
| ZNF507 | zinc finger protein 507 | -2.0986 |
| DCK | deoxycytidine kinase | -2.09675 |
| LGSN | lengsin, lens protein with glutamine synthetase domain | -2.06745 |
| CNGA3 | cyclic nucleotide gated channel alpha 3 | -2.0633 |
| MEIS2 | Meis homeobox 2 | -2.04315 |
| POU1F1 | POU class 1 homeobox 1 | -2.02565 |
