| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | diphenyl-p-phenylenediamine 1.24 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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64 genes differentially expressed following the CRCGN008_HEPG2_24H:E18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 5.3954 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 5.04 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.7605 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.33585 |
| CCL2 | chemokine (C-C motif) ligand 2 | 4.3106 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 4.18785 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 3.95078 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.89647 |
| CDCA4 | cell division cycle associated 4 | 3.85085 |
| CHN1 | chimerin 1 | 3.47025 |
| MAP7 | microtubule-associated protein 7 | 3.27682 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 3.1609 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.95662 |
| CHEK2 | checkpoint kinase 2 | 2.74297 |
| COPS7A | COP9 signalosome subunit 7A | 2.72265 |
| TBC1D31 | TBC1 domain family, member 31 | 2.64925 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 2.63495 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 2.46677 |
| EPHA3 | EPH receptor A3 | 2.44493 |
| HOOK2 | hook microtubule-tethering protein 2 | 2.37052 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 2.3559 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.3331 |
| POU4F1 | POU class 4 homeobox 1 | 2.273 |
| MOGAT1 | monoacylglycerol O-acyltransferase 1 | 2.13635 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 | 2.13065 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.07835 |
| PIGK | phosphatidylinositol glycan anchor biosynthesis, class K | 2.06145 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 | 2.05025 |
| PSG6 | pregnancy specific beta-1-glycoprotein 6 | 2.04418 |
| NOSIP | nitric oxide synthase interacting protein | 2.04085 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.00967 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 2.0083 |
| Symbol | Name | Standardized Value |
|---|---|---|
| OXA1L | oxidase (cytochrome c) assembly 1-like | -6.3751 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -5.3853 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -5.36995 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.0711 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.9792 |
| NGRN | neugrin, neurite outgrowth associated | -4.74155 |
| LDHD | lactate dehydrogenase D | -4.66275 |
| CD320 | CD320 molecule | -4.636 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -4.6116 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -4.6054 |
| TLCD3A | TLC domain containing 3A | -4.59135 |
| ILK | integrin-linked kinase | -4.36185 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.3097 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -4.30555 |
| MAPK13 | mitogen-activated protein kinase 13 | -4.13723 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -4.1286 |
| FGFR4 | fibroblast growth factor receptor 4 | -4.0442 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -3.0859 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.0555 |
| WASHC4 | WASH complex subunit 4 | -2.93303 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.82665 |
| TWF2 | twinfilin actin binding protein 2 | -2.7828 |
| HSPA8 | heat shock 70kDa protein 8 | -2.6813 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.483 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.47468 |
| RHOF | ras homolog family member F (in filopodia) | -2.28825 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.26638 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | -2.20475 |
| NDUFA10 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa | -2.0999 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | -2.066 |
| TUBA3C | tubulin, alpha 3c | -2.04795 |
| DLGAP3 | discs, large (Drosophila) homolog-associated protein 3 | -2.01255 |
