CRCGN008_HEPG2_24H:E22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description diethylstilbestrol 4.97 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

68 genes differentially expressed following the CRCGN008_HEPG2_24H:E22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ZNF589 zinc finger protein 589 5.56012
UBQLN2 ubiquilin 2 5.11015
ATP11B ATPase, class VI, type 11B 4.79605
NUP133 nucleoporin 133kDa 4.6351
VAV3 vav 3 guanine nucleotide exchange factor 4.0886
IDE insulin-degrading enzyme 3.96797
PEX11A peroxisomal biogenesis factor 11 alpha 3.41582
KLHL9 kelch-like family member 9 3.20813
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.9415
CHN1 chimerin 1 2.8758
SSBP2 single-stranded DNA binding protein 2 2.6158
TGFB3 transforming growth factor, beta 3 2.58375
PLSCR3 phospholipid scramblase 3 2.53458
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 2.5238
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.4821
BPHL biphenyl hydrolase-like (serine hydrolase) 2.3874
SATB1 SATB homeobox 1 2.3591
RANBP6 RAN binding protein 6 2.34585
JADE2 jade family PHD finger 2 2.32277
AXIN1 axin 1 2.2985
HSPA1A heat shock 70kDa protein 1A 2.291
POGK pogo transposable element with KRAB domain 2.0494
ZIC1 Zic family member 1 2.01355
ARL4A ADP-ribosylation factor-like 4A 2.00335

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -10.0
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -6.2102
ZNF586 zinc finger protein 586 -5.52315
OXA1L oxidase (cytochrome c) assembly 1-like -5.15415
CD320 CD320 molecule -4.9648
LDHD lactate dehydrogenase D -4.82645
HAT1 histone acetyltransferase 1 -4.5644
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -4.55955
DCK deoxycytidine kinase -4.3201
RGS2 regulator of G-protein signaling 2 -4.0859
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -3.2756
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -3.2529
ACAA1 acetyl-CoA acyltransferase 1 -2.92143
SCAND1 SCAN domain containing 1 -2.8603
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -2.6775
ZNF660-ZNF197 ZNF660-ZNF197 readthrough -2.67175
CHIC2 cysteine-rich hydrophobic domain 2 -2.65325
DERA deoxyribose-phosphate aldolase (putative) -2.5054
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) -2.48655
PDHX pyruvate dehydrogenase complex, component X -2.4795
PRPF4 pre-mRNA processing factor 4 -2.45905
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase -2.3959
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit -2.35895
NKX2-8 NK2 homeobox 8 -2.34835
ZBP1 Z-DNA binding protein 1 -2.31395
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F -2.2952
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase) -2.2751
S1PR2 sphingosine-1-phosphate receptor 2 -2.2705
S100PBP S100P binding protein -2.19525
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.172
THAP4 THAP domain containing 4 -2.12775
FBXO24 F-box protein 24 -2.0918
MUL1 mitochondrial E3 ubiquitin protein ligase 1 -2.0752
B2M beta-2-microglobulin -2.068
KLF2 Kruppel-like factor 2 -2.06295
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa -2.05615
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -2.05275
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 -2.0416
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 -2.0351
UBIAD1 UbiA prenyltransferase domain containing 1 -2.02805
TSHZ2 teashirt zinc finger homeobox 2 -2.01725
AMELX amelogenin, X-linked -2.0145
CCNC cyclin C -2.0083
HHAT hedgehog acyltransferase -2.0058