CRCGN008_HEPG2_24H:E23 Gene Set
Genes
40 genes differentially expressed following the CRCGN008_HEPG2_24H:E23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHN1
|
chimerin 1
|
7.58925
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.82685
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.6482
|
|
MYLK
|
myosin light chain kinase
|
4.505
|
|
MICALL1
|
MICAL-like 1
|
4.1827
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
3.90835
|
|
EDN1
|
endothelin 1
|
3.85365
|
|
APBB2
|
amyloid beta (A4) precursor protein-binding, family B, member 2
|
3.3033
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
3.15433
|
|
TXNL4B
|
thioredoxin-like 4B
|
3.10305
|
|
MAP7
|
microtubule-associated protein 7
|
3.09725
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.99405
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.7681
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
2.73155
|
|
KLHL9
|
kelch-like family member 9
|
2.69082
|
|
HS2ST1
|
heparan sulfate 2-O-sulfotransferase 1
|
2.67962
|
|
CYCS
|
cytochrome c, somatic
|
2.34815
|
|
ARID4B
|
AT rich interactive domain 4B (RBP1-like)
|
2.21125
|
|
STXBP2
|
syntaxin binding protein 2
|
2.1294
|
|
ECD
|
ecdysoneless homolog (Drosophila)
|
2.1017
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-5.36575
|
|
LDHD
|
lactate dehydrogenase D
|
-4.82795
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-4.0827
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-3.8624
|
|
CCNB2
|
cyclin B2
|
-3.7724
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.6621
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-3.20083
|
|
GDF15
|
growth differentiation factor 15
|
-3.1094
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.0012
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.77865
|
|
PGM1
|
phosphoglucomutase 1
|
-2.60495
|
|
ATF5
|
activating transcription factor 5
|
-2.51198
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.48265
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.4338
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.37583
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.375
|
|
IGF2BP2
|
insulin-like growth factor 2 mRNA binding protein 2
|
-2.34535
|
|
LRPAP1
|
low density lipoprotein receptor-related protein associated protein 1
|
-2.30555
|
|
ACAN
|
aggrecan
|
-2.05202
|
|
MPV17L-BMERB1
|
MPV17L-BMERB1 readthrough
|
-2.03015
|
