| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | diethylstilbestrol 1.24 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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65 genes differentially expressed following the CRCGN008_HEPG2_24H:E24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYLK | myosin light chain kinase | 5.03895 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 4.9726 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.8964 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 4.7672 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 4.67015 |
| RAI14 | retinoic acid induced 14 | 4.59045 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 4.43945 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.2764 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 3.90945 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 3.77302 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.75432 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.7258 |
| FZD7 | frizzled class receptor 7 | 3.62738 |
| LOC122526780 | uncharacterized LOC122526780 | 3.60435 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 3.26075 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | 3.0916 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 3.08023 |
| CHEK2 | checkpoint kinase 2 | 2.6521 |
| CYCS | cytochrome c, somatic | 2.4984 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 | 2.4008 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 2.3744 |
| LCN2 | lipocalin 2 | 2.3716 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 2.3563 |
| AIMP2 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 | 2.28597 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 2.2802 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 2.22045 |
| USP6NL | USP6 N-terminal like | 2.1909 |
| EPHA3 | EPH receptor A3 | 2.13922 |
| IPO13 | importin 13 | 2.11485 |
| OSBPL11 | oxysterol binding protein-like 11 | 2.1106 |
| TEAD4 | TEA domain family member 4 | 2.10392 |
| CD1D | CD1d molecule | 2.10275 |
| COPS7A | COP9 signalosome subunit 7A | 2.05545 |
| ZIC1 | Zic family member 1 | 2.03205 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.0232 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -5.2315 |
| PCNA | proliferating cell nuclear antigen | -5.0 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.98335 |
| MAP7 | microtubule-associated protein 7 | -4.9795 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.5989 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.36155 |
| UGDH | UDP-glucose 6-dehydrogenase | -4.21415 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.0876 |
| CLIC4 | chloride intracellular channel 4 | -3.9782 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.90112 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.87897 |
| CCNB2 | cyclin B2 | -3.861 |
| TLCD3A | TLC domain containing 3A | -3.7446 |
| PRPF4 | pre-mRNA processing factor 4 | -3.48755 |
| ZNF586 | zinc finger protein 586 | -3.3395 |
| YME1L1 | YME1-like 1 ATPase | -3.32302 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -2.89005 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.8014 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -2.6946 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -2.534 |
| REEP5 | receptor accessory protein 5 | -2.33693 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.3125 |
| TBKBP1 | TBK1 binding protein 1 | -2.2811 |
| CNTN1 | contactin 1 | -2.26305 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -2.21203 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -2.1349 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) | -2.12645 |
| USP20 | ubiquitin specific peptidase 20 | -2.10355 |
| GLO1 | glyoxalase I | -2.0581 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.05025 |
