CRCGN008_HEPG2_24H:F04 Gene Set
Genes
48 genes differentially expressed following the CRCGN008_HEPG2_24H:F04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MYLK
|
myosin light chain kinase
|
10.0
|
|
RPL39L
|
ribosomal protein L39-like
|
4.59295
|
|
ATP11B
|
ATPase, class VI, type 11B
|
4.56335
|
|
ARL4C
|
ADP-ribosylation factor-like 4C
|
4.49055
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
4.18655
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.0928
|
|
VGLL4
|
vestigial-like family member 4
|
3.76638
|
|
H2BC12
|
H2B clustered histone 12
|
3.70005
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.4331
|
|
MAP7
|
microtubule-associated protein 7
|
3.40785
|
|
CTSL
|
cathepsin L
|
3.39875
|
|
CDCA4
|
cell division cycle associated 4
|
3.39215
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
3.34185
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
3.02905
|
|
CCNF
|
cyclin F
|
2.6323
|
|
GPATCH8
|
G patch domain containing 8
|
2.62462
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
2.4675
|
|
STXBP2
|
syntaxin binding protein 2
|
2.454
|
|
SCRN1
|
secernin 1
|
2.3998
|
|
ATP8B1
|
ATPase, aminophospholipid transporter, class I, type 8B, member 1
|
2.2036
|
|
PIK3CA
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
|
2.16185
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.08285
|
|
ITM2A
|
integral membrane protein 2A
|
2.08195
|
|
ADIRF
|
adipogenesis regulatory factor
|
2.0567
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.03715
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLCD3A
|
TLC domain containing 3A
|
-5.4796
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.2233
|
|
TIMM9
|
translocase of inner mitochondrial membrane 9 homolog (yeast)
|
-5.0
|
|
GOLT1B
|
golgi transport 1B
|
-4.9689
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-4.8579
|
|
LDHD
|
lactate dehydrogenase D
|
-4.776
|
|
FASTKD5
|
FAST kinase domains 5
|
-4.42805
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-3.95725
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.91295
|
|
PEG10
|
paternally expressed 10
|
-3.10232
|
|
CHEK1
|
checkpoint kinase 1
|
-2.87897
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-2.80845
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.69635
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.5455
|
|
CHIC2
|
cysteine-rich hydrophobic domain 2
|
-2.4654
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.3203
|
|
RNF167
|
ring finger protein 167
|
-2.1038
|
|
GABPA
|
GA binding protein transcription factor, alpha subunit 60kDa
|
-2.09975
|
|
P2RX5
|
purinergic receptor P2X, ligand gated ion channel, 5
|
-2.0931
|
|
GPATCH2
|
G patch domain containing 2
|
-2.0555
|
|
LOX
|
lysyl oxidase
|
-2.02767
|
|
ERO1A
|
endoplasmic reticulum oxidoreductase 1 alpha
|
-2.00555
|
|
SLC19A2
|
solute carrier family 19 (thiamine transporter), member 2
|
-2.0007
|
