| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-butyl chloride 2.55 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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63 genes differentially expressed following the CRCGN008_HEPG2_24H:F05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPER1 | G protein-coupled estrogen receptor 1 | 7.81547 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 5.66355 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 5.30825 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 4.96245 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.6999 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 4.4305 |
| LOC122526780 | uncharacterized LOC122526780 | 4.08085 |
| PRKCH | protein kinase C, eta | 4.00597 |
| KIF5C | kinesin family member 5C | 3.39145 |
| SNX7 | sorting nexin 7 | 3.26865 |
| JADE2 | jade family PHD finger 2 | 3.03877 |
| LPAR2 | lysophosphatidic acid receptor 2 | 3.02973 |
| TBP | TATA box binding protein | 3.0102 |
| SH3D19 | SH3 domain containing 19 | 2.77953 |
| NOSIP | nitric oxide synthase interacting protein | 2.7774 |
| GPATCH8 | G patch domain containing 8 | 2.77515 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.76145 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.68928 |
| NRSN2 | neurensin 2 | 2.65985 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.56887 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.53917 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.31145 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 2.2932 |
| EPHA3 | EPH receptor A3 | 2.23463 |
| HMGB2 | high mobility group box 2 | 2.2176 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 2.18107 |
| ATP4A | ATPase, H+/K+ exchanging, alpha polypeptide | 2.0795 |
| NXF2B | nuclear RNA export factor 2B | 2.01345 |
| HEBP1 | heme binding protein 1 | 2.00585 |
| UBE2V2 | ubiquitin-conjugating enzyme E2 variant 2 | 2.0031 |
| Symbol | Name | Standardized Value |
|---|---|---|
| OXA1L | oxidase (cytochrome c) assembly 1-like | -6.43455 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -5.43405 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -5.17025 |
| ZNF586 | zinc finger protein 586 | -5.15435 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -5.1051 |
| LDHD | lactate dehydrogenase D | -4.99055 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.9815 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.9006 |
| DNM1L | dynamin 1-like | -4.77335 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -4.67965 |
| CCNB2 | cyclin B2 | -4.66275 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.6624 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.57815 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -4.1378 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.89667 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.8166 |
| PRPF4 | pre-mRNA processing factor 4 | -3.70662 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -3.48625 |
| TCTN1 | tectonic family member 1 | -3.40835 |
| CCNB1 | cyclin B1 | -3.13895 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.10595 |
| PGM1 | phosphoglucomutase 1 | -3.0758 |
| SESN1 | sestrin 1 | -2.75815 |
| MRPS7 | mitochondrial ribosomal protein S7 | -2.5107 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | -2.44275 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.31815 |
| NARS1 | asparaginyl-tRNA synthetase 1 | -2.22405 |
| HADHB | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit | -2.16275 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.1081 |
| DCK | deoxycytidine kinase | -2.09525 |
| STOML2 | stomatin (EPB72)-like 2 | -2.06355 |
| FAM107A | family with sequence similarity 107, member A | -2.03367 |
| PGAP4 | post-GPI attachment to proteins GalNAc transferase 4 | -2.0037 |
