CRCGN008_HEPG2_24H:F06 Gene Set
Genes
50 genes differentially expressed following the CRCGN008_HEPG2_24H:F06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GPER1
|
G protein-coupled estrogen receptor 1
|
7.39657
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
5.1412
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
4.9007
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.8115
|
|
MYLK
|
myosin light chain kinase
|
4.783
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.68545
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.4387
|
|
LCN2
|
lipocalin 2
|
4.19045
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.95965
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.69428
|
|
EVL
|
Enah/Vasp-like
|
3.685
|
|
PRR15L
|
proline rich 15-like
|
3.4909
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.4375
|
|
VGLL4
|
vestigial-like family member 4
|
3.31098
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
3.2499
|
|
EGF
|
epidermal growth factor
|
3.12005
|
|
PARP2
|
poly (ADP-ribose) polymerase 2
|
2.87333
|
|
CHN1
|
chimerin 1
|
2.63085
|
|
SLC37A4
|
solute carrier family 37 (glucose-6-phosphate transporter), member 4
|
2.50183
|
|
JADE2
|
jade family PHD finger 2
|
2.47885
|
|
TBP
|
TATA box binding protein
|
2.2164
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
2.18745
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
2.1703
|
|
NAV2
|
neuron navigator 2
|
2.14955
|
|
ATP6V0E2
|
ATPase, H+ transporting V0 subunit e2
|
2.0979
|
|
APOD
|
apolipoprotein D
|
2.09555
|
|
SLC66A2
|
solute carrier family 66 member 2
|
2.01705
|
|
APOM
|
apolipoprotein M
|
2.01645
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
MAPK13
|
mitogen-activated protein kinase 13
|
-8.22277
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.33725
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-5.0812
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-4.88325
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-4.8745
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.83225
|
|
LDHD
|
lactate dehydrogenase D
|
-4.7091
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.1024
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-3.8953
|
|
CCNB1
|
cyclin B1
|
-3.72825
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-3.16928
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.94675
|
|
CCNH
|
cyclin H
|
-2.65635
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.58885
|
|
CYP26A1
|
cytochrome P450, family 26, subfamily A, polypeptide 1
|
-2.55205
|
|
RBM34
|
RNA binding motif protein 34
|
-2.49785
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.32242
|
|
GDPD2
|
glycerophosphodiester phosphodiesterase domain containing 2
|
-2.22685
|
|
GSDMD
|
gasdermin D
|
-2.2229
|
|
GCH1
|
GTP cyclohydrolase 1
|
-2.16075
|
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor)
|
-2.09939
|
|
LY6D
|
lymphocyte antigen 6 complex, locus D
|
-2.0139
|
