| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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120 genes differentially expressed following the CRCGN008_HEPG2_24H:F07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| E2F2 | E2F transcription factor 2 | 5.43655 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.94335 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.92525 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.91945 |
| PRKCD | protein kinase C, delta | 4.8358 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.8234 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 4.81685 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 4.75235 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.69835 |
| STK10 | serine/threonine kinase 10 | 4.48147 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 4.4777 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.30478 |
| CEP57 | centrosomal protein 57kDa | 4.29267 |
| CCNA1 | cyclin A1 | 3.7703 |
| NOSIP | nitric oxide synthase interacting protein | 3.7465 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.6284 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 2.94035 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.89588 |
| HEBP1 | heme binding protein 1 | 2.84805 |
| H2BC12 | H2B clustered histone 12 | 2.7381 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 2.72575 |
| KLHL9 | kelch-like family member 9 | 2.66512 |
| KIF20A | kinesin family member 20A | 2.6111 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.5718 |
| MAP7 | microtubule-associated protein 7 | 2.5678 |
| RRAGA | Ras-related GTP binding A | 2.5677 |
| CENPM | centromere protein M | 2.54585 |
| FGGY | FGGY carbohydrate kinase domain containing | 2.5246 |
| FADD | Fas (TNFRSF6)-associated via death domain | 2.50965 |
| DUOX1 | dual oxidase 1 | 2.4145 |
| PRKCZ | protein kinase C, zeta | 2.4056 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 2.40195 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 | 2.3345 |
| BAX | BCL2-associated X protein | 2.28967 |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type | 2.2595 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 2.24405 |
| HINFP | histone H4 transcription factor | 2.1829 |
| ATP10D | ATPase, class V, type 10D | 2.17305 |
| S100A1 | S100 calcium binding protein A1 | 2.15855 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa | 2.15365 |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 | 2.15243 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) | 2.14101 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 2.13163 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.13005 |
| SAV1 | salvador family WW domain containing protein 1 | 2.1168 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N | 2.0861 |
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 | 2.06075 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | 2.04815 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 2.0333 |
| C8G | complement component 8, gamma polypeptide | 2.02385 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 2.01055 |
| DBR1 | debranching RNA lariats 1 | 2.0089 |
| IRF3 | interferon regulatory factor 3 | 2.00655 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| GNAS | GNAS complex locus | -7.74421 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -6.4287 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -6.36385 |
| LAP3 | leucine aminopeptidase 3 | -5.25345 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -5.22315 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -5.11725 |
| CCNB1 | cyclin B1 | -4.93245 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.88645 |
| ADI1 | acireductone dioxygenase 1 | -4.8296 |
| CCNB2 | cyclin B2 | -4.7944 |
| FASTKD5 | FAST kinase domains 5 | -4.7027 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -3.4083 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -2.99825 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.9566 |
| ACLY | ATP citrate lyase | -2.90595 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.9048 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.8609 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.8235 |
| ADRM1 | adhesion regulating molecule 1 | -2.7787 |
| NDUFS4 | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | -2.75605 |
| COX6C | cytochrome c oxidase subunit VIc | -2.7546 |
| TMEM140 | transmembrane protein 140 | -2.7422 |
| SPON2 | spondin 2, extracellular matrix protein | -2.69375 |
| TUBA1C | tubulin, alpha 1c | -2.66805 |
| SNX11 | sorting nexin 11 | -2.58945 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -2.56515 |
| TUBA1B | tubulin, alpha 1b | -2.48975 |
| LAMP3 | lysosomal-associated membrane protein 3 | -2.39775 |
| DDX27 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | -2.38732 |
| SRFBP1 | serum response factor binding protein 1 | -2.35795 |
| RAD17 | RAD17 homolog (S. pombe) | -2.35398 |
| CCL22 | chemokine (C-C motif) ligand 22 | -2.34065 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | -2.33248 |
| LAMA5 | laminin, alpha 5 | -2.3204 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.31418 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | -2.29545 |
| KIF2A | kinesin heavy chain member 2A | -2.2789 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | -2.27005 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -2.26765 |
| ISCU | iron-sulfur cluster assembly enzyme | -2.2314 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 | -2.2267 |
| RPLP2 | ribosomal protein, large, P2 | -2.2192 |
| MCOLN3 | mucolipin 3 | -2.2079 |
| CS | citrate synthase | -2.20435 |
| BLCAP | bladder cancer associated protein | -2.1999 |
| RPS24 | ribosomal protein S24 | -2.18335 |
| CSNK1G3 | casein kinase 1, gamma 3 | -2.1764 |
| RGS19 | regulator of G-protein signaling 19 | -2.1687 |
| TUBA1A | tubulin, alpha 1a | -2.16101 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | -2.15205 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | -2.12395 |
| POMP | proteasome maturation protein | -2.1222 |
| CCNH | cyclin H | -2.1197 |
| IFI44 | interferon-induced protein 44 | -2.09115 |
| PPWD1 | peptidylprolyl isomerase domain and WD repeat containing 1 | -2.08325 |
| REPIN1 | replication initiator 1 | -2.07595 |
| CTSK | cathepsin K | -2.07495 |
| ASPN | asporin | -2.0743 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -2.07365 |
| SEM1 | SEM1 26S proteasome subunit | -2.05765 |
| MACF1 | microtubule-actin crosslinking factor 1 | -2.04804 |
| RPL36A | ribosomal protein L36a | -2.0406 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -2.03585 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B | -2.02662 |
| RPL11 | ribosomal protein L11 | -2.0231 |
| TGIF2 | TGFB-induced factor homeobox 2 | -2.02007 |
