| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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68 genes differentially expressed following the CRCGN008_HEPG2_24H:F09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 5.2665 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 5.2431 |
| CHMP6 | charged multivesicular body protein 6 | 5.21555 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 5.16015 |
| PLS1 | plastin 1 | 5.0 |
| ARL4C | ADP-ribosylation factor-like 4C | 4.82527 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.6999 |
| PRR15L | proline rich 15-like | 4.59305 |
| LOC122526780 | uncharacterized LOC122526780 | 4.2688 |
| GLOD4 | glyoxalase domain containing 4 | 4.2031 |
| CCDC85B | coiled-coil domain containing 85B | 3.4231 |
| CHN1 | chimerin 1 | 3.13535 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.93045 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 2.92775 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.81857 |
| HOOK2 | hook microtubule-tethering protein 2 | 2.74965 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 2.5405 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 2.47207 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.4065 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.401 |
| ZWILCH | zwilch kinetochore protein | 2.36695 |
| NMU | neuromedin U | 2.313 |
| WASF3 | WAS protein family, member 3 | 2.21695 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.17135 |
| EVL | Enah/Vasp-like | 2.1024 |
| PARP1 | poly (ADP-ribose) polymerase 1 | 2.0507 |
| UNG | uracil-DNA glycosylase | 2.04985 |
| RHOA | ras homolog family member A | 2.01837 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.01365 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 2.01025 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.00965 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -10.0 |
| ZNF586 | zinc finger protein 586 | -5.77575 |
| COG7 | component of oligomeric golgi complex 7 | -5.2901 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.9963 |
| FASTKD5 | FAST kinase domains 5 | -4.8503 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -4.84065 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.8148 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -4.7903 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.57815 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.23095 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -3.86643 |
| LRRC41 | leucine rich repeat containing 41 | -3.31198 |
| ANKRD10 | ankyrin repeat domain 10 | -3.1615 |
| CAB39 | calcium binding protein 39 | -3.0187 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.8957 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.87535 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.7674 |
| TBX2 | T-box 2 | -2.64008 |
| HSPA8 | heat shock 70kDa protein 8 | -2.58913 |
| ZFPM1 | zinc finger protein, FOG family member 1 | -2.3875 |
| ICAM3 | intercellular adhesion molecule 3 | -2.3417 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.30595 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | -2.2643 |
| HOXD10 | homeobox D10 | -2.26365 |
| PYGO1 | pygopus family PHD finger 1 | -2.1819 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -2.1711 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -2.13785 |
| NCK2 | NCK adaptor protein 2 | -2.135 |
| PCDHGA8 | protocadherin gamma subfamily A, 8 | -2.122 |
| HOXD9 | homeobox D9 | -2.11995 |
| ZNF614 | zinc finger protein 614 | -2.10952 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | -2.0904 |
| CALCA | calcitonin-related polypeptide alpha | -2.08264 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | -2.08255 |
| ZNF276 | zinc finger protein 276 | -2.07685 |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide | -2.06897 |
| CYP2F1 | cytochrome P450, family 2, subfamily F, polypeptide 1 | -2.05075 |
