| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dehydroisoandosterone 20.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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86 genes differentially expressed following the CRCGN008_HEPG2_24H:F14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.61835 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.3033 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 5.13965 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.09945 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.038 |
| ADRB2 | adrenoceptor beta 2, surface | 5.0 |
| MYLK | myosin light chain kinase | 4.7658 |
| SH3D19 | SH3 domain containing 19 | 3.92505 |
| PRR15L | proline rich 15-like | 3.45135 |
| CDC45 | cell division cycle 45 | 3.31305 |
| ALDOC | aldolase C, fructose-bisphosphate | 3.28805 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 3.22368 |
| CCNF | cyclin F | 2.93447 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 2.83435 |
| SFTPB | surfactant protein B | 2.82087 |
| ORM1 | orosomucoid 1 | 2.8033 |
| GRWD1 | glutamate-rich WD repeat containing 1 | 2.80155 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | 2.69563 |
| APOB | apolipoprotein B | 2.6708 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.63322 |
| ORM2 | orosomucoid 2 | 2.51725 |
| CYCS | cytochrome c, somatic | 2.5086 |
| AXIN1 | axin 1 | 2.4736 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.39648 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.33783 |
| AMBP | alpha-1-microglobulin/bikunin precursor | 2.3182 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 | 2.2704 |
| APOC3 | apolipoprotein C-III | 2.24695 |
| CES1 | carboxylesterase 1 | 2.23665 |
| CEP57 | centrosomal protein 57kDa | 2.22219 |
| KLHL9 | kelch-like family member 9 | 2.19547 |
| SKIC2 | SKI2 subunit of superkiller complex | 2.1673 |
| TNIP1 | TNFAIP3 interacting protein 1 | 2.1567 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 2.11125 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.09405 |
| HOMER2 | homer scaffolding protein 2 | 2.08393 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) | 2.0802 |
| CAPN2 | calpain 2, (m/II) large subunit | 2.0581 |
| GSTT1 | glutathione S-transferase theta 1 | 2.03615 |
| MYOM1 | myomesin 1 | 2.0122 |
| NRSN2 | neurensin 2 | 2.00145 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 | 2.001 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -5.41125 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.2455 |
| CD320 | CD320 molecule | -5.1933 |
| CCNB2 | cyclin B2 | -4.9619 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.85225 |
| TLCD3A | TLC domain containing 3A | -4.8471 |
| ELAC2 | elaC ribonuclease Z 2 | -4.8328 |
| MAP7 | microtubule-associated protein 7 | -4.82217 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -4.78185 |
| MRPS16 | mitochondrial ribosomal protein S16 | -4.5962 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -4.2407 |
| NGRN | neugrin, neurite outgrowth associated | -4.19305 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.84318 |
| PRPF4 | pre-mRNA processing factor 4 | -3.74402 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -3.29378 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.2218 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -2.9128 |
| SNX11 | sorting nexin 11 | -2.88707 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.7305 |
| EIF2B2 | eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa | -2.7138 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.6545 |
| CLIC4 | chloride intracellular channel 4 | -2.64642 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.54605 |
| CCP110 | centriolar coiled coil protein 110kDa | -2.52275 |
| MRPL58 | mitochondrial ribosomal protein L58 | -2.444 |
| TXNDC9 | thioredoxin domain containing 9 | -2.36417 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -2.33705 |
| ACOT13 | acyl-CoA thioesterase 13 | -2.25375 |
| CTC1 | CTS telomere maintenance complex component 1 | -2.25 |
| ZNF536 | zinc finger protein 536 | -2.2105 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | -2.20515 |
| HSPA8 | heat shock 70kDa protein 8 | -2.1869 |
| GRM3 | glutamate receptor, metabotropic 3 | -2.1661 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 | -2.14855 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.1429 |
| VPS26A | vacuolar protein sorting 26 homolog A (S. pombe) | -2.09905 |
| POMT1 | protein-O-mannosyltransferase 1 | -2.0938 |
| TPK1 | thiamin pyrophosphokinase 1 | -2.0929 |
| GLOD4 | glyoxalase domain containing 4 | -2.0628 |
| LRP2 | low density lipoprotein receptor-related protein 2 | -2.05535 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -2.0332 |
| ASPA | aspartoacylase | -2.0084 |
| TUBB6 | tubulin, beta 6 class V | -2.0009 |
