| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dehydroisoandosterone 5.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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59 genes differentially expressed following the CRCGN008_HEPG2_24H:F16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 5.98542 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.9091 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 5.344 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 5.16515 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 4.69945 |
| PRR15L | proline rich 15-like | 4.26185 |
| EGF | epidermal growth factor | 4.16625 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.1228 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.93255 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.47395 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 3.47077 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.24525 |
| MMP1 | matrix metallopeptidase 1 | 3.21498 |
| ZNF589 | zinc finger protein 589 | 3.13648 |
| WDR7 | WD repeat domain 7 | 3.0376 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.64908 |
| TRIM13 | tripartite motif containing 13 | 2.54505 |
| EPHA3 | EPH receptor A3 | 2.48533 |
| NEUROD6 | neuronal differentiation 6 | 2.40385 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 2.3441 |
| ZNF514 | zinc finger protein 514 | 2.32025 |
| POLR2K | polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa | 2.28898 |
| CHN1 | chimerin 1 | 2.21155 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.15765 |
| NHLRC2 | NHL repeat containing 2 | 2.153 |
| CLEC1A | C-type lectin domain family 1, member A | 2.09445 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.07365 |
| NOSIP | nitric oxide synthase interacting protein | 2.03615 |
| GSTCD | glutathione S-transferase, C-terminal domain containing | 2.02115 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC35F2 | solute carrier family 35, member F2 | -5.2589 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -5.2072 |
| ZNF586 | zinc finger protein 586 | -5.1664 |
| CD320 | CD320 molecule | -4.9121 |
| CCNB2 | cyclin B2 | -4.89435 |
| LDHD | lactate dehydrogenase D | -4.60725 |
| CAB39 | calcium binding protein 39 | -4.3093 |
| CLTB | clathrin, light chain B | -3.42879 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -3.09868 |
| DMAC2L | distal membrane arm assembly component 2 like | -3.02377 |
| CCP110 | centriolar coiled coil protein 110kDa | -2.9638 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.89035 |
| KLK5 | kallikrein-related peptidase 5 | -2.8081 |
| CCNB1 | cyclin B1 | -2.4294 |
| ZNF134 | zinc finger protein 134 | -2.4183 |
| SELENOF | selenoprotein F | -2.358 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -2.3034 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.19732 |
| KLK8 | kallikrein-related peptidase 8 | -2.1757 |
| WASHC4 | WASH complex subunit 4 | -2.1565 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | -2.14605 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | -2.0838 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 | -2.07715 |
| CACNA1B | calcium channel, voltage-dependent, N type, alpha 1B subunit | -2.0708 |
| VRTN | vertebrae development associated | -2.0559 |
| CHRNE | cholinergic receptor, nicotinic, epsilon (muscle) | -2.05315 |
| GNL2 | guanine nucleotide binding protein-like 2 (nucleolar) | -2.05215 |
| ZNF671 | zinc finger protein 671 | -2.0292 |
| GAB2 | GRB2-associated binding protein 2 | -2.01635 |
| UIMC1 | ubiquitin interaction motif containing 1 | -2.0128 |
