| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | triprolidine.hcl monohydrate 38.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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54 genes differentially expressed following the CRCGN008_HEPG2_24H:F19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 9.9874 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 5.20045 |
| ADRB2 | adrenoceptor beta 2, surface | 4.82195 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.6755 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 4.32495 |
| RPL39L | ribosomal protein L39-like | 4.1675 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 3.99095 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.4741 |
| TBPL1 | TBP-like 1 | 3.2694 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.9458 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 2.7182 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.67115 |
| USP6NL | USP6 N-terminal like | 2.6173 |
| KIF20A | kinesin family member 20A | 2.6035 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 2.54363 |
| CORO1A | coronin, actin binding protein, 1A | 2.45415 |
| CHN1 | chimerin 1 | 2.40595 |
| FOXJ3 | forkhead box J3 | 2.2715 |
| EPHA3 | EPH receptor A3 | 2.2356 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 2.12385 |
| CCT3 | chaperonin containing TCP1, subunit 3 (gamma) | 2.11555 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 2.11025 |
| TTC27 | tetratricopeptide repeat domain 27 | 2.0673 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | 2.0588 |
| VWF | von Willebrand factor | 2.04235 |
| SMG9 | SMG9 nonsense mediated mRNA decay factor | 2.0258 |
| FABP4 | fatty acid binding protein 4, adipocyte | 2.0117 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -5.18395 |
| CD320 | CD320 molecule | -4.9121 |
| CDC20 | cell division cycle 20 | -4.6933 |
| FASTKD5 | FAST kinase domains 5 | -4.1065 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.8517 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.7851 |
| PRPF4 | pre-mRNA processing factor 4 | -3.7407 |
| GNAS | GNAS complex locus | -3.49093 |
| CCNB2 | cyclin B2 | -3.4627 |
| PGM1 | phosphoglucomutase 1 | -3.31315 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.08615 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -2.97875 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.80545 |
| MALT1 | MALT1 paracaspase | -2.65243 |
| HSPA8 | heat shock 70kDa protein 8 | -2.55143 |
| CHPF2 | chondroitin polymerizing factor 2 | -2.3249 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -2.18355 |
| RNF167 | ring finger protein 167 | -2.15615 |
| S100A4 | S100 calcium binding protein A4 | -2.1336 |
| S1PR4 | sphingosine-1-phosphate receptor 4 | -2.10485 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -2.0842 |
| THAP4 | THAP domain containing 4 | -2.08325 |
| GPR15 | G protein-coupled receptor 15 | -2.07155 |
| AMN | amnion associated transmembrane protein | -2.0642 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | -2.0582 |
| BORCS6 | BLOC-1 related complex subunit 6 | -2.02415 |
| MFAP4 | microfibrillar-associated protein 4 | -2.00975 |
