| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | triprolidine.hcl monohydrate 9.5 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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59 genes differentially expressed following the CRCGN008_HEPG2_24H:F21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.88785 |
| ATP11B | ATPase, class VI, type 11B | 5.6252 |
| ADRB2 | adrenoceptor beta 2, surface | 5.38255 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 5.2758 |
| UBQLN2 | ubiquilin 2 | 4.82625 |
| CBR3 | carbonyl reductase 3 | 4.5826 |
| FZD7 | frizzled class receptor 7 | 4.39528 |
| SSBP2 | single-stranded DNA binding protein 2 | 4.00822 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 3.67368 |
| CDCA4 | cell division cycle associated 4 | 3.59515 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 3.59275 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 3.56157 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.43822 |
| CYCS | cytochrome c, somatic | 3.2741 |
| CCNF | cyclin F | 3.08107 |
| PLSCR3 | phospholipid scramblase 3 | 2.8931 |
| TBPL1 | TBP-like 1 | 2.81765 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.753 |
| PMM2 | phosphomannomutase 2 | 2.60295 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.59807 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.568 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.49125 |
| VEGFD | vascular endothelial growth factor D | 2.4671 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 2.43305 |
| CHEK2 | checkpoint kinase 2 | 2.34107 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 2.26905 |
| SCRN1 | secernin 1 | 2.2468 |
| MORF4L2 | mortality factor 4 like 2 | 2.21315 |
| APOB | apolipoprotein B | 2.14675 |
| KLHL9 | kelch-like family member 9 | 2.14438 |
| PHOSPHO2-KLHL23 | PHOSPHO2-KLHL23 readthrough | 2.04205 |
| KAT6A | K(lysine) acetyltransferase 6A | 2.00978 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| TLCD3A | TLC domain containing 3A | -5.5428 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -5.22315 |
| ADI1 | acireductone dioxygenase 1 | -5.2073 |
| CCNB2 | cyclin B2 | -4.8638 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -4.75882 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.7331 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.38165 |
| FASTKD5 | FAST kinase domains 5 | -4.1775 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.6494 |
| ICAM3 | intercellular adhesion molecule 3 | -3.6042 |
| WASHC4 | WASH complex subunit 4 | -3.49297 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -3.2823 |
| TWF2 | twinfilin actin binding protein 2 | -2.84895 |
| HMG20B | high mobility group 20B | -2.6273 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.57925 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -2.4695 |
| THEMIS2 | thymocyte selection associated family member 2 | -2.3553 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.34302 |
| SCAND1 | SCAN domain containing 1 | -2.3185 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.30475 |
| UNC119 | unc-119 homolog (C. elegans) | -2.2187 |
| ARHGAP4 | Rho GTPase activating protein 4 | -2.16495 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -2.13945 |
| ASL | argininosuccinate lyase | -2.0895 |
| CD58 | CD58 molecule | -2.03535 |
| RESF1 | retroelement silencing factor 1 | -2.02365 |
