| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | triprolidine.hcl monohydrate 4.75 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
87 genes differentially expressed following the CRCGN008_HEPG2_24H:F22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 5.18445 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 5.15065 |
| ARL4C | ADP-ribosylation factor-like 4C | 5.08737 |
| TRIM13 | tripartite motif containing 13 | 4.82535 |
| PLS1 | plastin 1 | 4.7807 |
| STIMATE | STIM activating enhancer | 4.65495 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 4.05275 |
| LOC122526780 | uncharacterized LOC122526780 | 3.8767 |
| PRR15L | proline rich 15-like | 3.8243 |
| GPATCH8 | G patch domain containing 8 | 3.38182 |
| RXYLT1 | ribitol xylosyltransferase 1 | 3.33103 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 3.16127 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.9363 |
| SLC75A1 | solute carrier family 75 member 1 | 2.91465 |
| KIF20A | kinesin family member 20A | 2.67225 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.62072 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.5214 |
| IL10RB | interleukin 10 receptor, beta | 2.4575 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 2.4329 |
| SIRT3 | sirtuin 3 | 2.41838 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.4021 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.3617 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 2.3607 |
| FBXO17 | F-box protein 17 | 2.34705 |
| PHACTR4 | phosphatase and actin regulator 4 | 2.32845 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 | 2.2709 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 2.2618 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 2.1614 |
| RPGR | retinitis pigmentosa GTPase regulator | 2.1595 |
| KIF18A | kinesin family member 18A | 2.15615 |
| MEGF8 | multiple EGF-like-domains 8 | 2.1537 |
| DNAH7 | dynein, axonemal, heavy chain 7 | 2.14375 |
| ZNF324B | zinc finger protein 324B | 2.1153 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.0853 |
| MARCHF2 | membrane associated ring-CH-type finger 2 | 2.0754 |
| HEBP1 | heme binding protein 1 | 2.06725 |
| DCAF10 | DDB1 and CUL4 associated factor 10 | 2.06375 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.06021 |
| CFHR2 | complement factor H-related 2 | 2.05205 |
| ILF2 | interleukin enhancer binding factor 2 | 2.0314 |
| C8G | complement component 8, gamma polypeptide | 2.02815 |
| RAB5C | RAB5C, member RAS oncogene family | 2.02513 |
| TDRD7 | tudor domain containing 7 | 2.01865 |
| CAPRIN1 | cell cycle associated protein 1 | 2.00478 |
| IFT88 | intraflagellar transport 88 | 2.0046 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -5.58895 |
| SLC35F2 | solute carrier family 35, member F2 | -5.5849 |
| NGRN | neugrin, neurite outgrowth associated | -5.57285 |
| TLCD3A | TLC domain containing 3A | -5.5428 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -5.2125 |
| ADI1 | acireductone dioxygenase 1 | -5.09995 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -5.0 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -4.56105 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -4.20395 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.8551 |
| GNAS | GNAS complex locus | -3.7565 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -3.59445 |
| PEG10 | paternally expressed 10 | -3.55237 |
| SCAND1 | SCAN domain containing 1 | -3.3776 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) | -2.9699 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.93085 |
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 | -2.89635 |
| MRPS33 | mitochondrial ribosomal protein S33 | -2.74605 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.61188 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.5187 |
| LOC107986346 | mitochondrial import receptor subunit TOM7 homolog | -2.49735 |
| PIGK | phosphatidylinositol glycan anchor biosynthesis, class K | -2.4651 |
| NDUFB3 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa | -2.3614 |
| NDUFA3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa | -2.3581 |
| SCAF8 | SR-related CTD-associated factor 8 | -2.34405 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.29782 |
| H2AJ | H2A.J histone | -2.2859 |
| MRPL46 | mitochondrial ribosomal protein L46 | -2.27365 |
| TXNDC9 | thioredoxin domain containing 9 | -2.23595 |
| ISCU | iron-sulfur cluster assembly enzyme | -2.19875 |
| DENR | density-regulated protein | -2.19335 |
| CLCC1 | chloride channel CLIC-like 1 | -2.149 |
| NOP14 | NOP14 nucleolar protein | -2.13535 |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa | -2.12755 |
| COX7C | cytochrome c oxidase subunit VIIc | -2.11958 |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P | -2.0739 |
| CCL21 | chemokine (C-C motif) ligand 21 | -2.0447 |
| ACYP2 | acylphosphatase 2, muscle type | -2.03495 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -2.03195 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | -2.01513 |
| KRABD4 | KRAB domain containing 4 | -2.00445 |
