| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | triprolidine.hcl monohydrate 2.37 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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58 genes differentially expressed following the CRCGN008_HEPG2_24H:F23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.5254 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.96495 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 4.7963 |
| CCNA1 | cyclin A1 | 4.7335 |
| CHMP6 | charged multivesicular body protein 6 | 4.44425 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.2377 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 3.9227 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 3.52812 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.38462 |
| PRR15L | proline rich 15-like | 3.37095 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 3.28715 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 3.22445 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.10592 |
| RPA3 | replication protein A3, 14kDa | 2.9073 |
| KLHL9 | kelch-like family member 9 | 2.78518 |
| MCM3 | minichromosome maintenance complex component 3 | 2.7593 |
| TBP | TATA box binding protein | 2.67445 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | 2.669 |
| KIF20A | kinesin family member 20A | 2.5483 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.53175 |
| GPATCH8 | G patch domain containing 8 | 2.46598 |
| SMAD3 | SMAD family member 3 | 2.45255 |
| HSPB1 | heat shock 27kDa protein 1 | 2.43805 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 2.37995 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 | 2.26785 |
| ECD | ecdysoneless homolog (Drosophila) | 2.13105 |
| EPHA3 | EPH receptor A3 | 2.12383 |
| KRT19 | keratin 19, type I | 2.1219 |
| AXIN1 | axin 1 | 2.091 |
| EVL | Enah/Vasp-like | 2.08715 |
| RPP30 | ribonuclease P/MRP 30kDa subunit | 2.02925 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -5.24085 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -5.18315 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -5.1296 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.09935 |
| CD320 | CD320 molecule | -4.85565 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.78395 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -4.21505 |
| FASTKD5 | FAST kinase domains 5 | -4.0372 |
| CCNB2 | cyclin B2 | -3.909 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -3.74775 |
| RAI14 | retinoic acid induced 14 | -3.68965 |
| CCNB1 | cyclin B1 | -3.6178 |
| PRPF4 | pre-mRNA processing factor 4 | -3.22918 |
| CDC25B | cell division cycle 25B | -3.0629 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.99625 |
| RBM6 | RNA binding motif protein 6 | -2.97365 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.8989 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.89 |
| ATF5 | activating transcription factor 5 | -2.83305 |
| NISCH | nischarin | -2.6754 |
| RNF167 | ring finger protein 167 | -2.59465 |
| WASHC4 | WASH complex subunit 4 | -2.45102 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -2.2154 |
| LORICRIN | loricrin cornified envelope precursor protein | -2.1163 |
| CPAMD8 | C3 and PZP-like, alpha-2-macroglobulin domain containing 8 | -2.10295 |
| SERPINB7 | serpin peptidase inhibitor, clade B (ovalbumin), member 7 | -2.09855 |
| MACIR | macrophage immunometabolism regulator | -2.03395 |
