CRCGN008_HEPG2_24H:G09 Gene Set
Genes
54 genes differentially expressed following the CRCGN008_HEPG2_24H:G09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CYCS
|
cytochrome c, somatic
|
6.2957
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
5.79835
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
5.71105
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
5.45585
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
5.38945
|
|
RPL39L
|
ribosomal protein L39-like
|
5.25565
|
|
NMU
|
neuromedin U
|
4.82815
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
4.82595
|
|
STAP2
|
signal transducing adaptor family member 2
|
4.66275
|
|
CEP57
|
centrosomal protein 57kDa
|
3.59858
|
|
BAMBI
|
BMP and activin membrane-bound inhibitor
|
2.9345
|
|
FPGS
|
folylpolyglutamate synthase
|
2.7423
|
|
OAS2
|
2'-5'-oligoadenylate synthetase 2, 69/71kDa
|
2.49825
|
|
ZNF589
|
zinc finger protein 589
|
2.4519
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.36433
|
|
PMM2
|
phosphomannomutase 2
|
2.33865
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.287
|
|
MX2
|
MX dynamin-like GTPase 2
|
2.2185
|
|
CDCA4
|
cell division cycle associated 4
|
2.1809
|
|
CCR5
|
chemokine (C-C motif) receptor 5 (gene/pseudogene)
|
2.13125
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
2.10095
|
|
CDK19
|
cyclin-dependent kinase 19
|
2.07707
|
|
MX1
|
MX dynamin-like GTPase 1
|
2.02545
|
|
DDX60
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
|
2.0053
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-5.1402
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.86025
|
|
MAP7
|
microtubule-associated protein 7
|
-4.45095
|
|
FASTKD5
|
FAST kinase domains 5
|
-4.40885
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.2582
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.70173
|
|
CLIC4
|
chloride intracellular channel 4
|
-3.317
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-3.27205
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-3.19673
|
|
WASHC4
|
WASH complex subunit 4
|
-3.00802
|
|
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1
|
-2.9262
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
-2.7486
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.72943
|
|
PLA2G15
|
phospholipase A2, group XV
|
-2.68645
|
|
SNX11
|
sorting nexin 11
|
-2.67313
|
|
NISCH
|
nischarin
|
-2.6115
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.49942
|
|
CEL
|
carboxyl ester lipase
|
-2.434
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.34575
|
|
RHOF
|
ras homolog family member F (in filopodia)
|
-2.28455
|
|
C1GALT1C1
|
C1GALT1-specific chaperone 1
|
-2.2253
|
|
ARID4A
|
AT rich interactive domain 4A (RBP1-like)
|
-2.2124
|
|
RPA4
|
replication protein A4, 30kDa
|
-2.19405
|
|
KIAA0319
|
KIAA0319
|
-2.16055
|
|
SLC16A7
|
solute carrier family 16 (monocarboxylate transporter), member 7
|
-2.15815
|
|
LRPAP1
|
low density lipoprotein receptor-related protein associated protein 1
|
-2.1146
|
|
CBX6
|
chromobox homolog 6
|
-2.1059
|
|
SNPH
|
syntaphilin
|
-2.04625
|
|
SBNO1
|
strawberry notch homolog 1 (Drosophila)
|
-2.0065
|
