| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | methoxychlor 5.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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90 genes differentially expressed following the CRCGN008_HEPG2_24H:G10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.49985 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 5.45955 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 5.30495 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.03565 |
| PRR15L | proline rich 15-like | 4.91285 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 4.4056 |
| CYCS | cytochrome c, somatic | 3.5666 |
| GATA2 | GATA binding protein 2 | 3.2601 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | 3.19955 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 3.08795 |
| NENF | neudesin neurotrophic factor | 3.05352 |
| METRN | meteorin, glial cell differentiation regulator | 3.0419 |
| CORO1A | coronin, actin binding protein, 1A | 3.03905 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.9198 |
| CCDC85B | coiled-coil domain containing 85B | 2.78275 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.7824 |
| TNIP1 | TNFAIP3 interacting protein 1 | 2.7676 |
| ZNF589 | zinc finger protein 589 | 2.75852 |
| GPATCH8 | G patch domain containing 8 | 2.60467 |
| KIF20A | kinesin family member 20A | 2.601 |
| HBE1 | hemoglobin, epsilon 1 | 2.4155 |
| HMOX1 | heme oxygenase 1 | 2.41475 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | 2.38655 |
| CCNF | cyclin F | 2.36972 |
| AXIN1 | axin 1 | 2.3297 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 2.3124 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.27232 |
| APOO | apolipoprotein O | 2.2285 |
| CDC45 | cell division cycle 45 | 2.2049 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | 2.15975 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 2.1573 |
| HSPB1 | heat shock 27kDa protein 1 | 2.1396 |
| HBZ | hemoglobin, zeta | 2.1242 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | 2.119 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 2.09865 |
| FXYD6-FXYD2 | FXYD6-FXYD2 readthrough | 2.0931 |
| DPH2 | DPH2 homolog (S. cerevisiae) | 2.08385 |
| BCL7C | B-cell CLL/lymphoma 7C | 2.0682 |
| FAM149A | family with sequence similarity 149, member A | 2.05868 |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | 2.05485 |
| DCTD | dCMP deaminase | 2.04408 |
| ABHD14A | abhydrolase domain containing 14A | 2.03705 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | 2.02155 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 2.01087 |
| HSD17B10 | hydroxysteroid (17-beta) dehydrogenase 10 | 2.00315 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -10.0 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -6.86535 |
| GOLT1B | golgi transport 1B | -5.6443 |
| PCNA | proliferating cell nuclear antigen | -5.193 |
| CCNB2 | cyclin B2 | -4.6401 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | -4.426 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -4.17405 |
| FASTKD5 | FAST kinase domains 5 | -4.10575 |
| MAPK13 | mitogen-activated protein kinase 13 | -4.07018 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.9695 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.80955 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.72757 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase | -3.41035 |
| RBM15B | RNA binding motif protein 15B | -3.34195 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -3.25615 |
| ANKRD10 | ankyrin repeat domain 10 | -3.1509 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -3.01168 |
| CDC25B | cell division cycle 25B | -2.91635 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.72802 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.6876 |
| RECQL | RecQ helicase-like | -2.66674 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -2.5225 |
| MFSD6 | major facilitator superfamily domain containing 6 | -2.5066 |
| HOXD1 | homeobox D1 | -2.4844 |
| EPHA4 | EPH receptor A4 | -2.4807 |
| PANX1 | pannexin 1 | -2.45215 |
| WASF1 | WAS protein family, member 1 | -2.3446 |
| CCNH | cyclin H | -2.3252 |
| EXT1 | exostosin glycosyltransferase 1 | -2.31185 |
| NISCH | nischarin | -2.30335 |
| FRK | fyn-related Src family tyrosine kinase | -2.2408 |
| CHEK1 | checkpoint kinase 1 | -2.20907 |
| PARG | poly (ADP-ribose) glycohydrolase | -2.20245 |
| STAG3 | stromal antigen 3 | -2.18825 |
| ACVR1 | activin A receptor, type I | -2.16165 |
| PRPF4 | pre-mRNA processing factor 4 | -2.1569 |
| CDK6 | cyclin-dependent kinase 6 | -2.12565 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | -2.12145 |
| MOBP | myelin-associated oligodendrocyte basic protein | -2.1173 |
| PROS1 | protein S (alpha) | -2.10215 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | -2.08365 |
| PRR5L | proline rich 5 like | -2.054 |
| RFX7 | regulatory factor X, 7 | -2.0384 |
| ZNF155 | zinc finger protein 155 | -2.02165 |
| GUCY1B1 | guanylate cyclase 1 soluble subunit beta 1 | -2.00785 |
